Neurobiological Pathways Linking Acute Mental Stress to Impairments in Executive Function in Individuals with Coronary Artery Disease [0.03%]
急性心理应激导致冠心病患者执行功能障碍的神经生物学路径研究
Kasra Moazzami,Matthew T Wittbrodt,Bruno B Lima et al.
Kasra Moazzami et al.
Background: Individuals with coronary artery disease (CAD) have worse executive function compared to the general population but the mechanisms are unknown. ...
APOE ɛ 4 Allele and Financial Capacity Performance in Mild Alzheimer's Disease: A Pilot Study [0.03%]
轻度阿尔茨海默病患者APOE ε4基因型与金融能力表现的关系：一项前瞻性研究
Vaitsa Giannouli,Magda Tsolaki
Vaitsa Giannouli
This study aims to explore a little investigated topic, i.e., whether the presence of the APOE eɛ4 allele in patients with a diagnosis of mild Alzheimer's disease (AD) can influence financial capacity. Twenty-eight elders with mild AD carr...
How Comorbidity Reflects on Cerebrospinal Fluid Biomarkers of Neurodegeneration in Aging [0.03%]
共病对衰老相关神经退行性病变脑脊液生物标志物的影响研究
Henri Zenuni,Piergiorgio Grillo,Giulia Maria Sancesario et al.
Henri Zenuni et al.
Systemic comorbidity precipitates the risk for dementia. To comprehend the underlying mechanisms into a therapeutic perspective, we analyzed how comorbidity affects neurodegeneration-related cerebrospinal fluid (CSF) biomarkers of 55 cognit...
Porphyromonas Gingivalis May Seek the Alzheimer's Disease Brain to Acquire Iron from Its Surplus [0.03%]
牙龈卟啉单胞菌可能寻求富含铁的阿尔茨海默病大脑以获得铁元素供给自身生长
Ingar Olsen
Ingar Olsen
Iron accumulates in the brain of subjects with Alzheimer's disease (AD). Here it promotes the aggregation of amyloid-β plaques in which it is abundant. Iron induces amyloid-β neurotoxicity by damaging free radicals and causing oxidative s...
Obesity and Brain Vulnerability in Normal and Abnormal Aging: A Multimodal MRI Study [0.03%]
肥胖与正常及异常衰老中的脑部脆弱性：一项多模态磁共振成像研究
Manmohi D Dake,Matteo De Marco,Daniel J Blackburn et al.
Manmohi D Dake et al.
Background: How the relationship between obesity and MRI-defined neural properties varies across distinct stages of cognitive impairment due to Alzheimer's disease is unclear. ...
Shining the Light on the MotionWatch8 Light Sensor for Sleep and Aging Research: What Can We Measure and What Are We Missing? [0.03%]
MotionWatch 8光照传感器在睡眠和衰老研究中的应用：我们可以测量什么？我们又忽视了什么？
Ryan S Falck,Rachel A Crockett,Jennifer C Davis et al.
Ryan S Falck et al.
Background: Poor sleep is common among older adults at risk for dementia and may be due to circadian dysregulation. Light is the most important external stimulus to the circadian clock and bright light therapy (BLT) has b...
Breast Cancer, Alzheimer's Disease, and APOE4 Allele in the UK Biobank Cohort [0.03%]
英国生物样本库中APOE4等位基因与乳腺癌和阿尔茨海默病的关系
Steven Lehrer,Peter H Rheinstein
Steven Lehrer
Background: Cognitive problems are common in breast cancer patients. The apolipoprotein E4 (APOE4) gene, a risk factor for Alzheimer's disease (AD), may be associated with cancer-related cognitive decline. ...
Sleep and Tau Pathology in Vietnam War Veterans with Preclinical and Prodromal Alzheimer's Disease [0.03%]
越南战争退伍军人中睡眠与tau病理在阿尔茨海默病前驱期和临床前期的相互作用
Murray Andrews,Ryan Ross,Atul Malhotra et al.
Murray Andrews et al.
Background: The increasing prevalence of Alzheimer's disease (AD) and lack of effective medications has led to a need to identify modifiable risk factors as targets for interventions. ...
Effects of Self-Identification as a Caregiver on Expectations of Public Stigma of Alzheimer's Disease [0.03%]
照顾者自我认同对阿兹海默症公众污名预期效果的影响
Shana D Stites,Emily A Largent,Rebecca Johnson et al.
Shana D Stites et al.
Background: As a result of caring for a person with dementia, caregivers of persons with Alzheimer's disease (AD) may be uniquely aware of public stigma for persons with AD. ...
Diagnosis of Alzheimer's Disease in Developed and Developing Countries: Systematic Review and Meta-Analysis of Diagnostic Test Accuracy [0.03%]
发达国家和发展中国家阿尔茨海默病的诊断：诊断准确性检测的系统评价和meta分析
Miguel A Chávez-Fumagalli,Pallavi Shrivastava,Jorge A Aguilar-Pineda et al.
Miguel A Chávez-Fumagalli et al.
Background: The present systematic review and meta-analysis of diagnostic test accuracy summarizes the last three decades in advances on diagnosis of Alzheimer's disease (AD) in developed and developing countries. ...