Association between SLC2A9 Genetic Variants and Risk of Hyperuricemia in a Uygur Population [0.03%]
SLC2A9基因多态性与维吾尔人群高尿酸血症的相关性研究
Yu-Ping Sun,Fei-Li Xu,Dan-Dan Yan et al.
Yu-Ping Sun et al.
EN: Summary]This study aimed to test the effects of five single nucleotide polymorphisms within SLC2A9 on uric acid level in a special ethnic population, the Uygurs in Xinjiang, China. According to our inclusion and exclusion criteria, Uygu...
Efficacy of Long-term Selenium Supplementation in the Treatment of Chronic Keshan Disease with Congestive Heart Failure [0.03%]
长期补硒治疗慢性克山病心力衰竭的疗效观察
Yan-He Zhu,Xin-Feng Wang,Guang Yang et al.
Yan-He Zhu et al.
Few effective treatments for chronic Keshan disease have been available till now. The efficacy of long-term selenium supplementation in the treatment of chronic Keshan disease with congestive heart failure is inconclusive. This study aimed ...
HDAC-selective Inhibitor Cay10603 Has Single Anti-tumour Effect in Burkitt's Lymphoma Cells by Impeding the Cell Cycle [0.03%]
组蛋白去乙酰化酶选择性抑制剂Cay10603通过阻碍细胞周期进程对Burkitt淋巴瘤细胞有单药抗肿瘤作用
Xiu-Juan Ma,Gang Xu,Zhi-Jie Li et al.
Xiu-Juan Ma et al.
Histone deacetylases (HDACs) inhibitors are novel in cancer therapy nowadays. HDAC6-selective inhibitors exert advantageous effects due to higher selectivity and less toxicity. We explored the anti-tumor effect and the molecular mechanism o...
Prognostic Value of D-Dimer in Patients with Diffuse Large B-cell Lymphoma: A Retrospective Study [0.03%]
D-二聚体在弥漫大B细胞淋巴瘤患者中的预后价值：回顾性研究
Yu-di Geng,Yi-Ren Chen,Jin Jin et al.
Yu-di Geng et al.
This study evaluated the significance of serum D-Dimer for predicting survival of patients with diffuse large B-cell lymphoma (DLBCL). We analyzed the clinical data from 113 patients who were newly diagnosed with DLBCL at Tongji Hospital fr...
Early Detection of Myelodysplastic Syndrome/Leukemia-associated Mutations Using NGS Is Critical in Treating Aplastic Anemia [0.03%]
aplasia患者中早期检测髓系恶性肿瘤相关基因突变的重要性和时机-一项基于NGS的研究
Xiang Li,Yao-Hui Wu,Si-Si Cai et al.
Xiang Li et al.
Distinguishing between aplastic anemia (AA) and hypoblastic myelodysplastic syndrome (hMDS) with a low percentage of bone marrow (BM) blasts (
Monitoring and Analysis of Chinese Chronic Myeloid Leukemia Patients Who Have Stopped Tyrosine Kinase Inhibitor Therapy [0.03%]
中国慢性髓性白血病患者停用酪氨酸激酶抑制剂后的监测和分析
Na Shen,Yong You,Zhao-Dong Zhong et al.
Na Shen et al.
Discontinuation of tyrosine kinase inhibitor (TKI) therapy after achieving a persistent deep molecular response (DMR) is an urgently needed treatment goal for chronic myeloid leukemia (CML) patients and has been included in the National Com...
Increased Risk of Chronic Kidney Diseases in Patients with Metabolic Syndrome: A 3-year Prospective Cohort Study [0.03%]
代谢综合征患者慢性肾脏病发病风险增加：一项3年前瞻性队列研究
Ying Hu,Li-Xin Shi,Qiao Zhang et al.
Ying Hu et al.
The relationship of metabolic syndrome (MS) and its components with incident chronic kidney disease (CKD) and rapid decline of estimated glomerular filtration rate (eGFR) was investigated. A total of 10 140 patients participating in the epi...
Notoginseng Saponin Rg1 Prevents Cognitive Impairment through Modulating APP Processing in Aβ1-42-injected Rats [0.03%]
绞股蓝皂苷Rg1通过调节APP的处理过程防止Aβ1-42注射大鼠的认知障碍
Shang-Zhi Liu,Wei Cheng,Jia-Wei Shao et al.
Shang-Zhi Liu et al.
With the intensification of the aging process of the world, Alzheimer's disease (AD), which is the main type of senile dementia, has become a primary problem in the present society. Lots of strategies have been used to prevent and treat AD ...
Jian-Li Wu,Jing Jia,Meng-Zhou He et al.
Jian-Li Wu et al.
Preeclampsia (PE) remains a leading cause of maternal and perinatal morbidity and mortality in obstetrics worldwide. No effective treatments to reduce its incidence and severity in clinical practice are currently available. A variety of hyp...
Serum Biomarkers for Early Diagnosis of Chinese X-CGD Children: Case Reports and a Literature Review [0.03%]
儿童X-CGD早期诊断血清生物标志物的病例报道与文献复习
Ling Hou,Wan-Ting Niu,Hong-Yan Ji et al.
Ling Hou et al.
Since X-linked chronic granulomatosis disease (X-CGD) exhibits no specific clinical symptoms at an early stage, early diagnosis is difficult and depends predominantly on neonatal screening. Therefore, the aim of this study was to explore ro...