MRI-based mild cognitive impairment and Alzheimer's disease classification using an algorithm of combination of variational autoencoder and other machine learning classifiers [0.03%]
基于MRI的轻度认知障碍和阿尔茨海默病分类的一种变分自编码器和其他机器学习算法相结合的方法
Subhrangshu Bit,Pritam Dey,Arnab Maji;Alzheimer’s Disease Neuroimaging Initiative;Tapan K Khan
Subhrangshu Bit
Background: Correctly diagnosing mild cognitive impairment (MCI) and Alzheimer's disease (AD) is important for patient selection in drug discovery. Research outcomes on stage diagnosis using neuroimages combined with cere...
A progranulin gene deletion in frontotemporal lobar degeneration with corticobasal syndrome in a TREDEM case report [0.03%]
TREDEM病例报告中额颞叶退行性疾病伴皮质基底综合征的脯氨酸葡萄糖胺基因缺失
Maurizio Gallucci,Chiara Da Ronch,Matteo Bendini et al.
Maurizio Gallucci et al.
Background: Behavioral variant frontotemporal dementia usually presents with behavioral and personality changes, social disinhibition, apathy, and lack of empathy, and is characterized by atrophy of the frontal and tempor...
Articulatory and phonological performance in people with mild cognitive impairment and Alzheimer's disease: A scoping review [0.03%]
轻度认知障碍和阿尔茨海默病患者的发音和音系表现：范围综述
Maysa Cera,Paulo Henrique Ferreira Bertolucci,Nathani Cristine do Carmo Ramos et al.
Maysa Cera et al.
Background: Markers of phonological and articulatory processing, though at times difficult to identify, may be useful for the assessment of changes in the speech of people with mild cognitive impairment (MCI) and Alzheimer's disease (AD). O...
Synergistic activity of nootropic herbs as potent therapeutics for Alzheimer's disease: A cheminformatics, pharmacokinetics, and system pharmacology approach [0.03%]
具有治疗阿尔茨海默症潜能的智慧药物的协同作用：化讯、药代动力学以及系统药理学方法
Reiya Bosco Don Bosco,Johnson Retnaraj Samuel Selvan Christyraj,Beryl Vedha Yesudhason
Reiya Bosco Don Bosco
Background: Alzheimer's disease (AD) is a progressive neurodegenerative disorder, which subdues over 55 million people and finding a cure, still remains disenchanting. Indian medicinal herbs notably, Withania somnifera, B...
Centella asiatica improves cognitive function and alters the hippocampal metabolome of aged Tg2576 and wild-type mice [0.03%]
_centella asiatica改善了Tg2576和野生型大鼠的认知功能并改变了其海马体的代谢组_
Donald G Matthews,Mona Khorani,Gerd Bobe et al.
Donald G Matthews et al.
Background: Alzheimer's disease (AD) is a growing public health problem in the aging population, with limited treatment options. We previously reported that Centella asiatica herb water extract (CAW) attenuates cognitive ...
Critical evaluation of COSMIN scores in scales for mild cognitive impairment and Alzheimer's disease: A comprehensive review [0.03%]
COSMIN评分在轻度认知障碍和阿尔茨海默病量表中的关键评估：全面回顾
Xia Peng,Run-Chen Li,Ting Liang et al.
Xia Peng et al.
Background: Timely diagnosis and intervention of mild cognitive impairment (MCI) can delay the development of Alzheimer's disease (AD). Objective: The purpose of this study was to analyze assessment tools for cognitive function using the Co...
Astrocyte dysfunction alters GABAergic communication and ammonia metabolism in the streptozotocin-induced sporadic Alzheimer's disease model [0.03%]
星形胶质细胞功能障碍改变GABA能通讯和氨代谢在链脲佐菌素诱导的散发性阿尔茨海默氏病模型中
Éverton Carlos Brezolin,Vitor Gayger-Dias,Vanessa-Fernanda Da Silva et al.
Éverton Carlos Brezolin et al.
Background: In the sporadic model of Alzheimer's disease (AD), induced by intracerebroventricular streptozotocin (STZ) administration, cognitive impairment is accompanied by specific astrocytic changes in the hippocampus ...
Deep brain stimulation versus nonsurgical treatment for severe Alzheimer's disease: A long-term retrospective cohort study [0.03%]
深度脑刺激与非手术治疗对于严重阿尔茨海默病的对比：一项长期回顾性队列研究
Junpeng Xu,Bin Liu,Zhebin Feng et al.
Junpeng Xu et al.
Background: Severe Alzheimer's disease (AD) is characterized by significant neuropsychiatric symptoms and sleep disorders, with limited effectiveness of conservative drug treatments. Deep brain stimulation (DBS) offers a ...
Adamantia Koulouri,Anthony S Zannas
Adamantia Koulouri
Dementia encompasses a broad spectrum of neuropsychiatric disease states marked by cognitive impairments that interfere with day-to-day functioning. Most dementias are complex phenotypes that result from a genome-environment interplay. Epig...
Cardio and cerebrovascular diseases risk among Alzheimer's disease patients and racial/ethnic disparities, based on Hawaii Medicare data [0.03%]
基于夏威夷医疗保险数据的阿尔茨海默病患者中心血管和脑血管疾病风险及种族/民族差异性研究
Chathura Siriwardhana,Enrique Carrazana,Kore Liow et al.
Chathura Siriwardhana et al.
Background: Alzheimer's disease (AD) and cardiovascular and cerebrovascular diseases (CVD) are significant concerns among the elderly, sharing overlapping risk factors. Hawaii's unique demographic profile, characterized b...