Nano drug delivery system based on natural cells and derivatives for ischemic stroke treatment [0.03%]
基于天然细胞和衍生物的纳米药物输送系统在缺血性脑卒中治疗中的应用
Wei Lv,Yijiao Liu,Shengnan Li et al.
Wei Lv et al.
Ischemic stroke (IS) ranks as a leading cause of death and disability globally. The blood-brain barrier (BBB) poses significant challenges for effective drug delivery to brain tissues. Recent decades have seen the development of targeted na...
Regional and local burden of psoriasis in China, 1990-2021: Findings from the Global Burden of Disease Study 2021 [0.03%]
中国1990-2021年银屑病疾病负担的区域和地方特征：全球疾病负担研究2021结果
Haihui Yang,Bin Yang,Pengpeng Ye et al.
Haihui Yang et al.
Efficacy and safety of using an enteral immunonutrition formula in the enhanced recovery after surgery protocol for Chinese patients with gastrointestinal cancers undergoing surgery: A randomized, open-label, multicenter trial (healing trial) [0.03%]
围手术期免疫营养粉剂用于中国消化道肿瘤患者加速康复的疗效和安全性研究：一项随机、开放标记、多中心临床试验（愈进研究）
Jianchun Yu,Gang Xiao,Yanbing Zhou et al.
Jianchun Yu et al.
Auxiliary diagnosis of hyperpigmented skin diseases using multimodal deep learning [0.03%]
基于多模态深度学习的色素性皮肤病辅助诊断
Ting Li,Jingwei Zhang,Bowei Li et al.
Ting Li et al.
Diagnosis and treatment of colorectal liver metastases: Chinese expert consensus-based multidisciplinary team (2024 edition) [0.03%]
结直肠肝转移的诊断与治疗：中国专家共识版多学科诊疗（2024年版）
Wen Zhang,Xinyu Bi,Yongkun Sun et al.
Wen Zhang et al.
MASLD development: From molecular pathogenesis toward therapeutic strategies [0.03%]
MASLD发病机制研究及治疗策略探讨
Zhu Yang,Jiahui Zhao,Kexin Xie et al.
Zhu Yang et al.
Metabolic dysfunction-associated steatotic liver disease (MASLD) comprises a spectrum of liver injuries, including steatosis to steatohepatitis (MASH), liver fibrosis, cirrhosis, and relevant complications. The liver mainly comprises hepato...
MLL1 downregulation drives hair cell ferroptosis via mitochondrial and endoplasmic reticulum stress mechanisms through PERK-eIF2α-Atf4-Chop and PI3K/Akt-Lrp1 signaling pathway [0.03%]
MLL1低表达通过PERK-eIF2α-Atf4-Chop和PI3K/Akt-Lrp1信号通路驱动线粒体及内质网应激介导的听毛细胞铁死亡
Chang Liu,Siyu Qiu,Wen Li et al.
Chang Liu et al.
Background: Sensorineural hearing loss is characterized by irreversible hair cell (HC) degeneration. Ferroptosis, which is marked by the accumulation of reactive oxygen species and elevated levels of lipid peroxidation pr...
Critical role of mitochondrial dynamics in chronic respiratory diseases and new therapeutic directions [0.03%]
线粒体动力学在慢性呼吸系统疾病中的关键作用及新的治疗途径
Xiaomei Wang,Ziming Zhu,Haocheng Jia et al.
Xiaomei Wang et al.
Chronic obstructive pulmonary disease (COPD) and pulmonary hypertension (PH) are both chronic progressive respiratory diseases that cannot be completely cured. COPD is characterized by irreversible airflow limitation, chronic airway inflamm...
Global, regional, and national burden of neonatal encephalopathy due to birth asphyxia and trauma, 1990-2019 [0.03%]
1990至2019年全球、区域和国家范围内的新生儿脑病负担：由于出生窒息及创伤所致
Xiaoshan Ji,Zhongmeng Xiong,Ting Peng et al.
Xiaoshan Ji et al.
Background: Neonatal encephalopathy (NE) due to birth asphyxia and trauma has become the second leading cause of global neonatal and under-5 deaths. However, comprehensive data on the global NE burden is scarce. This stud...
Perioperative dexmedetomidine reduces the risk of postoperative complications in high-risk patients undergoing non-cardiac surgery: A randomized controlled trial [0.03%]
术前术后使用右美托咪定可降低非心脏手术高危患者术后并发症的风险：一项随机对照试验
Zhaoting Meng,Ting Ding,Wei Zhao et al.
Zhaoting Meng et al.
Background: Dexmedetomidine may suppress the surgery-induced inflammatory response, which is considered the underlying mechanism of postoperative complications. This study was designed to investigate whether perioperative...