Driving Safety of Cognitively-Impaired Drivers Based on Near Collisions in Naturalistic Driving [0.03%]
基于自然驾驶中的近碰撞事故的轻度认知障碍驾驶员驾车安全研究
Mojtaba Moharrer,Shuhang Wang,Jennifer D Davis et al.
Mojtaba Moharrer et al.
Background: Controlled naturalistic driving for examining impacts of cognitive impairment on driving safety is rare. Objective: Evaluat...
Five Hundred Patients with Memory Loss in One Clinic in India: Does the Prevalence Vary Between Communities? [0.03%]
印度一个诊所的500名记忆障碍患者：不同社区中的患病率是否有所不同？
Vijay Chandra,Veer Singh Mehta
Vijay Chandra
This observational study reports on the cause of memory loss in 500 consecutive patients. It confirms the previously reported finding in a smaller sample of 100 patients. There have been several publications suggesting that the prevalence o...
Erratum: Relative Efficacy of a Nutritional Intervention on Cognitive Performance Across the Adult Lifespan and During Early Cognitive Decline [0.03%]
有关营养干预对成人一生中认知表现的相对疗效及早期认知衰退期间疗效的勘误声明
Thomas B Shea,Ruth Remington
Thomas B Shea
[This corrects the article DOI: 10.3233/ADR-190124.]. © 2019 – IOS Press and the authors. All rights reserved.
Published Erratum
Journal of Alzheimer's disease reports. 2019 Dec 13;3(1):311. DOI:10.3233/ADR-199001 2019
Maryam Vasefi,Mackenzie Hudson,Ehsan Ghaboolian-Zare
Maryam Vasefi
Neurocognitive disorders, such as Alzheimer's disease (AD), affect millions of people worldwide and are characterized by cognitive decline. Human and animal studies have shown that chronic immune response and inflammation are important fact...
Nature's Derivative(s) as Alternative Anti-Alzheimer's Disease Treatments [0.03%]
天然衍生物作为治疗阿尔茨海默病的替代药物
Anuja Sharma,Yatender Kumar
Anuja Sharma
Alzheimer's disease (AD), the 'Plague of Twenty-First Century,' is a crippling neurodegenerative disease that affects a majority of the older population globally. By 2050, the incidence of AD is expected to rise to 135 million, while no tre...
Reduced Acoustic Startle Response and Prepulse Inhibition in the Tg4-42 Model of Alzheimer's Disease [0.03%]
阿尔茨海默病Tg4-42模型的听性惊跳反应降低和前脉冲抑制现象
Marius E Sichler,Maximilian J Löw,Eva M Schleicher et al.
Marius E Sichler et al.
Sensorimotor deficits have been described in several neuropsychiatric disorders including Alzheimer's disease. The aim of the present study was to evaluate possible sensorimotor gating deficits in the Tg4-42 mouse model of Alzheimer's disea...
Curcumin Downregulates GSK3 and Cdk5 in Scopolamine-Induced Alzheimer's Disease Rats Abrogating Aβ40/42 and Tau Hyperphosphorylation [0.03%]
姜黄素通过下调GSK3和Cdk5来抑制东莨菪碱诱导的AD大鼠Tau蛋白及Aβ40/42高磷酸化作用
Tushar Kanti Das,Piyali Jana,Swarup Kumar Chakrabarti et al.
Tushar Kanti Das et al.
Alzheimer's disease (AD) is the most common form of dementia. Extracellular amyloid-β (Aβ) aggregation and tau hyperphosphorylation are the key drivers of AD. Glycogen synthase kinase 3 (GSK3) and cyclin dependent kinase 5 (Cdk5) have bee...
Relative Efficacy of a Nutritional Intervention on Cognitive Performance Across the Adult Lifespan and During Early Cognitive Decline [0.03%]
营养干预对一生中成人认知表现的相对疗效及其在早期认知衰退中的疗效
Thomas B Shea,Ruth Remington
Thomas B Shea
A nutritional supplement has maintained or improved cognitive performance for healthy adults and individuals with mild cognitive impairment (MCI). Performance varied between 93 healthy adults aged 18-73 years versus 43 aged 75-85 years and ...
Mental Disorders in Young Adults from Families with the Presenilin-1 Gene Mutation E280A in the Preclinical Stage of Alzheimer's Disease [0.03%]
早发型阿尔茨海默病基因突变携带者家系中年轻成人的情绪和精神障碍：临床前期阶段的精神疾病症状特征研究
Arvey Camilo Villalba,Jenny García,Claudia Ramos et al.
Arvey Camilo Villalba et al.
Background: There are forms of Alzheimer's disease (AD) that have an autosomal dominant inheritance pattern; one of them is caused by the E280A mutation in the gene that codes for Presenilin-1 (PSEN1). Studying families o...
Global Clinical Dementia Rating Score of 0.5 May Not Be an Accurate Criterion to Identify Individuals with Mild Cognitive Impairment [0.03%]
全球临床痴呆评定量表评分0.5可能无法准确鉴别轻度认知障碍患者
Kenji Wada-Isoe,Takashi Kikuchi,Yumi Umeda-Kameyama et al.
Kenji Wada-Isoe et al.
Many studies use the global clinical dementia rating (CDR) of 0.5 as a criterion for mild cognitive impairment, but past studies have not fully discussed its validity. The authors developed the ABC Dementia Scale (ABC-DS) to accurately moni...