Comparison between treatment-placebo difference and saved time measures to assess treatment effect in Alzheimer's disease [0.03%]
用于评估阿尔茨海默病治疗效果的疗效差异法和节约时间法的比较研究
Guogen Shan,Yahui Zhang,Guoqiao Wang
Guogen Shan
Background: The estimated treatment-placebo difference from fitted statistical models is often used to evaluate the treatment effect. In addition, we may use time saving as an alternative measure to assess the treatment b...
Studies on curcumin-glucoside in the prevention of alpha-synuclein aggregation [0.03%]
姜黄素糖苷通过调节α-突触核蛋白多态性抑制其聚集的研究
Lakshmi Sowmya Emani,Jayanth K Rao,Jagadeesha Kumar Dasappa et al.
Lakshmi Sowmya Emani et al.
Background: α-synuclein (α-syn) deposition in the mid-brain region is one of the hallmark pathologies of Parkinson's disease (PD). The key steps involve the transformation of α-synuclein into a toxic oligomer and insol...
Exploring the physiotherapy and exercise needs and preferences of nursing home residents with dementia: A qualitative study [0.03%]
探索护理机构中痴呆症患者的物理治疗和运动需求与偏好：一项定性研究
Dennis Boer,Romée Nibbering,Charlotte Schmidt et al.
Dennis Boer et al.
Background: Exercise is widely employed to prevent functional decline in individuals with Alzheimer's disease and other forms of dementia. Exercise interventions are often supervised by physiotherapists, particularly in W...
Audio review as a measure of quality assurance and control of cognitive assessments in Alzheimer's disease studies: An experience from Japanese Trial-Ready Cohort Study [0.03%]
听觉审查作为阿尔茨海默病研究中认知评估质量保证和控制的措施：日本试验就绪队列研究的经验报告
Kenichiro Sato,Ryoko Ihara,Yoshiki Niimi et al.
Kenichiro Sato et al.
Background: Clinical trials targeting preclinical Alzheimer's disease (AD) require accurate cognitive assessments to detect subtle changes over time. Audio review of assessment sessions has been proposed as a quality assu...
Late onset epilepsy and dementia with Lewy bodies: Underestimated association? [0.03%]
晚年发病的癫痫和路易体痴呆：被低估的关联吗？
Maximilien Porché,Julien Dumurgier,Claire Hourrègue et al.
Maximilien Porché et al.
Relationship between Alzheimer's disease (AD) and late onset epilepsy (LOE) has been widely described leading to an expansion of the clinical spectrum of AD. Dementia with Lewy bodies (DLB) has scarce data detailing its association with epi...
Dual impact of neuroinflammation on cognitive and motor impairments in Alzheimer's disease [0.03%]
神经炎症对阿尔茨海默病认知障碍和运动功能损害的双重影响
Sodiq Fakorede,Olubodun M Lateef,Wilson Amemewon Garuba et al.
Sodiq Fakorede et al.
Neuroinflammation plays a crucial role in the progression of Alzheimer's disease (AD), contributing to both cognitive decline and motor impairment. This review examines the dual impact of neuroinflammatory processes, particularly the activa...
A comparison of electronic and paper versions of the Quick Mild Cognitive Impairment (Q mci-CN) screen [0.03%]
简体中文标题：电子版和纸质版快速轻度认知障碍(Q MCI-CN)筛查的比较研究
Yangfan Xu,Jiadan Yu,Xiaocong Mo et al.
Yangfan Xu et al.
Background: There is a growing focus on digitalizing screening instruments for use on computerized, mobile devices. However, few studies have compared the performance of electronic and traditional 'pen and paper' formats....
Association between social connectedness and mild cognitive impairment: A case-control study in aging rural Indians [0.03%]
社会交往与轻度认知障碍的关联——一项关于印度农村老年人的病例对照研究
Pooja Rai,Jonas S Sundarakumar
Pooja Rai
There is a scarcity of evidence on the association between social connectedness and cognitive impairment in the rural Indian population. This cross-sectional study included rural Indians aged 45+ years (n = 5805) from an ongoing aging cohor...
Perioperative care and recovery outcome of deep jugular venous lymphatic anastomosis in Alzheimer's disease: A case report [0.03%]
阿尔茨海默病深颈静脉淋巴管吻合术的围手术期护理及恢复效果观察：1例报告
Li Chen,Lang Peng,Xiaojing Guo et al.
Li Chen et al.
This case reports a 74-year-old female from eastern China presented with memory loss, dyscalculia, language disorders, diagnosed with Alzheimer's disease and underwent deep cervical venous lymphatic anastomosis. After rigorous preoperative ...
Efficacy and safety of focused ultrasound-mediated blood-brain barrier opening in Alzheimer's disease: A systematic review and meta-analysis [0.03%]
聚焦超声介导的血脑屏障开放在阿尔茨海默病中有效性和安全性的系统评价和meta分析
Mengru Bai,Hanlei Lyv,Xin Zhou et al.
Mengru Bai et al.
Background: Alzheimer's disease (AD) manifests as an insidiously progressive neurodegenerative pathology, wherein the current therapeutic armamentarium remains constrained to symptomatic management, highlighting an urgent...