Invasiveness, SOX2 Expression, and Resection Outcomes in TF-Defined PitNETs After Extra-Pseudocapsular Resection [0.03%]
扩大囊外切除的视神经胶质瘤（PitNETs）的侵袭性、SOX2表达及TF定义后的切除效果
Xing-Bo Li,Kuo Zeng,Xue-Yan Wan et al.
Xing-Bo Li et al.
Objective: To evaluate the associations between transcription factor (TF)-defined molecular lineages and the clinical characteristics of pituitary neuroendocrine tumors (PitNETs). ...
Automatic Classification of Anterior Talofibular Ligament Based on 2D Convolutional Neural Network [0.03%]
基于二维卷积神经网络的距腓前韧带自动分类
Feng Li,Xiao-Shan Wang,Ting Li et al.
Feng Li et al.
Objective: To investigate the feasibility of 2D convolutional neural networks (CNNs) in the automatic classification of anterior talofibular ligaments (ATFLs) on MR images. ...
Hong-Yu Chen,Na Li,Xiao-Dan Zhu et al.
Hong-Yu Chen et al.
Endometriosis (EM) is a chronic, estrogen-dependent inflammatory disease affecting approximately 10% of women of reproductive age worldwide, causing debilitating pelvic pain, infertility, and substantially impaired quality of life. Conventi...
A 3D PDMS Scaffold Microchip Platform for Non-Invasive Detection of Circulating Endometrial Cells: Revolutionizing Endometriosis Diagnosis [0.03%]
一种用于非侵入性检测循环子宫内膜细胞的3D PDMS支架微芯片平台：重塑子宫内膜异位症诊断方法
Shu-Hao Yang,Yi-Ke Wang,Li-Li Xu et al.
Shu-Hao Yang et al.
Objective: To address the urgent need for non-invasive diagnosis of endometriosis, this study developed a novel microfluidic platform utilizing a three-dimensional (3D) polydimethylsiloxane scaffold microchip to efficient...
KLF4 in Parkinson's Disease: Decoding the Molecular Puzzle of Neuroinflammation, Oxidative Stress, and Emerging Therapies [0.03%]
帕金森病中的KLF4：解码神经炎症、氧化应激及新兴疗法的分子 puzzle
Anjali Kumari,Khadga Raj Aran
Anjali Kumari
Parkinson's disease (PD) is the most prevalent neurodegenerative movement condition. Tremors, stiffness, bradykinesia/akinesia, and postural instability are its primary motor symptoms; nevertheless, the clinical features also include non-mo...
Peptide Loading Complex in Cancer: From Peptide Translocation, Editing, and Loading into MHC-I to a Potential Therapeutic Target [0.03%]
肿瘤中MHCI类分子肽加载复合体从肽转运、编辑和装入到潜在治疗靶点
Omer Qutaiba B Allela,Abdulkareem Shareef,Hayder Naji Sameer et al.
Omer Qutaiba B Allela et al.
The peptide-loading complex (PLC) is a pivotal endoplasmic reticulum (ER) protein machinery that facilitates peptide translocation, editing, and loading onto major histocompatibility complex class I (MHC-I) to allow recognition of infected ...
Pain Medicine Specialist: Championing High-Quality Development for Neuromodulation Technology [0.03%]
疼痛管理专家：推动神经调控技术高质量发展
Ming Chen,Yang-Jia Shi,Kun Chen et al.
Ming Chen et al.
Neuromodulation technology, an interdisciplinary field integrating neuroscience, engineering, and clinical medicine, offers novel therapeutic paradigms for numerous intractable diseases. In pain medicine, it modulates nervous system functio...
Matrix Competence Failure in Osteoporosis: Mechanosensing, Osteoimmune Crosstalk, and Fragility Beyond Bone Mineral Density [0.03%]
骨质疏松症中的矩阵能力缺陷：力学感受、骨免疫互作及骨矿物质密度之外的骨折风险因素
Tian-Ge Xia,Yi-Jie Zhang,Shao-Shuo Li et al.
Tian-Ge Xia et al.
Osteoporosis is typically characterized by reduced bone mass and deterioration of microarchitecture. However, bone mineral density (BMD) does not fully account for the wide variations in skeletal fragility. In this study, we propose that ma...
Perioperative Esmolol Is Associated with Early Opioid Sparing in Patients with Ischemic Heart Disease: Evidence from a Retrospective Cohort and an Incisional Pain Rat Model [0.03%]
围术期艾司洛尔可早期减少缺血性心脏病患者阿片类药物使用：来自回顾性队列和切口痛大鼠模型的证据
Yue-Yang Xin,Ning Yang,Hao Chen et al.
Yue-Yang Xin et al.
Objective: Previous studies have confirmed the opioid-sparing and analgesic properties of perioperative esmolol, yet relevant clinical evidence specifically focusing on patients with ischemic heart disease (IHD) remains s...
Electroacupuncture as Adjunctive Therapy for Organ Dysfunction Among Chinese ICU Patients with Sepsis: Study Protocol for a Randomized Clinical Trial [0.03%]
电针作为中国重症监护室中感染性脓毒症器官功能障碍患者的辅助治疗：随机对照临床试验方案
Qi Meng,Ling-Ling Yu,Xiang-Hong Jing et al.
Qi Meng et al.
Background: Sepsis is a dysregulated response of the host to infection that can lead to life-threatening organ dysfunction and remains a leading cause of mortality. Early recovery of impaired organ function is crucial for...