Interictal Epileptiform Activity in the Foramen Ovale Electrodes of a Frontotemporal Dementia Patient [0.03%]
frontal颞顶交界区脑电癫痫样放电1例报告
András Horváth,Anna Szűcs,Gábor Barcs et al.
András Horváth et al.
Frontotemporal dementia (FTD) is a frequent cause of cognitive decline. While epilepsy is an important comorbidity of Alzheimer's disease, we lack studies on its presence in FTD. We report on an FTD patient with transient, short-term change...
Imaging Biomarkers in Alzheimer's Disease: A Practical Guide for Clinicians [0.03%]
阿尔茨海默病影像生物标志指南：临床医师实用手册
Nasim Sheikh-Bahaei,Seyed Ahmad Sajjadi,Roido Manavaki et al.
Nasim Sheikh-Bahaei et al.
Although recent developments in imaging biomarkers have revolutionized the diagnosis of Alzheimer's disease at early stages, the utility of most of these techniques in clinical setting remains unclear. The aim of this review is to provide a...
Survival Curves and Behavioral Profiles of Female 3xTg-AD Mice Surviving to 18-Months of Age as Compared to Mice with Normal Aging [0.03%]
与正常衰老小鼠相比18月龄的3xTg-AD雌性小鼠的存活曲线和行为特征
Virginia Torres-Lista,Mónica De la Fuente,Lydia Giménez-Llort
Virginia Torres-Lista
New evidence reveals a high degree of heterogeneity in Alzheimer's disease (AD) clinical and temporal patterns, supporting the existence of several subgroups of patients. Prognosticators of end-of-life dementia specific to elderly patients ...
Pravat K Mandal,Krity Kansara,Aroma Dabas
Pravat K Mandal
Alzheimer's disease (AD) is a highly debilitating neurodegenerative disease with no cure to date. Emerging evidence indicates aberrations of the primary inhibitory neurotransmitter GABA in the frontal, parietal and temporal cortices, and hi...
Md Rashidur Rahman,Afsana Tajmim,Mohammad Ali et al.
Md Rashidur Rahman et al.
Alzheimer's disease (AD) is a complex neurological disorder with economic, social, and medical burdens which is acknowledged as leading cause of dementia marked by the accumulation and aggregation of amyloid-β peptide and phosphorylated ta...
Aluminum Should Now Be Considered a Primary Etiological Factor in Alzheimer's Disease [0.03%]
铝应被视为阿尔茨海默病的主要病因因素
Christopher Exley
Christopher Exley
In this paper, I have summarized the experimental and largely clinical evidence that implicates aluminum as a primary etiological factor in Alzheimer's disease. The unequivocal neurotoxicity of aluminum must mean that when brain burdens of ...
When New Technology is an Answer for Old Problems: The Use of Videoconferencing in Cognitive Aging Assessment [0.03%]
当新技术能解决旧问题时：视频会议在认知老化评估中的应用
Teresa Costa Castanho,Nuno Sousa,Nadine Correia Santos
Teresa Costa Castanho
People living with cognitive impairment and dementia require regular screening of their symptomatology and needs. Brief cognitive screening is crucial for assessing these conditions. Such screening can give health professionals a snapshot o...
Whole-Day Gait Monitoring in Patients with Alzheimer's Disease: A Relationship between Attention and Gait Cycle [0.03%]
阿尔茨海默病患者的全天步行监测：注意与步态周期的关系
Maya Higuma,Nobuo Sanjo,Hiroshi Mitoma et al.
Maya Higuma et al.
Background: Gait impairment in patients with Alzheimer's disease (AD) and its relationship with cognitive function has been described, but reports of gait analysis in AD in daily living are limited. Objective: To investigate whether gait pa...
Alzheimer's Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database [0.03%]
美国食品药品监督管理局不良事件数据库中的阿尔茨海默病和氟替卡松鼻喷剂不良事件报告
Steven Lehrer,Peter H Rheinstein
Steven Lehrer
Background: Studies of Alzheimer's disease suggest that neuroinflammation or deranged brain wound healing may be a cause of some cases. But a placebo controlled study showed no effect at all on Alzheimer's disease of low ...
Decreased Expression of Sulfatase 2 in the Brains of Alzheimer's Disease Patients: Implications for Regulation of Neuronal Cell Signaling [0.03%]
阿尔茨海默病患者大脑中的硫酸盐酶2表达降低：对神经细胞信号传导调节的意义
Rosebud O Roberts,Yoo Na Kang,Chunling Hu et al.
Rosebud O Roberts et al.
Background: The human sulfatase 1 (SULF1) and sulfatase 2 (SULF2) genes modulate cell signaling and homeostasis in many tissues. Gene expression analyses have implicated SULF2 in disease pathogenesis, including Alzheimer'...