Regular monitoring of SARS-CoV-2 carriage and antibody levels against the virus helped maintain social interactions for Alzheimer's disease residents in a Belgian nursing home during the pandemic [0.03%]
在大流行期间定期监测SARS-CoV-2载量和抗体水平有助于比利时一家养老院的阿尔茨海默病患者保持社交互动
Amandine Tytgat,Anh Nguyet Diep,Florence Flamme et al.
Amandine Tytgat et al.
Background: People suffering from Alzheimer's disease and related disorders (ADRD) were severely impacted by the COVID-19 pandemic, both physically and mentally. ...
Neurofilament light (NfL) chain levels predict clinical decline in Alzheimer's disease: A systematic review and meta-analysis [0.03%]
神经丝轻链(NfL)水平可预测阿尔茨海默病的临床衰退：系统评价和meta分析
Kim Thomas,Paul Spin,Nikita Sir et al.
Kim Thomas et al.
Background: Regulatory approval of new investigational Alzheimer's disease (AD) therapies could be accelerated if reasonably likely surrogate endpoints could be used. Neurofilament light chain (NfL) has potential utility ...
Progesterone induction of tau phosphorylation during the differentiation of human embryonic stem cells into neuroectodermal rosettes [0.03%]
孕酮诱导人胚胎干细胞分化为人神经外胚层囊泡中的tau蛋白磷酸化现象
Prashob Porayette,Maria M Kaltcheva,George Perry et al.
Prashob Porayette et al.
Background: Tau phosphorylation is associated with neuronal division and differentiation in the fetal brain, in neuroblastoma cells, in the hibernating brains of ground squirrels and black bears, and in post-mitotic neuro...
Integrating repetitive transcranial magnetic stimulation and Mediterranean diet for cognitive and anxiety improvement in early Alzheimer's disease: A case report and literature review [0.03%]
重复经颅磁刺激联合地中海饮食改善早期阿尔茨海默病认知及焦虑状况的病例报告和文献复习
Yumei Liu,Lin Zhu,Zian Pei et al.
Yumei Liu et al.
A 52-year-old male with early-stage Alzheimer's disease and long-standing anxiety received 30 repetitive transcranial magnetic stimulation sessions over 8 months and 20-month Mediterranean diet intervention. Neuropsychological assessments [...
Brexpiprazole: Pioneering medication for managing agitation in Alzheimer's disease [0.03%]
用于治疗阿尔茨海默病激越的创新药物brexpiprazole
Ayesha Shaukat,Rumaisa Riaz,Nawal Khaliq et al.
Ayesha Shaukat et al.
Alzheimer's disease poses intricate challenges, affecting cognition and behavior, notably marked by agitation. The FDA's approval of brexpiprazole, an atypical antipsychotic, stands as a milestone, representing the first treatment for Alzhe...
Effects of a person-centered music-based intervention in the rehabilitation of older adults with mild to moderate dementia [0.03%]
基于个人中心的音乐干预对轻至中度痴呆老年人康复的影响
Sara Santini,Alessandra Merizzi,Maria Joao Azevedo et al.
Sara Santini et al.
Background: With the progressive population aging, dementia is reaching epidemic dimensions worldwide. Non-pharmacological music-based interventions can have a positive impact on the rehabilitation of older adults with de...
Exploration of the potential role of plasma lipoprotein molecules in late-onset Alzheimer's disease among the Chinese population [0.03%]
探索血浆脂蛋白分子在中国人群晚发性阿尔茨海默病中潜在作用的研究
Shitao Wang,Guoshuai Luo,Qingqing Zhao et al.
Shitao Wang et al.
Background: Evidence suggests that lipoprotein metabolism play a crucial role in Alzheimer's disease (AD). However, their involvement in late-onset AD (LOAD) remains unclear. ...
Using machine learning to identify risk factors for Alzheimer's disease among older adults in the United States: The role of chronic and behavioral health [0.03%]
利用机器学习识别美国老年人阿尔茨海默病风险因素：慢性病和行为健康的作用
Md Roungu Ahmmad,Emran Hossain,Md Tareq Ferdous Khan et al.
Md Roungu Ahmmad et al.
Background: The interactions between behavioral disturbances, chronic diseases, and Alzheimer's disease (AD) risk are not fully understood, particularly in the context of the COVID-19 pandemic. ...
Comorbidities and apolipoprotein E genotypes of patients with mild cognitive impairment in transition to Alzheimer's disease [0.03%]
从轻度认知障碍发展为阿尔茨海默病患者的伴随疾病及载脂蛋白E基因型分析
Mingfei Li,Ying Wang,Lewis Kazis et al.
Mingfei Li et al.
Background: Three common chronic diseases in the elderly: diabetes, hypertension, and hypercholesterolemia, associate with mild cognitive impairment (MCI) and Alzheimer's disease (AD). ...
Adverse reproductive outcomes and future risk of incident dementia: The modifying effect of genetic susceptibility [0.03%]
不良生殖结局与未来患痴呆症风险的关系：遗传易感性的调节作用
Qiaoqiao Xu,Chengzhe Tao,Sijia Dai et al.
Qiaoqiao Xu et al.
Background: Adverse reproductive outcomes (AROs) in women can lead to the occurrence of a variety of diseases later in life. However, research on AROs and dementia risk in women has not been reported. ...