Lei Lei,Zhi-Ming Jiang,Cheng-Hui Li et al.
Lei Lei et al.
Small cell lung cancer (SCLC) is recognized as one of the most aggressive and fatal malignant tumors. No significant improvement has been made to prolong the survival of SCLC patients. This study aimed to examine the mutation status of K-Ra...
Probiotic Mixture VSL#3 Alleviates Dextran Sulfate Sodium-induced Colitis in Mice by Downregulating T Follicular Helper Cells [0.03%]
益生菌混合物VSL#3通过下调滤泡辅助性T细胞缓解小鼠结肠炎
Xiao-Jing Liu,Ran Yu,Kai-Fang Zou
Xiao-Jing Liu
Clinical trials have shown beneficial effects of probiotics on inflammatory bowel diseases (IBD), although the exact mechanism remains unknown. VSL#3, a mixture of 8 probiotic bacteria, has been confirmed to have adjunctive therapeutic effe...
Lipopolysaccharide Inhibits FI-RSV Vaccine-enhanced Inflammation Through Regulating Th Responses [0.03%]
脂多糖通过调控Th细胞反应抑制FI-RSV疫苗增强的炎症反应
Wei Yin,Hong-Yong Li,Bo-Yang Zheng et al.
Wei Yin et al.
Respiratory syncytial virus (RSV) infection is the primary cause of respiratory disease in infants. The formalin-inactivated RSV (FI-RSV) vaccine resulted in an enhanced respiratory disease (ERD) in infants upon natural RSV infection, which...
Inhibition of PARP1 Increases IRF-dependent Gene Transcription in Jurkat Cells [0.03%]
抑制PARP1可增加Jurkat细胞中的IRF依赖性基因转录
Cheng Wang,Meng Du,Dan Huang et al.
Cheng Wang et al.
Poly(ADP-ribose) polymerase 1 (PARP1) plays important roles in the regulation of transcription factors. Mounting evidence has shown that inhibition of PARP1 influences the expression of genes associated with inflammatory response. Interfero...
Chao Wang,Chen Yang,Yu-Chen Chen et al.
Chao Wang et al.
Peptides play crucial roles in various physiological and pathological processes. Consequently, the investigation of peptide-based drugs is a highlight in the research and development of new drugs. However, natural peptides are not always id...
The Role of RP105 in Cardiovascular Disease through Regulating TLR4 and PI3K Signaling Pathways [0.03%]
RP105通过调节TLR4和PI3K信号通路在心血管疾病中的作用研究
Jian Yang,Ping Zeng,Jun Yang et al.
Jian Yang et al.
Raidoprotective 105 (RP105) was first discovered on the surface of mouse B cells and it has been demonstrated that RP105 can function as an inflammatory regulator in cardiovascular disease (CVD), such as myocardial ischemic reperfusion inju...
Absorption Characteristics of Novel Compound Calcium Carbonate Granules: Effects of Gastric Acid Deficiency and Exogenous Weak Acids [0.03%]
新型复方碳酸钙颗粒剂的吸收特性：胃酸缺乏及外源弱酸对其影响
Hong-Dan Chen,Yi-Ping Chen,Rui Xie et al.
Hong-Dan Chen et al.
Calcium carbonates are commonly administered as supplements for conditions of calcium deficiency. We report here pharmacokinetic characteristics of a novel formulation, calcium carbonate compound granules (CCCGs), forming complexes of calci...
Optimal Cut-off Point of Waist to Height Ratio in Beijing and Its Association with Clusters of Metabolic Risk Factors [0.03%]
腰高比的北京适宜切点及其与代谢异常组合的关系
Jing Dong,Si-Si Wang,Xi Chu et al.
Jing Dong et al.
A host of studies found waist-to-height ratio (WHtR) having higher diagnostic value than other abdominal obesity anthropometric indicators for metabolic disorders. But the cut-off points are still not consistent. This study was aimed to exp...
Adverse Respiratory Events Increase Post-anesthesia Care Unit Stay in China: A 2-year Retrospective Matched Cohort Study [0.03%]
中国术后恢复室滞留的不良呼吸事件增加：一项两年回顾性队列研究
Shang-Kun Liu,Gang Chen,Bi Yan et al.
Shang-Kun Liu et al.
Despite growing attention to patients' safety worldwide, no data were available on the impact of adverse respiratory events (AREs) on post-anesthesia care and post-operation care in China. This study evaluated the occurrence of AREs, the im...
Observational Study
Current medical science. 2019 Apr;39(2):325-329. DOI:10.1007/s11596-019-2038-y 2019
Longitudinal Quantitation of Tooth Displacement in Chinese Adolescents with Normal Occlusion [0.03%]
正常咬合的中国青少年牙齿纵向位移量化分析
Jie-Ni Zhang,Xue-Dong Wang,Jiu-Xiang Lin
Jie-Ni Zhang
This longitudinal study aims to analyze the different modes of the maxillary and mandibular tooth displacement in subjects, who were aged 12.5-17.5 years (150-210 months), with untreated normal (Class I) occlusion. Longitudinal lateral ceph...