Guideline for the clinical application of transcranial alternating current stimulation [0.03%]
经颅交流电刺激临床应用指南
Penghui Song,Xiaotong Yang,Nuo Yang et al.
Penghui Song et al.
Hydrogen sulfide attenuates oxidative stress-induced cellular senescence via the Sirt3/SOD2 signaling pathway in chronic obstructive pulmonary disease [0.03%]
慢性阻塞性肺疾病中氢硫化物通过Sirt3/SOD2信号通路减轻氧化应激诱导的细胞衰老
Sha Liao,Dian Chen,Huanyu Long et al.
Sha Liao et al.
Background: Senescence significantly participates in shaping the pathobiological process underlying chronic obstructive pulmonary disease (COPD). Currently, the mechanisms underlying the anti-aging effects within COPD of ...
Small nucleolar RNA host gene 1 (SNHG1) facilitates gemcitabine chemosensitivity in gallbladder cancer by regulating the miR-23b-3p/phosphatase and tensin homolog (PTEN) pathway [0.03%]
小核仁RNA宿主基因1（SNHG1）通过调节miR-23b-3p/磷酸酶和张力同源物（PTEN）通路促进胆囊癌对吉西他滨的化疗敏感性
Hui Wang,Yixiang Gu,Miaomiao Guo et al.
Hui Wang et al.
Background: Growing evidence suggests that long non-coding RNAs (lncRNAs) exert pivotal roles in fostering chemoresistance across diverse tumors. Nevertheless, the precise involvement of lncRNAs in modulating chemoresista...
Xibei Chen,Yuxin Zheng,Xiaoyong Man et al.
Xibei Chen et al.
Tissue-resident memory T (TRM) cells are a recently defined subtype of non-recirculating memory T cells with longevity and protective functions in peripheral tissues. As an essential frontline defense against infections, TRM cells have been...
Tissue-resident peripheral helper T cells foster hepatocellular carcinoma immune evasion by promoting regulatory B-cell expansion [0.03%]
组织驻留外周辅助T细胞通过促进调节性B细胞的扩增帮助肝细胞癌免疫逃逸
Haoyuan Yu,Mengchen Shi,Xuejiao Li et al.
Haoyuan Yu et al.
Background: peripheral helper T (TPH) cells are uniquely positioned within pathologically inflamed non-lymphoid tissues to stimulate B-cell responses and antibody production. However, the phenotype, function, and clinical...
Modeling epilepsy by loss-of-function of the CUG-binding protein Elav-like family member 2 in zebrafish with multi-omics analysis [0.03%]
斑马鱼CUG结合蛋白Elav样家族成员2功能丧失引起的多组分分析下的癫痫研究模型
Xiaoqian Wang,Jia Zhang,Xueyi Rao et al.
Xiaoqian Wang et al.
Background: The CUG-binding protein Elav-like family member 2 (CELF2) gene has been linked to the pathogenesis of epilepsy, but its precise role remains unclear. This study aimed to investigate the pathogenic mechanisms o...
Increasing trends of hyperglycemia and diabetes in treatment-naive people living with HIV in Shenzhen from 2013 to 2019: An emerging health concern [0.03%]
2013至2019年期间深圳未接受过治疗的HIV感染者的高血糖和糖尿病增多趋势：一个新兴的健康问题
Liqin Sun,Haipeng Zhu,Man Rao et al.
Liqin Sun et al.
Safety and efficacy of human umbilical cord-derived mesenchymal stem cells in COVID-19 patients: A real-world observation [0.03%]
人脐带来源的间充质干细胞在COVID-19患者中的安全性和有效性：现实世界观察
Siyu Wang,Tao Yang,Tiantian Li et al.
Siyu Wang et al.
Background: The effects of human umbilical cord-derived mesenchymal stem cell (UC-MSC) treatment on coronavirus disease 2019 (COVID-19) patients have been preliminarily characterized. However, real-world data on the safet...
Complex associations among modifiable determinants of circadian syndrome among employed people in southwestern China [0.03%]
中国西南部在职人群昼夜节律综合征相关因素的复杂关联分析
Shujuan Yang,Peng Jia,Lei Zhang et al.
Shujuan Yang et al.
Background: Circadian syndrome (CircS) may be closely linked to lifestyle, psychological, and occupational factors, but evidence is lacking. This study aimed to explore complex associations between lifestyle, psychologica...
LncRNA H19 overexpression protects against acute kidney injury after cardiopulmonary bypass via activating Pink1/Parkin-mediated mitophagy [0.03%]
长链非编码RNA H19过表达通过激活Pink1/Parkin介导的线粒体自噬保护心脏肺旁路术后急性肾损伤
Mingru Zhang,Min Liu,Tianlong Wang et al.
Mingru Zhang et al.
Background: Cardiopulmonary bypass-associated acute kidney injury (CPB-AKI) is a serious and common complication following cardiopulmonary bypass (CPB), leading to worse outcomes and higher mortality. However, the underly...