José Alejandro Valdevila Figueira,Andrés Ramírez,Xavier Rodrigo Yambay-Bautista et al.
José Alejandro Valdevila Figueira et al.
Background: This study examines the prevalence and incidence of dementia in Ecuador, with a focus on understanding demographic and social factors associated with increased risk. Data were obtained from the Institute of Ne...
Global, regional, and national burdens of early-onset Alzheimer's disease and other dementias in women, 1990 to 2021 [0.03%]
1990至2021年全球、区域和国家妇女早发性阿尔茨海默病和其他痴呆的疾病负担
Fanshun Zhao,Yongze Li,Chenju Yi et al.
Fanshun Zhao et al.
Background: Alzheimer's disease and other dementias disproportionally impacts women. Novel treatment makes understanding of early-onset cases unprecedentedly important. ...
Assessment of microstructural changes in white matter hyperintensities in aging and mild cognitive impairment revealed by advanced diffusion MRI [0.03%]
利用先进的扩散磁共振成像评估老化和轻度认知障碍中高信号白质病变的微结构变化
Maurizio Bergamino,Megan R Nelson,Elizabeth Keeling et al.
Maurizio Bergamino et al.
Background: White matter hyperintensities (WMHs) are common in older adults and appear as abnormal signal on T2-weighted or fluid-attenuated inversion recovery (FLAIR) magnetic resonance imaging (MRI). They are often link...
A preliminary study on the effect of quantified cranial osteopathic manipulation on wild-type and transgenic rat models of Alzheimer's disease [0.03%]
颅骨生物力学量化手法作用于老年痴呆模型大鼠的初步研究
De&#x;Yana Hines,Hope Tobey,Patrick Dugan et al.
De&#x;Yana Hines et al.
Alzheimer's disease is a chronic progressive neurodegenerative disorder that impairs the meningeal lymphatics, glymphatic system, and compartmental fluid exchange, leading to a decline in cognitive function. Due to the lack of non-pharmacol...
John Cheung-Yuen Chan
John Cheung-Yuen Chan
Ad-model rationale: The contributing factors of Alzheimer's disease are cerebral vessel disease, insulin resistance, hypometabolism, oxidative stress, abnormal-protein aggregation, and inflammation. Brain insulin resistan...
Reimagining dementia screening: A stakeholder-informed perspective on artificial intelligence, digital biomarkers, and real-world implementation [0.03%]
重新构想痴呆症筛查：利益相关者视角下的人工智能、数字生物标志物和现实世界实施
Kevin Mekulu,Faisal Aqlan,Hui Yang
Kevin Mekulu
The approval of disease-modifying treatments for Alzheimer's disease demands a rethinking of cognitive screening. Drawing on over 180 stakeholder interviews from the NSF National I-Corps program, this perspective highlights barriers in curr...
Combined 64-channel EEG and PET evaluation of lecanemab efficacy: Two case reports [0.03%]
兰卡奈单抗疗效的联合评估（64通道脑电图和正电子发射断层扫描）：两例报告
Xichun Wang,Yumei Liu,Shuhan Fan et al.
Xichun Wang et al.
Lecanemab, an anti-amyloid-β (Aβ) monoclonal antibody, has shown potential in slowing Alzheimer's disease (AD) progression. We report divergent responses in two AD patients with similar backgrounds following lecanemab treatment. Subject 1...
Rural-urban differences in modifiable dementia risk factors among U.S. populations aged 45 years or older [0.03%]
美国45岁及以上人群可改变的痴呆症风险因素的城乡差异
Zhigang Xie,Jiamin Hu,Sericea Stallings-Smith et al.
Zhigang Xie et al.
Background: Alzheimer's disease and related dementias (ADRD) have become a significant public health concern, and the burden is disproportionately concentrated in rural areas. ...
Risk factors and gender disparity of cognitive impairment among cancer and neurological diseases regarding rural West Texas [0.03%]
关于德克萨斯州西部农村地区癌症和神经疾病患者的认知障碍风险因素及性别差异研究
Hafiz Khan,Lamourdia Dayamba,Aamrin Rafiq
Hafiz Khan
Background: The prevalence of Alzheimer's disease or dementia is rising among the elderly population in the United States and globally. Sociodemographic, cancer, and neurological disorders are associated with cognitive im...
Comparative analysis of PET and multiparametric MRI biomarkers in Alzheimer's disease continuum cohort [0.03%]
阿尔茨海默病谱系队列中PET和多模态MRI生物标志物的比较分析
Chileka Chiyanika,Nga Yan Chan,Wanting Liu et al.
Chileka Chiyanika et al.
Background: Non-invasive biomarkers are key to early Alzheimer's disease (AD) detection. Multiparametric MRI and advanced imaging offer promising, accessible tools for identifying AD-related changes, supporting timely dia...