Inactivation of BACE2 stimulates release of endothelin-1 from human brain microvascular endothelial cells [0.03%]
BACE2失活可刺激人脑微血管内皮细胞释放内皮素-1
Tongrong He,Zvonimir S Katusic
Tongrong He
Beta-site amyloid precursor protein cleaving enzyme 2 (BACE2) is one of the most downregulated genes in the brain capillary endothelial cells derived from patients with Alzheimer's disease (AD). Endothelin-1 (ET-1) significantly contributes...
A bibliometric and systematic review of the global impact of air pollution on Alzheimer's disease: Insights from cohort studies [0.03%]
全球空气污染对阿尔茨海默病影响的计量学和系统性综述：队列研究的新见解
Faezeh Jahedi,Gholamreza Goudarzi,Mehdi Ahmadi et al.
Faezeh Jahedi et al.
Background: Emerging evidence highlights the potential role of environmental factors, particularly air pollution, in the development and progression of Alzheimer's disease (AD). Air pollutants may contribute to neurodegen...
Bibliometric analysis of pathological mechanisms in Alzheimer's disease: Applications based on mouse models [0.03%]
阿尔茨海默病病理机制的文献计量分析：基于小鼠模型的应用研究
Jinjiang Li,Zhaoxiong Lin,Yufei Niu et al.
Jinjiang Li et al.
Background: Alzheimer's disease (AD) is a progressive neurodegenerative disorder marked by memory loss and cognitive decline. Animal models play a key role in exploring its pathophysiological mechanisms. ...
Potential link of high fat diet and mRNA expression of Alzheimer's disease-related genes in the enteric mucosa of a rat model of Alzheimer's disease [0.03%]
高脂饮食与阿尔茨海默病模型大鼠肠黏膜中相关基因的mRNA表达之间的潜在联系
Kuppan Gokulan,Kumari Karn,Sumit Sarkar et al.
Kuppan Gokulan et al.
Background: High-fat diet (HFD) consumption is linked to Alzheimer's disease (AD). Identifying changes in the mRNA expression due to the ingestion of HFD in the intestine-often called the second brain due to its dense ent...
Retinal manifestations and their diagnostic significance in Alzheimer's disease [0.03%]
阿尔茨海默病的视网膜表现及其诊断意义
Surabhi D Abhyankar,Karis Little,Alan Stitt et al.
Surabhi D Abhyankar et al.
Alzheimer's disease (AD) is a neurodegenerative condition manifesting as cognitive decline, memory deterioration, and behavioral alterations. Late-onset AD accounts for most diagnosed cases, with the onset of symptoms usually occurring afte...
Executive functioning and processing speed as predictors of global cognitive decline in Alzheimer's disease [0.03%]
执行功能和处理速度作为阿尔茨海默病全球认知衰退的预测因素
John P Haran,A M Barrett,YuShuan Lai et al.
John P Haran et al.
Background: Better cognitive tools to predict disease progression in mild cognitive impairment (MCI) and Alzheimer's disease (AD) are needed. Objective: ...
Diagnostic and inclusion criteria in Alzheimer's disease clinical trials: A systematic review of the past decade [0.03%]
阿尔茨海默病临床试验的诊断和纳入标准：过去十年的系统综述
Yumei Liu,Siyan Chen,Sha Li et al.
Yumei Liu et al.
Background: Dementia, mainly caused by Alzheimer's disease (AD), is a leading cause of mortality and disability in the elderly. However, inconsistencies in diagnostic and inclusion criteria challenge the design and compar...
A qualitative study of music-based intervention use for Alzheimer's disease in elder care communities [0.03%]
养老机构中针对阿尔茨海默病患者开展音乐疗法的定性研究
Benjamin J Hess,Ava Zatloukal,Jasmine M Taylor et al.
Benjamin J Hess et al.
Background: Because music-based interventions (MBIs) are not standard of care for Alzheimer's disease and Alzheimer's disease related dementias (AD/ADRD), it is likely that the application of them in different care commun...
Measurement invariance of the Research Attitudes Questionnaire in an age and ethnically diverse, community-dwelling sample [0.03%]
在种族和年龄多样化且居住在社区的样本中测量研究态度问卷的不变性
Diane Carol Gooding,C Malik Boykin,Carol Ann Van Hulle et al.
Diane Carol Gooding et al.
Background: The Research Attitudes Questionnaire (RAQ), developed to predict individuals' willingness to participate, is often used in Alzheimer's Disease and related dementia research. ...
Causal associations and shared genetic etiology between neurodegenerative diseases and constipation [0.03%]
神经退行性疾病与便秘之间的因果关系及共通的遗传病因
Weidong Sun,Anlong Zhu,Hanman Chang et al.
Weidong Sun et al.
Background: There is increasing evidence suggesting a correlation between neurodegenerative diseases (NDDs) and constipation; however, their genetic relationship and causal mechanisms remain inadequately elucidated. ...