Identification of Cinnamein, a Component of Balsam of Tolu/Peru, as a New Ligand of PPARα for Plaque Reduction and Memory Protection in a Mouse Model of Alzheimer's Disease [0.03%]
从托卢香胶/秘鲁香胶中鉴定出cinnamein并将其确定为新型PPARα配体,可减少阿尔茨海默病小鼠模型中的斑块形成和保护记忆力
Mary McKay,Sukhamoy Gorai,Ramesh K Paidi et al.
Mary McKay et al.
Background: Despite intense investigations, no effective treatment is yet available to reduce plaques and protect memory and learning in patients with Alzheimer's disease (AD), the most common neurodegenerative disorder. ...
Kenichi Hashiguchi,Ryota Kobayashi,Daichi Morioka et al.
Kenichi Hashiguchi et al.
Identifying the coexistence of Lewy body (LB) pathology with Alzheimer's disease (AD) in clinical practice is important in the era of anti-amyloid-β antibody therapy. However, few studies have predicted the presence of comorbid LB patholog...
Creating Cultural and Lifestyle Awareness About Dementia and Co-morbidities [0.03%]
创建有关痴呆及其共病的文化和生活意识
Malcolm Brownell,Ujala Sehar,Upasana Mukherjee et al.
Malcolm Brownell et al.
Dementia is a major health concern in society, particularly in the aging population. It is alarmingly increasing in ethnic minorities such as Native Americans, African Americans, Hispanics/Latinos, and to some extent Asians. With increasing...
Erratum to: Seasonal Variations in Vitamin D Levels and the Incident Dementia Among Older Adults Aged ≥60 Years in the UK Biobank [0.03%]
维生素D水平的季节性变化与英国生物银行老年受试者痴呆症发病风险的相关性校正说明
[This corrects the article DOI: 10.3233/ADR-230077.]. © 2024 – The authors. Published by IOS Press.
Published Erratum
Journal of Alzheimer's disease reports. 2024 May 7;8(1):791-792. DOI:10.3233/ADR-249002 2024
Social Determinants of Health, Risk and Resilience against Alzheimer's Disease and Related Dementias: The Healthy Brain Initiative [0.03%]
阿尔茨海默病及相关痴呆症的健康大脑倡议:影响因素、风险和应对能力
Lilah M Besser,Kyle Edwards,Nina-Simone Lobban et al.
Lilah M Besser et al.
Background: Few studies have investigated associations between perceived social determinants of health (SDOH) and Alzheimer's disease and related dementia (ADRD) biomarkers or between SDOH and resilience against ADRD. ...
Promoting Trustworthiness of Science: Reproducing and Verifying Agarwal et al.'s (2022) Findings Through Collaborative Endeavors [0.03%]
推动科研可信赖:合作再现与验证阿加瓦尔等(2022)的研究成果
Yasaman Jamshidi-Naeini,Nicolas Escobar Velasquez,Lilian Golzarri-Arroyo et al.
Yasaman Jamshidi-Naeini et al.
Clinical Evidence for GLP-1 Receptor Agonists in Alzheimer's Disease: A Systematic Review [0.03%]
葡萄糖依赖性促胰岛素多肽类似物治疗阿尔茨海默病的临床证据:系统综述
Yulin Liang,Vincent Doré,Christopher C Rowe et al.
Yulin Liang et al.
Background: Alzheimer's disease (AD) is the most common cause of dementia. While preclinical studies have shown benefits of glucagon-like peptide 1 receptor agonists (GLP-1 RA) in targeting core AD pathology, clinical stu...
Predictive Modeling Using a Composite Index of Sleep and Cognition in the Alzheimer's Continuum: A Decade-Long Historical Cohort Study [0.03%]
基于阿尔茨海默病谱系的睡眠和认知综合指数预测建模:一项十年长期历史队列研究
Xianfeng Yu,Shuqing Deng,Junxin Liu et al.
Xianfeng Yu et al.
Background: Sleep disturbances frequently affect Alzheimer's disease (AD), with up to 65% patients reporting sleep-related issues that may manifest up to a decade before AD symptoms. ...
Cognitive Impairment in the Post-Acute Phases of COVID-19 and Mechanisms: An Introduction and Narrative Review [0.03%]
新冠病毒肺炎急性期后的认知障碍及其机制:介绍与叙述性综述
Weiye Wang,Ruxin Cui,Luming Leng et al.
Weiye Wang et al.
Cognitive impairment is a primary manifestation of neurological symptoms associated with COVID-19 and may occur after disease resolution. Although cognitive impairment has been extensively reported in the literature, its duration and rate o...
Attitudes of Family Members and Caregivers Regarding Alzheimer's Disease Pre-Symptomatic Screening [0.03%]
阿尔茨海默病先证筛查的家庭成员和看护者的态度研究
Marina Makri,Akyllina Despoti,Birgit Teichmann et al.
Marina Makri et al.
Background: In recent years, studies have examined the acceptability and attitudes that influence the intention to early screen for Alzheimer's disease (AD) in the general population, older people, carers, and asymptomati...