Associations of oxidative balance score and cognition in US older adults: A cross-sectional study of National Health and Nutrition Examination Survey (NHANES) 2011 to 2014 [0.03%]
氧化平衡评分与美国老年人认知能力的关系：2011到2014年国家健康与营养检查调查的横断面研究
Yue Jin,Huajian Lin,Zegen Ye et al.
Yue Jin et al.
Background: Oxidative stress is linked to cognitive decline in the elderly. Diet, as a key energy source, affects brain function and serves as a modifiable risk factor for cognitive decline. ...
Impact of intermediate home-based care on functional health of older adults with stroke in low-income and middle-income countries: A systematic review [0.03%]
中低收入国家卒中老年人家庭基础护理对功能健康影响的系统评价
Temitope Hannah Farombi,Hafiz Ta Khan,Muili Lawal et al.
Temitope Hannah Farombi et al.
Background: Intermediate care services are designed to facilitate transition from medical dependence to functional independence, ultimately improving the overall quality of life. Despite the recognized benefits of intermediate care in rehab...
Sex-specific effects of dietary salt intake on circulating Alzheimer's disease-related biomarkers in aged rats [0.03%]
膳食盐摄入对老年大鼠循环阿尔茨海默病相关生物标志物的性别特异性影响
Fen Sun,Qiu-Xiang Wang,Lu-Ping Zhao et al.
Fen Sun et al.
This study collected plasma samples from aged male and female Sprague Dawley rats (22-24 months old) with varying long-term dietary salt intake (low, 0.1% NaCl; normal, 0.4% NaCl; or clinically relevant high salt, 1% NaCl; for twelve weeks)...
Neuropsychological and clinical indicators of Lewy body and Alzheimer's pathology [0.03%]
路易体与阿尔茨海默病病理学的神经心理及临床指标
Austin J Simpson,Kathryn A Wyman-Chick,Michael S Daniel
Austin J Simpson
Background: Clinical distinction between Alzheimer's disease (AD) and dementia with Lewy bodies (DLB) poses significant challenges due to pathological comorbidity. Similar ages of onset and overlapping cognitive and psych...
Repurposing peripheral immunocytes of Bacillus Calmette Guerin-vaccinated melanoma patients to reveal preventive Alzheimer's disease mechanisms, possibly via the unfolded protein response [0.03%]
通过重新利用卡介苗疫苗接种的黑色素瘤患者的外周免疫细胞来揭示可能预防阿尔茨海默病的机制，可能是通过未折叠蛋白反应实现的
Benjamin Y Klein,Inna Ben-David,Ofer N Gofrit et al.
Benjamin Y Klein et al.
Background: Alzheimer's disease (AD) dysfunctional unfolded protein response (UPR) is revealed by amyloid-β aggregates. Normally, UPR reacts to endoplasmic reticulum stress by resolving misfolded/aggregated proteins, and...
Heterogeneous treatment effects of BCG vaccine on Alzheimer's disease risk [0.03%]
卡介苗对阿尔茨海默病风险的异质性治疗效果
Irfan Chaudhuri,Sudeshna Das
Irfan Chaudhuri
Background: This project has investigated the role of the Bacillus Calmette-Guérin (BCG) vaccine as a potential treatment against Alzheimer's disease (AD) and related dementias (ADRD). ...
Novel donepezil-tacrine hybrid (TAHB3) induces neurodifferentiation, neuroprotective effects, and activates the PI3K/AKT pathway on PC12 cells [0.03%]
新型的-donepezil-tacrine杂合体(TAHB3)诱导神经分化，产生神经营养作用，并激活PC12细胞中的PI3K/AKT通路
Renata Melo Dos Santos Ono,Natália Chermont Dos Santos Moreira,Ivone Carvalho et al.
Renata Melo Dos Santos Ono et al.
Background: Alzheimer's disease (AD) is a neurodegenerative disease characterized by the impairment of cognitive functions and neuronal loss. AD has no cure; current treatments like acetylcholinesterase inhibitors (AChEI)...
Etiologies of rapidly progressive dementias: A systematic review and meta-analysis of causes in worldwide and Latin America [0.03%]
快速进展性痴呆的病因分析：全球及拉丁美洲病因系统回顾与荟萃分析
Jonathan Fernando Cubas Guillen,Carolina Agata Ardohain Cristalli,Waleska Berrios et al.
Jonathan Fernando Cubas Guillen et al.
Background: Rapidly progressive dementia (RPD) is a group of neurological diseases, where three etiologies are particularly relevant: neurodegenerative, prion and autoimmune encephalitis (AIE) diseases. ...
Alzheimer's disease (AD) in multiple sclerosis (MS): A systematic review of published cases, mechanistic links between AD and MS, and possible clinical evaluation of AD in MS [0.03%]
多发性硬化中阿尔茨海默病（AD）的系统回顾：已报道病例，AD和MS之间的机制联系以及MS中可能的临床评估
Ross Cottrill,Anupa Ekanayake,Cooper Grove et al.
Ross Cottrill et al.
Background: Alzheimer's disease (AD) and multiple sclerosis (MS) are two neurological disorders that can pose enormous burden to a person's quality of life. Due to new therapeutic advancements that significantly extend the lifespan, there m...
Machine learning uncovers novel sex-specific dementia biomarkers linked to autism and eye diseases [0.03%]
机器学习揭示了与自闭症和眼病相关的新型性别特异性痴呆生物标志物
Ayub Khan,Ali R Ghasemi,Krista K Ingram et al.
Ayub Khan et al.
Background: Recently, microRNAs (miRNAs) have attracted significant interest as predictive biomarkers for various types of dementia, including Alzheimer's disease (AD), vascular dementia (VaD), dementia with Lewy bodies (...