Novel compound heterozygous variants in lectin mannose-binding 2-like gene identified in a Chinese autosomal recessive mental retardation-52 (MRT52) patient with phenotype expansion [0.03%]
在一名具有新表型的中国常染色体隐性精神发育不全-52患者中鉴定出lectin, mannose binding 2-like基因新型复合杂合变异
Cong Zhou,Xing Wei,Yuanyuan Xiao et al.
Cong Zhou et al.
Primary malignant bone tumors incidence, mortality, and trends in China from 2000 to 2015 [0.03%]
中国原发恶性骨肿瘤的发病、死亡及流行趋势（2000-2015年）
Yunfeng Xi,Liying Qiao,Buqi Na et al.
Yunfeng Xi et al.
Background: Primary malignant bone tumors are uncommon, and their epidemiological features are rarely reported. We aimed to study the incidence and death characteristics of bone tumors from 2000 to 2015. ...
Molecular classification of small cell lung cancer subtypes: Characteristics, prognostic factors, and clinical translation [0.03%]
小细胞肺癌亚型的分子分型：特征、预后因素和临床转化
Hanfei Guo,Wenqian Li,Ye Guo et al.
Hanfei Guo et al.
Small cell lung cancer (SCLC) is a highly malignant tumor with a very poor prognosis; therefore, more effective treatments are urgently needed for patients afflicted with the disease. In recent years, emerging molecular classifications base...
Junxian Wen,Nanze Yu,Xiao Long et al.
Junxian Wen et al.
Association of interpregnancy interval and risk of adverse pregnancy outcomes in woman by different previous gestational ages [0.03%]
不同孕龄的妊娠间隔与不良妊娠结局的关系
Peiran Chen,Yi Mu,Zheng Liu et al.
Peiran Chen et al.
Background: With an increasing proportion of multiparas, proper interpregnancy intervals (IPIs) are urgently needed. However, the association between IPIs and adverse perinatal outcomes has always been debated. This study...
Genome-wide methylation profiling identified methylated KCNA3 and OTOP2 as promising diagnostic markers for esophageal squamous cell carcinoma [0.03%]
全基因组甲基化谱分析鉴定出KCNA3和OTOP2甲基化作为食管鳞癌有潜力的诊断标志物
Yan Bian,Ye Gao,Chaojing Lu et al.
Yan Bian et al.
Background: Early detection of esophageal squamous cell carcinoma (ESCC) can considerably improve the prognosis of patients. Aberrant cell-free DNA (cfDNA) methylation signatures are a promising tool for detecting ESCC. H...
Jichao Bian,Yang Liu,Xiaowei Zhao et al.
Jichao Bian et al.
Osteosarcoma (OS) is the most common primary malignant bone tumor that more commonly occurs in children and adolescents. The most commonly used treatment for OS is surgery combined with chemotherapy, but the treatment outcomes are typically...
Transcriptome dysregulation in hyper-progressive disease samples with immune checkpoint blockade [0.03%]
免疫检查点抑制剂治疗中超进展型样本的转录组失调
Dan Xue,Tengteng Zhu,Hongguang Lin et al.
Dan Xue et al.
Tricuspid regurgitation following pacemaker implantation for bradycardia: a two-year study comparing different pacing strategies [0.03%]
心动过缓起搏治疗后三尖瓣反流两年不同起搏策略的比较研究
Xiaofei Li,Xiaohan Fan,Qian Wang et al.
Xiaofei Li et al.
Redefining human health: physical wellbeing, mental wellbeing, social wellbeing, and environmental wellbeing [0.03%]
重新定义人类健康：生理、心理、社交及环境福祉
Chen Wang,Simiao Chen,Ruitai Shao et al.
Chen Wang et al.