Computational pathology in precision oncology: Evolution from task-specific models to foundation models [0.03%]
计算病理学在精准肿瘤学中的应用：从任务特定模型到基础模型的演变
Yuhao Wang,Yunjie Gu,Xueyuan Zhang et al.
Yuhao Wang et al.
With the rapid development of artificial intelligence, computational pathology has been seamlessly integrated into the entire clinical workflow, which encompasses diagnosis, treatment, prognosis, and biomarker discovery. This integration ha...
Adherence to blood glucose self-monitoring guidance and glycemic control in Chinese patients with type 2 diabetes mellitus initiating basal insulin: A mobile health-based prospective cohort study [0.03%]
中国2型糖尿病患者起始基础胰岛素治疗时的自我血糖监测依从性及其与血糖控制之间的关系：基于移动医疗技术的前瞻性队列研究
Lixin Guo,Dalong Zhu,Kaining Chen et al.
Lixin Guo et al.
Associations between statins and all-cause mortality and cardiovascular events among peritoneal dialysis patients: A multi-center large-scale cohort study [0.03%]
他汀类药物与腹膜透析患者全因死亡及心血管事件的关联：一项多中心大规模队列研究
Shuang Gao,Lei Nan,Xinqiu Li et al.
Shuang Gao et al.
Key role of KRT6A in interstitial cystitis: Machine learning-identified feature genes for bladder pain, immunity and fibrosis [0.03%]
KRT6A在间质性膀胱炎中的关键作用：与膀胱痛、免疫和纤维化相关的机器学习鉴定特征基因
Li Tao,Xuejian Zhou,Ying Xiao et al.
Li Tao et al.
Multimodal profiling identifies CD4+CXCR5+PD-1- Tfh cells as prognostic and predictive biomarkers in diffuse large B-cell lymphoma [0.03%]
多模态谱型分析确定CD4+CXCR5+PD-1- Tfh细胞作为弥漫性大B细胞淋巴瘤的预后及预测生物标志物
Sisi Yu,Hao Kong,Huaichao Luo et al.
Sisi Yu et al.
Summary of the 2024 report on gastroenterology and digestive endoscopy in China [0.03%]
中国2024年胃肠病学与消化内镜报告摘要
Zheran Chen,Yusi Xu,Lei Xin et al.
Zheran Chen et al.
Background: China has made significant progress in medical accessibility and quality over the past decades, and quality improvements in gastroenterology and digestive endoscopy have been consistent. The study aimed to des...
Long-term outcomes of CNCT19 chimeric antigen receptor T-cell therapy in relapsed or refractory aggressive B-cell lymphoma [0.03%]
抗CD19嵌合抗原受体T细胞治疗复发或难治侵袭性B细胞淋巴瘤的长期疗效
Wei Liu,Ting Xie,Zhuoxin Zhang et al.
Wei Liu et al.
Background: Most anti-CD19 chimeric antigen receptor (CAR) T-cell products have the single-chain variable fragment (scFv) derived from the FMC63 monoclonal antibody. We developed a new hybridoma clone, HI19α, which binds...
Exercise-induced angiogenesis and lymphangiogenesis: A potential therapeutic tool to fight aging and disease [0.03%]
运动诱导的血管生成和淋巴管生成：对抗衰老和疾病的潜在治疗工具
Jizong Jiang,Yongjun Zheng,Rui Wang et al.
Jizong Jiang et al.
Aging is an inevitable, physiological process of the human body, leading to deterioration in bodily function and increased susceptibility to various diseases. Effective endogenous therapeutic strategies for anti-aging and related diseases r...
Kaempferide inhibited progression of osteoarthritis by targeting the HIF-1 signaling pathway [0.03%]
千斤拔内酯通过靶向缺氧诱导因子-1信号通路抑制骨关节炎进展
Xianjie Wei,Hesuyuan Huang,Ping Yuan et al.
Xianjie Wei et al.
Background: Osteoarthritis (OA) is a prevalent joint disorder that significantly impairs quality of life among elderly individuals because of chronic pain and physical disability. As the global burden of OA continues to r...
m6A-modified circCD2AP suppressed ferroptosis in bladder cancer by upregulating FOXC1 to promote PARK7 transcriptional activity [0.03%]
通过上调FOXC1促进PARK7转录活性以抑制铁死亡circCD2AP在膀胱癌中的m6A修饰作用
Jinrong Wang,Jianfu Yang,Kun Yao et al.
Jinrong Wang et al.
Background: Bladder cancer (BCa) is the most common genitourinary malignancy and causes substantial economic losses worldwide. Recent studies suggest overexpression of circCD2AP in BCa, but its mechanistic contributions t...