Gut microbiome synthesizes important core metabolites to prevent cognitive decline and mitigate onset and progression of Alzheimer's disease [0.03%]
肠道微生物群合成重要的核心代谢物以防止认知能力下降，并减轻阿尔茨海默病的发生和发展
Nouf S Al-Abbas,Nehad A Shaer
Nouf S Al-Abbas
Background: This study explores how gut metabolites, produced through bacterial metabolism in the gut, influence neurological conditions like Alzheimer's disease (AD). Key metabolites such as succinate and short-chain fat...
A systematic study of molecular targets of cannabidiol in Alzheimer's disease [0.03%]
阿尔茨海默病中药物CBD作用分子靶标的系统研究
Nil Patil,Khushalika Patil,Mukul Jain et al.
Nil Patil et al.
Background: Alzheimer's disease (AD) is a prevalent, incurable, and chronic neurodegenerative condition characterized by the accumulation of amyloid-β protein (Aβ), disrupting various bodily systems. Despite the lack of...
Association between dementia, Alzheimer's disease, and liver cancer: A Mendelian randomization analysis [0.03%]
痴呆症、阿尔茨海默病与肝癌之间的关联性：梅纳随机分析法分析
Tianze Li,Jianwei Yi,Xuliang Hu et al.
Tianze Li et al.
Background: Epidemiological studies have indicated an inverse association between neurodegenerative diseases and cancer. However, the relationship between liver cancer and dementia, particularly Alzheimer's disease (AD), ...
Retinal vascular changes are associated with PET-based biomarkers of Alzheimer's disease: A pilot study [0.03%]
视网膜血管变化与基于PET的阿尔茨海默病生物标志物有关：初步研究
Kristie Hing Chi Leung,Victor T T Chan,Bonnie Yin Ka Lam et al.
Kristie Hing Chi Leung et al.
Background: Retina is a non-invasive channel for assessing changes in brain microvasculature, which has been implicated in the pathophysiology of Alzheimer's disease (AD). Previous studies revealed significant relationshi...
How to assess cognitive decline when test administration changes across study waves? Harmonizing cognitive scores across waves in the China Health and Retirement Longitudinal Study [0.03%]
如何评估测试实施变化时的认知衰退？在中国健康与退休追踪研究中协调各波段的认知分数
Yingyan Wu,Yuan S Zhang,Lindsay C Kobayashi et al.
Yingyan Wu et al.
Background: Conducting longitudinal cognitive analyses is an essential part of understanding the underlying mechanism of Alzheimer's disease, especially for social and health behavior determinants. However, the cognitive ...
Deep brain stimulation of the nucleus basalis of Meynert in severe Alzheimer's disease [0.03%]
梅纳尔基底核脑深部刺激治疗严重阿尔茨海默病
Junpeng Xu,Bin Liu,Guosong Shang et al.
Junpeng Xu et al.
Background: Alzheimer's disease (AD) is increasingly prevalent, leading to severe cognitive decline and a diminished quality of life for patients. Nucleus basalis of Meynert deep brain stimulation (NBM-DBS) is a potential...
Blood RNA transcripts show changes in inflammation and lipid metabolism in Alzheimer's disease and mitochondrial function in mild cognitive impairment [0.03%]
血液RNA转录本显示阿尔茨海默病的炎症和脂质代谢变化以及轻度认知障碍中的线粒体功能变化
Jun-Ichi Iga,Yuta Yoshino,Tomoki Ozaki et al.
Jun-Ichi Iga et al.
Background: Abnormal immunity in the periphery has been reported in the pathogenesis of Alzheimer's disease (AD). Objective: In this st...
The association between activities and cognitive health: Stratified analysis by APOE ε4 status [0.03%]
活动与认知健康之间的关联：按APOE ε4状态分层分析
Yeonjung Jane Lee,Ernest Gonzales,Yanyan Wu et al.
Yeonjung Jane Lee et al.
Background: Despite the growing evidence on the modifiable and genetic factors associated with cognitive health, little is known about the role of the apolipoprotein E (APOE) gene ε4 allele in the associations between pr...
The effect of probiotics on select cognitive domains in mild cognitive impairment and Alzheimer's disease: A systematic review and meta-analysis [0.03%]
益生菌对轻度认知障碍和阿尔茨海默病的选择性认知领域的影响：系统评价和荟萃分析
Shashank Tripathi,Meenakshi Kaushik,Rekha Dwivedi et al.
Shashank Tripathi et al.
Background: Mild cognitive impairment (MCI) and Alzheimer's disease (AD) are progressive neurodegenerative disorders, and probiotics may offer therapeutic benefits by modulating gut microbiota and reducing inflammation. ...
Investigation of the effect of green walking and intelligence games on the cognitive skills of individuals between the ages of 50-70 survived COVID-19 disease: A randomized controlled study [0.03%]
绿色行走和智力游戏对50-70岁COVID-19幸存者认知技能的影响的研究：一项随机对照研究
Zahide Akeren,Sevilay Hintistan
Zahide Akeren
Background: Mild cognitive impairment can be considered as the preclinical stage of Alzheimer's disease. With the addition of COVID-19 disease to the cognitive decline that occurs with aging, it may cause dementia with se...