Salience Network Functional Connectivity Mediates Association Between Social Engagement and Cognition in Non-Demented Older Adults: Exploratory Investigation [0.03%]
探索性研究:社交参与和非痴呆老年人认知之间的关系由突显网络功能连接性介导
Patrick J Pruitt,Jessica S Damoiseaux,Benjamin M Hampstead et al.
Patrick J Pruitt et al.
Background: Social engagement has beneficial effects during cognitive aging. Large-scale cognitive brain network functions are implicated in both social behaviors and cognition. ...
Curve Walking Reveals More Gait Impairments in Older Adults with Mild Cognitive Impairment than Straight Walking: A Kinect Camera-Based Study [0.03%]
基于Kinect相机的步态研究:曲线行走比直线行走更能揭示出轻度认知障碍老年人的步态异常
Mahmoud Seifallahi,James E Galvin,Behnaz Ghoraani
Mahmoud Seifallahi
Background: Mild cognitive impairment (MCI) can be an early sign of Alzheimer's disease and other types of dementia detectable through gait analysis. Curve walking, which demands greater cognitive and motor skills, may be...
Measures of Awareness in Alzheimer's Disease and Clinical Differences Between Groups with Preserved, Impaired, and Absent Awareness [0.03%]
阿尔茨海默病的觉知度量及其临床差异性
Isabel Barbeito Lacerda,Maria Alice Tourinho Baptista,Tatiana Belfort et al.
Isabel Barbeito Lacerda et al.
Background: Awareness is a heterogeneous construct that requires accurate assessment. There is no consensus on the best methodology for capturing the phenomenon, thus leading to inconsistent results in this area. ...
Seasonal Variations in Vitamin D Levels and the Incident Dementia Among Older Adults Aged ≥60 Years in the UK Biobank [0.03%]
英国生物样本库中老年人维生素D水平的季节性变化与老年痴呆症发病的关系研究(≥60岁)
Jiahao Liu,Eddy Roccati,Yutong Chen et al.
Jiahao Liu et al.
Background: Limited knowledge exists regarding the association between dementia incidence and vitamin D insufficiency/deficiency across seasons. Objective...
Retinal and Cortical Visual Processing Dysfunction in a Case of Mild Cognitive Impairment with Lewy Bodies: A Case Report [0.03%]
路易体轻度认知障碍病例的视网膜和皮质视觉处理功能障碍:案例报告
Giulia Perini,Matteo Cotta Ramusino,Francesca Conca et al.
Giulia Perini et al.
The prodromal stage of Lewy body dementia includes a mild cognitive impairment with visual processing and/or attention-executive deficits. A clinical presentation with progressive visual loss is indeed seldom reported and can be misleading ...
Discriminant Potential of the Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog) in Greek Older Adults with Subjective Cognitive Decline and Mild Cognitive Impairment [0.03%]
希腊老年人主观认知下降和轻度认知障碍的阿尔茨海默病评估量表-认知亚量表(ADAS-Cognition)的判别潜力
Marianna Tsatali,Despina Moraitou,Moses Gialaouzidis et al.
Marianna Tsatali et al.
Background: Alzheimer's Disease Assessment Scale Cognitive Subscale (ADAS-Cog) is a widely used screening tool for detecting older adults with Alzheimer's disease among their cognitively healthy peers. A previous study in...
Transcriptomic Analysis of Alzheimer's Disease Pathways in a Pakistani Population [0.03%]
巴基斯坦人群的阿尔茨海默病途径的转录组分析
Tanmoy Mondal,Zarish Noreen,Christopher A Loffredo et al.
Tanmoy Mondal et al.
Background: Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder that is most prevalent in elderly individuals, especially in developed countries, and its prevalence is now increasing in developing coun...
Changes in Brain Structure and Function in a Multisport Cohort of Retired Female and Male Athletes, Many Years after Suffering a Concussion: Implications for Neuroplasticity and Neurodegenerative Disease Pathogenesis [0.03%]
多项目前运动员退休多年后脑结构和功能的变化:对神经可塑性和神经退行性疾病发病机制的影响
Michael Turner,Antonio Belli,Rudolph J Castellani
Michael Turner
Background: Cumulative effects of traumatic brain injury is of increasing concern, especially with respect to its role in the etiology and pathogenesis of neurodegenerative diseases, such as Alzheimer's disease, Parkinson...
Dissecting Alzheimer's Disease Risk in Asian American Elders: A Classification and Regression Tree Approach [0.03%]
基于分类和回归树方法分析美国亚裔老年人阿尔茨海默病的患病风险因素
Sung Seek Moon,Lindsey Anderson,Jinyu Liu et al.
Sung Seek Moon et al.
Background: Alzheimer's disease (AD) poses a growing public health challenge, particularly with an aging population. While extensive research has explored the relationships between AD, socio-demographic factors, and cardi...
Dimethyl Fumarate Exerts a Neuroprotective Effect by Enhancing Mitophagy via the NRF2/BNIP3/PINK1 Axis in the MPP+ Iodide-Induced Parkinson's Disease Mice Model [0.03%]
苹果酸二甲酯通过NRF2/BNIP3/PINK1轴增强线粒体自噬从而对MPP+碘诱导的帕金森小鼠模型产生神经保护作用
Poojitha Pinjala,Kamatham Pushpa Tryphena,Amrita Kulkarni et al.
Poojitha Pinjala et al.
Background: Parkinson's disease (PD) is a progressive neurodegenerative disorder linked to the loss of dopaminergic neurons in the substantia nigra. Mitophagy, mitochondrial selective autophagy, is critical in maintaining...