Electroacupuncture Improves Gastrointestinal Motility in Rats with Functional Dyspepsia via the GDNF/GFRα1/PI3K/Akt Signaling Pathway [0.03%]
电针通过神经营养因子(GDNF)/GFRα1/PI3K/Akt信号通路改善功能性消化不良模型大鼠胃肠动力功能研究
Li Zhou,Xiao-Li Pan,De-Qian Yang et al.
Li Zhou et al.
Objective: Abnormal gastrointestinal motility plays a crucial role in the pathogenesis of functional dyspepsia (FD). Although electroacupuncture (EA) has demonstrated efficacy in FD treatment, its precise mechanism remain...
Artificial Intelligence in Traditional Chinese Medicine: Multimodal Fusion and Machine Learning for Enhanced Diagnosis and Treatment Efficacy [0.03%]
人工智能在中医中的应用：多模态融合和机器学习在中医诊断及治疗中的有效性研究
Jie Wang,Yong-Mei Liu,Jun Li et al.
Jie Wang et al.
Artificial intelligence (AI) serves as a key technology in global industrial transformation and technological restructuring and as the core driver of the fourth industrial revolution. Currently, deep learning techniques, such as convolution...
Yinchenhao Decoction Combined with Praziquantel Ameliorates Inflammation and Hepatic Fibrosis in Schistosoma japonicum-Infected Mice [0.03%]
茵陈蒿汤联合吡喹酮改善日本血吸虫感染小鼠的炎症和肝纤维化
Jia-Hua Liu,Mei Peng,Fang Chen et al.
Jia-Hua Liu et al.
Objective: This study aimed to investigate the therapeutic effects and underlying mechanisms of the combination of Yinchenhao decoction (YCHD) and praziquantel (PZQ) in a Schistosoma japonicum (S. japonicum)-induced mouse...
Physiological Reconstruction for Moderate-Severe Pelvic Organ Prolapse: A Multicenter Retrospective Self-Controlled Study [0.03%]
中重度盆腔器官脱垂生理重建的多中心回顾性自身对照研究
Zhen-Hua Gao,Xing-Qi Wang,Kun-Bin Ke et al.
Zhen-Hua Gao et al.
Objective: This is a self-controlled multicenter retrospective study based on the clinical efficacy and complications of physiological reconstruction in the treatment of moderate and severe pelvic organ prolapse. ...
Chop Deficiency Exacerbates Cyclophosphamide-Induced Overactive Bladder via Impaired Macrophage Apoptosis [0.03%]
缺氧诱导因子不足通过损害巨噬细胞凋亡加重环磷酰胺引起的过度活动膀胱症状
Ya-Nan Wang,Xiang-Dong Guo,Chun-Yu Zhang et al.
Ya-Nan Wang et al.
Objective: Overactive bladder, a storage syndrome characterized by urinary urgency, frequency, and nocturia with or without urgency urinary incontinence, severely affects the quality of life of patients. The aim of this s...
Anatomic Variations of the Lacrimal Sac Relative to Middle Turbinate Axilla and Skull Base in Chinese Patients with Nasolacrimal Duct Obstruction: A CT-Dacryocystography [0.03%]
中国鼻泪管阻塞患者泪囊解剖变异的CT- dacryo造影研究
Hui-Yang Ai,Xu-Hui Chen,Qi-Lan Hu et al.
Hui-Yang Ai et al.
Objective: The middle turbinate axilla (MTA) is a crucial anatomical landmark for localizing the lacrimal sac (LS) during endonasal dacryocystorhinostomy (En-DCR). Despite being a standard surgical procedure, En-DCR may l...
Circulating T Regulatory Cells Are Persistently Reduced in Non-Severe Acquired Aplastic Anemia [0.03%]
非重症获得性再生障碍性贫血患者的循环T调节细胞水平持续降低
Pasqualina Scala,Valentina Giudice,Denise Morini et al.
Pasqualina Scala et al.
Objective: Acquired aplastic anemia (aAA) is characterized by an autologous immunological attack against hematopoietic stem and progenitor cells, and immunotolerance disruption is frequent, with reduced T regulatory cells...
Clinical and Genetic Characteristics of Patients with Early-Onset Diabetes Involving at Least Two Consecutive Generations: Whole-Exome Sequencing in Probands from 25 Pedigrees [0.03%]
早发糖尿病连续两代以上家系的临床及遗传特征分析：25个家系先证者的外显子组测序研究
Chun-Qiong Ran,Ying Su,Xiong Wang et al.
Chun-Qiong Ran et al.
Background: The molecular mechanisms of early-onset multigenerational diabetes remain unknown. This study aimed to investigate the clinical and genetic characteristics of early-onset diabetes involving at least two consec...
Inflammation-Related Factors S100A9 and TLR2 in Cardiomyocyte Hypertrophy [0.03%]
心肌细胞肥厚相关炎症因子S100A9和TLR2的研究
Ke-Jia Jin,Le Pan,Chen-Xing Huang et al.
Ke-Jia Jin et al.
Objective: The pathogenesis and progression of heart failure (HF) are governed by complex, interconnected biological pathways, with dysregulated immune responses and maladaptive cardiac remodeling playing central roles. A...
Identification of Immune-Related Ferroptosis Biomarkers in Diabetic Kidney Disease and Screening of Associated Inhibitors [0.03%]
糖尿病肾病中铁死亡相关生物标志物的鉴定及其潜在抑制剂的筛选
Nan-Nan Zhang,Yi Zhu,Qiu-Yan Huang et al.
Nan-Nan Zhang et al.
Objective: Immune infiltration and ferroptosis play pivotal roles in the progression of diabetic kidney disease (DKD). However, investigations of immune cell-related ferroptosis genes (ICRFGs) in the context of DKD are in...