Electroacupuncture enhances CSPCs proliferation in an FGFR4-mediated manner to ameliorate osteoarthritis-associated pain and cartilage degeneration [0.03%]
Shu Zhao,Liang Zhang,Ban Feng et al.
Shu Zhao et al.
Background: Osteoarthritis (OA) is an age-related degenerative joint disease for which there are no effective therapies. Although electroacupuncture (EA) has emerged as a potentially effective therapeutic intervention for...
Ferroptosis-driven metabolic reprogramming in macrophages: Reshaping glucose utilization landscapes [0.03%]
Yasheng Deng,Yafang Zheng,Qian Zhou et al.
Yasheng Deng et al.
Ferroptosis, an iron-dependent form of programmed cell death, has attracted significant attention in the field of immunometabolism. Macrophages, which are key immune cells, undergo metabolic reprogramming and polarization, influencing disea...
Yingyu Pan,Panduo Zhaxi,Zhen Yu et al.
Yingyu Pan et al.
Effect of circulating exosomal miRNA-122-3p on metabolic dysfunction-associated steatotic liver disease through impairing FGFR4 expression [0.03%]
Wei Wang,Lina Ma,Ying Chen et al.
Wei Wang et al.
Background: In metabolic dysfunction-associated steatotic liver disease (MASLD), exosome-encapsulated miRNAs mediate intercellular signaling pathways that drive dysregulated lipid metabolism, inflammation, and fibrosis. H...
Manli Wang,Xiaoqian Zhai,Jiayao Li et al.
Manli Wang et al.
Over the past decades, significant progress has been made in cancer treatment, including chemotherapy, targeted therapy, and more recently, immunotherapy. However, only a limited number of patients achieve cure with these therapies. A major...
Safety and feasibility of robot-assisted telesurgery at a distance of 5000 kilometers [0.03%]
远程机器人遥手术的可行性和安全性研究(两地相距约5000公里)
Wen Dong,Xiong Chen,Wang He et al.
Wen Dong et al.
Infusion of immunity- and matrix-regulatory cells as a protective strategy against premature death triggered by severe sleep deprivation [0.03%]
注射免疫和基质调节细胞作为保护严重睡眠剥夺引起过早死亡的策略
Zongren Hou,Kailun Liu,Can Li et al.
Zongren Hou et al.
Jingjing Liang,Linhua Yang,Ruijuan Zhang
Jingjing Liang
Lifestyle intervention reduces type 2 diabetes incidence among young women with previous gestational diabetes: A randomized controlled trial [0.03%]
生活方式干预可降低先前患有妊娠糖尿病的年轻女性发生2型糖尿病的风险:一项随机对照试验
Gang Hu,Huikun Liu,Weiqin Li et al.
Gang Hu et al.
Background: Women with a history of gestational diabetes mellitus (GDM) are at increased risk of developing type 2 diabetes later in life. This study evaluated whether lifestyle intervention can reduce the risk of type 2 ...