Single-cell multi-omics reveals compartmentalized heterogeneity, clonal dynamics, and B cell interplay of CD8+ T cell subsets in anti-NMDAR encephalitis [0.03%]
单细胞多组学揭示抗NMDAR脑炎中CD8+t细胞亚群的区室异质性、克隆动力学和B细胞相互作用
Sisi Li,Xiang Hu,Yi Yang et al.
Sisi Li et al.
Update on the global, regional, and national burden of pancreatic cancer: Insights from the Global Burden of Disease 2021 Study [0.03%]
全球、区域和国家胰腺癌负担的最新情况：来自2021年全球疾病负担研究的新见解
Huijuan Cheng,Guodong Sun,Hao Chen et al.
Huijuan Cheng et al.
Redefining multiple myeloma treatment: Advances, challenges, and future directions in immunotherapy [0.03%]
多发性骨髓瘤治疗的免疫治疗进展、挑战和未来方向
Chengcheng Fu,Yingying Zhai,Lingzhi Yan et al.
Chengcheng Fu et al.
Multiple myeloma (MM) is a hematological malignancy that poses significant treatment challenges due to its heterogeneity and propensity for relapse and progression. In the last two decades, the therapeutic landscape of MM has changed dramat...
Microenvironment crosstalk and immune evasion of circulating tumor cells: From mechanism to clinical significance [0.03%]
循环肿瘤细胞的微环境互作和免疫逃逸：从机制到临床意义
Shi Chen,Sirui Zhang,Ying Shi et al.
Shi Chen et al.
Circulating tumor cells (CTCs), shed from the primary malignancies, are regarded as the "seeds" of tumor metastasis. They employ sophisticated strategies to evade immune detection during blood circulation by engaging with various blood comp...
Challenges of minimally invasive treatment for acute obstructive suppurative cholangitis in elderly patients [0.03%]
老年患者急性梗阻性化脓性胆管炎微创治疗的挑战
Zongming Zhang,Jiahong Dong,Xiaodong He et al.
Zongming Zhang et al.
lncRNA PVT1 mediates bile acid-induced gastric intestinal metaplasia via a miR-34b-5p/HNF4α positive feedback loop [0.03%]
长链非编码RNA PVT1通过miR-34b-5p/HNF4α正反馈环介导胆汁酸诱导的胃肠上皮化生
Kexin Lin,Nuo Yao,Xingyu Zhao et al.
Kexin Lin et al.
Background: Bile acids (BAs) facilitate the progression of gastric intestinal metaplasia (GIM). Long non-coding RNAs (lncRNAs) dysregulation was observed along with the initiation of gastric cancer. However, how lncRNAs f...
Hanchen Liu,Yun Chen,Jing Zhang et al.
Hanchen Liu et al.
Alzheimer's disease (AD) is the most common cause of dementia and is a growing public health challenge. Neuroinflammation has been proposed as a prominent pathological feature of AD and has traditionally been attributed to the innate immune...
Immunotherapy and radiotherapy: An effective combination in cancer treatment [0.03%]
免疫治疗和放射治疗在癌症治疗中的有效结合
Xuewei Li,Chen Wang,Haiou Yang et al.
Xuewei Li et al.
Immunotherapy has been widely used in cancer treatment in recent years and functions by stimulating the immune system to kill tumor cells. Radiation therapy (RT) uses radiation to induce DNA damage and kill tumor cells. However, this activa...
Bidirectional crosstalk of the gut-liver axis in metabolic dysfunction-associated steatotic liver disease [0.03%]
代谢功能异常相关脂肪性肝病的肠肝轴双向串扰
Juan Zhang,Xin Tong,Wei Lin et al.
Juan Zhang et al.
Association between blood glucose indicators and metabolic diseases in the Chinese population: A national cross-sectional study [0.03%]
中国成人血糖指标与代谢性疾病的关系：一项全国性横断面研究
Lijun Tian,Cihang Lu,Di Teng et al.
Lijun Tian et al.
Background: Studies on the impact of blood glucose indicators on metabolism remain relatively scarce. The aim of this study was to investigate the associations between blood glucose indicators and metabolic disorders in C...