Comparative Study of Risk Factors Associated with Normal Cognition and Cognitive Impairment in Rural West Elderly Texans [0.03%]
德克萨斯州西部农村地区老年人正常认知和认知障碍相关危险因素比较研究
Hafiz Khan,Fardous Farhana,Fahad Mostafa et al.
Hafiz Khan et al.
Background: Alzheimer's disease (AD) is related to one or more chronic illnesses, which may develop cognitive decline and dementia. Cognitive impairment is increasing, and public health officials must address risk factors...
Genome-Wide Mendelian Randomization Identifies Ferroptosis-Related Drug Targets for Alzheimer's Disease [0.03%]
全基因组孟德尔随机化鉴定阿尔茨海默病中铁死亡相关药物靶点
Ying Wang,Xinhua Song,Rui Wang et al.
Ying Wang et al.
Background: Alzheimer's disease (AD) currently lacks effective disease-modifying treatments. Recent research suggests that ferroptosis could be a potential therapeutic target. Mendelian randomization (MR) is a widely used...
Assessing the Potential of EEG in Early Detection of Alzheimer's Disease: A Systematic Comprehensive Review (2000-2023) [0.03%]
基于EEG的阿尔茨海默病早期检测研究进展：系统综述(2000-2023年)
Sharareh Ehteshamzad
Sharareh Ehteshamzad
Background: As the prevalence of Alzheimer's disease (AD) grows with an aging population, the need for early diagnosis has led to increased focus on electroencephalography (EEG) as a non-invasive diagnostic tool. ...
Use and Reuse of Animal Behavioral, Molecular, and Biochemical Data in Alzheimer's Disease Research: Focus on 3Rs and Saving People's Tax Dollars [0.03%]
阿尔茨海默病研究中动物行为、分子和生化数据的利用与再利用：侧重于3R伦理及节省纳税人的钱
Md Ariful Islam,Sudhir Kshirsagar,Arubala P Reddy et al.
Md Ariful Islam et al.
Several decades of research on cell and animal models contributed tremendously to understanding human diseases. Particularly, research on rodents and non-human primates revealed that animal research is a major and important component in bio...
Early-Stage Moderate Alcohol Feeding Dysregulates Insulin-Related Metabolic Hormone Expression in the Brain: Potential Links to Neurodegeneration Including Alzheimer's Disease [0.03%]
早期中度饮酒可调节大脑与代谢相关的胰岛素信号通路：或可联想到神经退行性疾病包括阿尔茨海默病
Yiwen Yang,Ming Tong,Suzanne M de la Monte
Yiwen Yang
Background: Alzheimer's disease (AD), one of the most prevalent causes of dementia, is mainly sporadic in occurrence but driven by aging and other cofactors. Studies suggest that excessive alcohol consumption may increase...
An Open-Label, Pilot Study of Daratumumab SC in Mild to Moderate Alzheimer's Disease [0.03%]
达托莫单抗皮下注射治疗轻度至中度阿尔茨海默病的开放标签、试点研究
Marc L Gordon,Erica Christen,Lynda Keehlisen et al.
Marc L Gordon et al.
We conducted a small, open-label, pilot study of daratumumab to explore target engagement, safety, and potential efficacy in patients with mild to moderate Alzheimer's disease. Daratumumab SC 1800 mg was given subcutaneously weekly for 8 we...
Screening for Cognitive Impairment in Movement Disorders: Comparison of the Montreal Cognitive Assessment and Quick Mild Cognitive Impairment Screen in Parkinson's Disease and Lewy Body Dementia [0.03%]
帕金森病和路易体痴呆患者认知障碍筛查：简易轻度认知障碍筛查与蒙特利尔认知评估量表的对比研究
Rónán O&#x;Caoimh,Mary J Foley,Suzanne Timmons et al.
Rónán O&#x;Caoimh et al.
Background: The Montreal Cognitive Assessment (MoCA) is recommended by the Movement Disorder Society for cognitive testing in movement disorders including Parkinson's disease (PD) and lewy body dementia. Few studies have ...
Knowledge, Awareness, and Perceived Threat Toward Alzheimer's Disease Among the Family Caregivers of Individuals with Chronic Physical Conditions in Bangladesh [0.03%]
孟加拉国慢性躯体疾病患者家属对阿尔茨海默病的知识、意识及感知威胁调查研究
Azaz Bin Sharif,Ishrat Jahan,A B M Nahid Hasan
Azaz Bin Sharif
Background: Alzheimer's disease (AD) is a growing public health concern affecting millions of individuals worldwide. This disease burden is exacerbated in countries like Bangladesh, where public awareness and knowledge ab...
The Crosstalk Between Amyloid-β, Retina, and Sleep for the Early Diagnosis of Alzheimer's Disease: A Narrative Review [0.03%]
淀粉样蛋白-β、视网膜和睡眠在阿尔茨海默病早期诊断中的相互作用：叙事性综述
Isaiah-Lorenzo De Guia,Shaun Eslick,Sharon L Naismith et al.
Isaiah-Lorenzo De Guia et al.
Alzheimer's disease (AD) is the most common type of dementia, which is characterised by progressive memory loss and accumulation of hallmark markers amyloid-β (Aβ) and neurofibrillary tangles in the diseased brain. The current gold standa...
Relationship Between Excessive Daytime Sleepiness and Caudate Nucleus Volume in Patients with Subjective Cognitive Decline: A Study from the SILCODE Using the Volbrain [0.03%]
主观认知下降患者日间过度嗜睡与尾状核体积关系的影像学研究——SILCODE项目VolBrain子研究
Ziqian Feng,Jiayu Wang,Lisi Xu et al.
Ziqian Feng et al.
Background: Excessive daytime sleepiness (EDS) and caudate nucleus volume alterations have been linked to Alzheimer's disease (AD), but their relationship remains unclear under the context of subjective cognitive decline ...