Circulating Cell Free DNA and DNA Double-Strand Breakage in Alzheimer's Disease [0.03%]
阿尔茨海默病患者的循环细胞游离DNA及DNA双链断裂损伤
Michelle Nguyen,Colby Wood,Andres Rios et al.
Michelle Nguyen et al.
Alzheimer's disease (AD) is an age-related neurodegenerative disease that is characterized by memory loss and multiple cognitive impairments. AD is pathologically characterized by age-dependent accumulation of amyloid-β protein and the pho...
A Comparative Evaluation of Error Processing Performance and its Relationship with Cognitive Function in Patients with Alzheimer's Disease, Individuals with Mild Cognitive Impairment, and Normal Controls Using the Event-Related Potentials [0.03%]
事件相关电位研究阿尔茨海默病患者、轻度认知障碍个体和正常被试的错误加工性能及其与认知功能的关系
Mohammad Hedayatjoo,Mehdi Tehrani-Doost,Zahra Vahabi et al.
Mohammad Hedayatjoo et al.
Background: Some pathological changes occur in patients with Alzheimer's disease (AD) prior to the onset of clinical symptoms. Objective: ...
Gallic Acid Alleviates Cognitive Impairment by Promoting Neurogenesis via the GSK3β-Nrf2 Signaling Pathway in an APP/PS1 Mouse Model [0.03%]
没食子酸通过GSK3β-Nrf2信号通路促进神经发生从而改善APP/PS1双转基因小鼠模型的认知障碍作用及机制研究
Yu Ding,Jinrong He,Fanli Kong et al.
Yu Ding et al.
Background: Neuronal loss occurs early and is recognized as a hallmark of Alzheimer's disease (AD). Promoting neurogenesis is an effective treatment strategy for neurodegenerative diseases. Traditional Chinese herbal medi...
Spirituality for Social Isolation in a Patient with Cognitive Impairment: A Case Report [0.03%]
认知障碍患者的社会隔离精神照护案例报告
Akshay P Padala,Parameshwaran Ramakrishnan,Christina G Crawford
Akshay P Padala
Background: Social isolation is very common and has increased during the COVID-19 pandemic. Objective: To study if spiritual reconnecti...
ChatGPT as a Diagnostic Aid in Alzheimer's Disease: An Exploratory Study [0.03%]
作为阿尔茨海默病诊断辅助的ChatGPT：一项探索性研究
Mohamad El Haj,Claire Boutoleau-Bretonnière,Karim Gallouj et al.
Mohamad El Haj et al.
Background: The potential of ChatGPT in medical diagnosis has been explored in various medical conditions. Objective: We assessed wheth...
Intelligent Alzheimer's Diseases Gene Association Prediction Model Using Deep Regulatory Genomic Neural Networks [0.03%]
基于深度调控基因组神经网络的智能阿尔茨海默病关联基因预测模型
M Rohini,S Oswalt Manoj,D Surendran
M Rohini
Alzheimer's disease (AD) is an illness that affects the nervous system, leading to a loss in cognitive and logical abilities. Gene regulatory expressions, which are the complex language exhibited by DNA, serve several functionalities, inclu...
What Threshold of Amyloid Reduction Is Necessary to Meaningfully Improve Cognitive Function in Transgenic Alzheimer's Disease Mice? [0.03%]
斑块减少到什么程度能够显著改善唐氏小鼠的认知功能？
Anita Singh,Matthew Maker,Jayant Prakash et al.
Anita Singh et al.
Background: Amyloid-β plaques (Aβ) are associated with Alzheimer's disease (AD). Pooled assessment of amyloid reduction in transgenic AD mice is critical for expediting anti-amyloid AD therapeutic research. ...
Is Effective Recruitment Strategy Critical to Assess Brain Cognitive Function of Super Agers in Rural West Texas [0.03%]
有效的招聘策略对评估德克萨斯州西部农村超级老年人脑认知功能的评判是否关键？
Malcolm Brownell,Ujala Sehar,Sudhir Kshirsagar et al.
Malcolm Brownell et al.
Our commentary aims to elucidate the importance of participant recruitment strategy in healthy brain aging study, particularly in rural West Texas, where more than 50% of the population are Hispanics and Latinos. The objective of our health...
Associations of Serum Liver Function with Cerebral Blood Flow in Patients with Alzheimer's Disease [0.03%]
阿尔茨海默病患者血清肝功能与脑血流的关系研究
Hao Wang,Lin Shi,Shimei Luo et al.
Hao Wang et al.
Background: Increasing evidence suggests that both amyloid-β metabolism disorders in the liver and cerebral hypoperfusion play an important role in the pathogenesis of Alzheimer's disease (AD). However, the relevance of ...
Effect of Internet Use on Cognitive Function of Middle-Aged and Elderly Adults in China: Evidence from China Family Panel Studies [0.03%]
基于CFPS数据的中国中老年人互联网使用与认知功能关系研究
Xuefei Xia,Pingqiao Yuan,Xue Zhao et al.
Xuefei Xia et al.
Background: The development and popularization of the Internet provides an important opportunity to advance national strategies for healthy aging, particularly the impact of the Internet on cognitive function in middle-ag...