Metabolic factors, gut microbiota, and cognitive performance: Mendelian randomization analysis [0.03%]
代谢因素、肠道微生物群和认知表现：孟德尔随机化分析
Erhan Yu,Yi Zhang,Jiahui Chen et al.
Erhan Yu et al.
Background: The associations between several metabolic factors, gut microbiota (GM), and cognitive performance have not been clearly identified. This study investigates their associations and GM's mediating effects. ...
Psychometric evaluation of the Alzheimer's Disease Knowledge Scale in Ecuadorian university students [0.03%]
艾尔伯特病知识量表在厄瓜多尔大学生中的心理测量学评价研究
José Alejandro Valdevila Figueira,Andrés Ramírez,Xavier Rodrigo Yambay-Bautista et al.
José Alejandro Valdevila Figueira et al.
Background: Alzheimer's disease (AD) is the leading cause of dementia worldwide, with rising prevalence, high costs, and significant impact in Ecuador. Awareness and validated tools like the Alzheimer's Disease Knowledge ...
Amyloid marker levels and the risk of developing cerebral small vessel disease: A Mendelian randomization study [0.03%]
淀粉样标志物水平与脑小血管病发病风险之间的关系：一项孟德尔随机化研究
Zhuoya Wang,Kailin Xia,Xin Huang et al.
Zhuoya Wang et al.
Background: Previous observational studies have suggested a potential association between amyloid marker levels and the risk of developing cerebral small vessel disease (CSVD), but this relationship remains incompletely u...
Defining healthy longevity and dementia prevention campaigns have been tied to the ability to work [0.03%]
界定健康长寿和痴呆预防活动与工作能力息息相关
Bilal Irfan,Roberto Sirvent,Hana Abbasian et al.
Bilal Irfan et al.
Contemporary dementia-prevention campaigns inherit a century-old coupling of health with economic productivity. By framing "healthy longevity" as the capacity to sustain waged labor, they cast risk reduction as a personal duty to insure fut...
Clarifying blood-based brain-derived neurotrophic factor measurement in Alzheimer's disease research: A call for pre-analytic standardization [0.03%]
阿尔茨海默病研究中基于血液的脑源性神经营养因子测量的规范化前标准迫在眉睫：呼唤明确化和标准化
Ted Ks Ng
Ted Ks Ng
The study by Kueck et al. rigorously addresses the complex pre-analytical and biological confounds underlying blood-based brain-derived neurotrophic factor (BDNF) measurement in Alzheimer's disease (AD) research. By directly comparing plate...
José Alejandro Valdevila Figueira,Andrés Ramírez,Xavier Rodrigo Yambay-Bautista et al.
José Alejandro Valdevila Figueira et al.
Background: This study examines the prevalence and incidence of dementia in Ecuador, with a focus on understanding demographic and social factors associated with increased risk. Data were obtained from the Institute of Ne...
Global, regional, and national burdens of early-onset Alzheimer's disease and other dementias in women, 1990 to 2021 [0.03%]
1990至2021年全球、区域和国家妇女早发性阿尔茨海默病和其他痴呆的疾病负担
Fanshun Zhao,Yongze Li,Chenju Yi et al.
Fanshun Zhao et al.
Background: Alzheimer's disease and other dementias disproportionally impacts women. Novel treatment makes understanding of early-onset cases unprecedentedly important. ...
Assessment of microstructural changes in white matter hyperintensities in aging and mild cognitive impairment revealed by advanced diffusion MRI [0.03%]
利用先进的扩散磁共振成像评估老化和轻度认知障碍中高信号白质病变的微结构变化
Maurizio Bergamino,Megan R Nelson,Elizabeth Keeling et al.
Maurizio Bergamino et al.
Background: White matter hyperintensities (WMHs) are common in older adults and appear as abnormal signal on T2-weighted or fluid-attenuated inversion recovery (FLAIR) magnetic resonance imaging (MRI). They are often link...
A preliminary study on the effect of quantified cranial osteopathic manipulation on wild-type and transgenic rat models of Alzheimer's disease [0.03%]
颅骨生物力学量化手法作用于老年痴呆模型大鼠的初步研究
De&#x;Yana Hines,Hope Tobey,Patrick Dugan et al.
De&#x;Yana Hines et al.
Alzheimer's disease is a chronic progressive neurodegenerative disorder that impairs the meningeal lymphatics, glymphatic system, and compartmental fluid exchange, leading to a decline in cognitive function. Due to the lack of non-pharmacol...
John Cheung-Yuen Chan
John Cheung-Yuen Chan
Ad-model rationale: The contributing factors of Alzheimer's disease are cerebral vessel disease, insulin resistance, hypometabolism, oxidative stress, abnormal-protein aggregation, and inflammation. Brain insulin resistan...