Association between self-reported sensory impairments and low cognitive performance in older adults: A cross-sectional study based on National Health and Nutrition Examination Survey (NHANES) [0.03%]
基于全国健康与营养调查的横断面研究：老年人感知能力障碍与认知表现之间的关联
Lu He,Yuansheng Rao,Jianhong Wang et al.
Lu He et al.
Background: Early identification of risk factors is vital for the control of cognitive degenerative diseases, and sensory impairments could be potential candidate indicators. ...
Tar DNA binding protein 43, a proteinopathy with preference for olfactory structures in COVID-19 subjects [0.03%]
Covid-19患者中TARDNA结合蛋白43对嗅觉结构的优先作用
Sylwia Libard,Irina Alafuzoff
Sylwia Libard
Background: Olfactory impairment (OI) is an early symptom of neurodegenerative diseases (ND) and COVID-19 infection. Proteinopathies associated with ND include amyloid-β (Aβ), hyperphosphorylated τ (HPτ), α-synuclein...
Vitreous STMN2 levels reflect TDP-43-associated neurodegeneration in postmortem eyes and brains [0.03%]
玻璃体STMN2水平反映死后眼睛和与TDP-43相关的脑神经退行性病变
Surya V Pulukuri,Elizabeth E Spurlock,Fatima Tuz-Zahra et al.
Surya V Pulukuri et al.
Stathmin-2 (STMN2) levels decline in brains with transactive response DNA binding protein-43 (TDP-43) inclusions. TDP-43-related changes could extend to ocular structures, although vitreous STMN2 levels remain uncharacterized. This explorat...
Cognitive reserve as a predictor of cognitive decline, but not age of diagnosis in patients with possible young-onset Alzheimer's disease: An underexplored population [0.03%]
认知储备作为预测可能的年轻发病阿尔茨海默病患者认知下降而非诊断年龄的指标：一个被忽视的人群
Anat Marmor,Zeev Meiner,Shlomzion Kahana Merhavi et al.
Anat Marmor et al.
Background: The cognitive reserve (CR) theory aims to explain the disparity often observed between brain damage and its clinical manifestation. Objective:...
Comprehensive descriptive analysis of large Alzheimer's disease patient cohorts [0.03%]
阿尔茨海默病患者大队列的全面描述性分析
Ehsan Yaghmaei,Attallah Dillard,Mohammadreza Rezaei et al.
Ehsan Yaghmaei et al.
Background: Precise estimates of the prevalence of Alzheimer's disease (AD), the distribution of demographic characteristics, comorbidities, treatment plans, insurance types, cost of treatment and survival probabilities a...
Adaptation and validations of Amsterdam instrumental activities of daily living questionnaire-short version for Peru [0.03%]
荷兰乐器活动日常生活问卷简表在秘鲁的修订及验证研究
Rosa Montesinos,Gregory Brown,José Huilca et al.
Rosa Montesinos et al.
Background: Instrumental Activities of Daily Living (IADL) are key indicators of functional decline in dementia, but culturally adapted tools for Latin America are scarce. ...
Comparison of microglial cell population expansion in the Tg344-AD rat and APPSWE/PS1ΔE9 mouse model of Alzheimer's disease [0.03%]
阿尔茨海默病tg344-ad大鼠和app swe / ps1Δe9小鼠模型中微胶质细胞群增殖的比较研究
Julie Hansen,Rowda Mohamed,Laura Ilkjær et al.
Julie Hansen et al.
Background: Chronic microglial activation is a key characteristic of Alzheimer's disease (AD). In mouse models of AD, microglial activation is considered associated with microglial cell population expansion. ...
Sensory processing assessment in Alzheimer's disease and related dementias: Opportunities for improved care [0.03%]
阿尔茨海默病及相关痴呆的感觉评估：改善护理的机会
Elizabeth K Rhodus,Lauren E Robinson,Celeste Roberts et al.
Elizabeth K Rhodus et al.
Background: Sensory stimulation, such as sight, hearing, and smell influence healthy neurological processing evident by the growing literature which demonstrates that sensory loss increases Alzheimer's disease and related...
Real-world diagnosis and management of mild cognitive impairment and Alzheimer's disease dementia in the United Kingdom [0.03%]
英国轻度认知障碍和阿尔茨海默病的诊断与治疗状况
Caroline S Casey,Niraj Patel,Simona Z Vasileva-Metodiev et al.
Caroline S Casey et al.
Background: Timely diagnosis of Alzheimer's disease (AD) remains challenging in the United Kingdom and improvements are needed with the introduction of new therapies. ...
Harnessing team science in dementia research: Insights from the Alzheimer's disease research group in South Carolina [0.03%]
痴呆症研究中的团队科学：南卡罗来纳州阿尔茨海默病研究小组的见解
Sayema Akter,Eric Mishio Bawa,Nicholas Riccardi et al.
Sayema Akter et al.
Alzheimer's disease and related dementias (ADRD) are complex and rapidly growing public health challenges that require integrative, collaborative approaches. To meet this need, the Alzheimer's Disease Research Center (ADRC) of South Carolin...