Does Informant-Based Reporting of Cognitive Decline Correlate with Age-Adjusted Hippocampal Volume in Mild Cognitive Impairment and Alzheimer's Disease? [0.03%]
基于举报的认知衰退与轻度认知障碍和阿尔茨海默病的年龄调整海马体积相关吗？
Marwan Sabbagh,Justin Miller,Stephen Jones et al.
Marwan Sabbagh et al.
Background: Informant-based measures are effective screening tools for cognitive impairment. The Alzheimer's Questionnaire (AQ) is a subjective, informant-based measure that detects amnestic mild cognitive impairment (aMC...
Incorporating a Usual Care Comparator into a Study of Meditation and Music Listening for Older Adults with Subjective Cognitive Decline: A Randomized Feasibility Trial [0.03%]
将冥想和音乐聆听与一般护理进行比较以治疗主观认知下降的老年人：随机可行性试验
Kim E Innes,Caitlin Montgomery,Terry Kit Selfe et al.
Kim E Innes et al.
Background: Recent studies suggest meditation and music listening (ML) may improve cognitive and psychosocial outcomes in adults with subjective cognitive decline (SCD). However, lack of a usual care group has limited con...
Biological Features of Reversion from Mild Cognitive Impairment to Normal Cognition: A Study of Cerebrospinal Fluid Markers and Brain Volume [0.03%]
由轻度认知障碍恢复至正常认知的生物学特征：脑脊液标志物和脑容量研究
Kamyar Moradi,Shahriar Faghani,AmirHussein Abdolalizadeh et al.
Kamyar Moradi et al.
Background: Mild cognitive impairment (MCI) is a transitional condition between normal cognition and dementia. Although a significant proportion of the population with MCI experience reversion to normal cognition, it is s...
Mario F Mendez
Mario F Mendez
Although Alzheimer's disease (AD) is primarily a neurocognitive disorder, it also results in prominent neuropsychiatric symptoms (NPS). Much literature has investigated the NPS of apathy and depression in association with AD, but relatively...
A Virtual Reality-Based Screening Test for Cognitive Impairment in Small Vessel Disease [0.03%]
基于虚拟现实的认知障碍筛查小血管病患者
Hatice Limoncu,Hatice Eraslan Boz,Stelios Zygouris et al.
Hatice Limoncu et al.
Background: There is a need for new practical tools to assess the cognitive impairment of small vessel disease (SVD) patients in the clinic. Objective: ...
Amyloid-β Oligomers Induce Only Mild Changes to Inhibitory Bouton Dynamics [0.03%]
淀粉样蛋白寡聚体仅引起抑制性突触微小变化
Marvin Ruiter,Christine Lützkendorf,Jian Liang et al.
Marvin Ruiter et al.
The amyloid-β protein precursor is highly expressed in a subset of inhibitory neuron in the hippocampus, and inhibitory neurons have been suggested to play an important role in early Alzheimer's disease plaque load. Here we investigated bo...
Online Personalised Training in Memory Strategies for Everyday (OPTIMiSE) Program for Older Adults with Cognitive Concerns: Pilot Study Protocol [0.03%]
针对认知障碍老年人的在线记忆策略训练计划（OPTIMiSE）试点研究方案
Kerryn E Pike,Carl I Moller,Christina Bryant et al.
Kerryn E Pike et al.
Memory interventions for older adults with cognitive concerns result in improved memory performance and maintenance of cognitive health. These programs are typically delivered face-to-face, which is resource intensive and creates access bar...
Betahydroxybutyrate Consumption in Autopsy Brain Tissue from Alzheimer's Disease Subjects [0.03%]
阿尔茨海默病患者脑组织中β-羟基丁酸的消耗
Russell H Swerdlow,Mony J de Leon,David L Marcus
Russell H Swerdlow
Background: Alzheimer's disease (AD) features perturbed brain glucose utilization, which could contribute to brain bioenergetic failure. This led some to consider using ketone bodies to enhance AD brain bioenergetics and ...
Age-Related Chronic Diseases and Alzheimer's Disease in Texas: A Hispanic Focused Study [0.03%]
德克萨斯州的年龄相关慢性疾病和阿尔茨海默病：以西班牙裔人群为重点的研究
Shyam Sheladia,P Hemachandra Reddy
Shyam Sheladia
The emergence of age-related chronic diseases within the United States has led to the direct increase of Alzheimer's disease (AD) as well as other neurological diseases which ultimately contribute to the development of dementia within the g...
SPON1 Is Associated with Amyloid-β and APOE ε4-Related Cognitive Decline in Cognitively Normal Adults [0.03%]
SPON1与认知正常的成年人中的淀粉样蛋白-Aβ和APOEε4相关的认知下降有关
Shane Fernandez,Samantha C Burnham,Lidija Milicic et al.
Shane Fernandez et al.
Background: Genetic variation in Spondin-1, specifically rs11023139, has been associated with reduced rates of cognitive decline in individuals with Alzheimer's disease. ...