Targeting Calprotectin S100A8/A9 to Overcome AML Progression in DNMT3A-Mutant Cells [0.03%]
靶向CALPROTECTIN S100A8/A9以克服DNMT3A突变型急性髓系白血病细胞的进展
Xiao-Ya Cai,Gui-Qin Huang,Ye-Ming Zhou et al.
Xiao-Ya Cai et al.
Objective: To investigate the effects of calprotectin (S100A8/A9) on the biological activity of acute myeloid leukemia (AML) cells harboring a DNA methyltransferase 3A (DNMT3A) mutation and to explore the underlying molec...
Risk Factors for Lymph Node Metastasis in Stage pT1 Invasive Lung Adenocarcinoma [0.03%]
早期肺腺癌淋巴结转移的危险因素分析
Shou-Kang Li,Nai-Cheng Song,Quan Liu et al.
Shou-Kang Li et al.
Objective: To analyze the risk factors for lymph node metastasis (LNM) in patients with stage pT1 lung adenocarcinoma to select a more appropriate surgical option. ...
Aberrant Sialylation in Ovarian Cancer: Orchestrating Progression, Metastasis, and Therapeutic Hurdles [0.03%]
卵巢癌中唾液酸糖链组装的异常及其在肿瘤进展、转移和治疗中的作用机制探究
Yu-Xin Chen,Guang-Nian Zhao,Qing-Lei Gao
Yu-Xin Chen
Ovarian cancer (OC), a highly lethal gynaecological malignancy, is often diagnosed at advanced stages, resulting in a poor prognosis. Sialylation, an important form of glycosylation, significantly contributes to the progression of various s...
The Prognostic Value of the Systemic Immune-Inflammation Index in Glioblastoma Patients and the Establishment of a Nomogram [0.03%]
系统免疫炎症指数在胶质母细胞瘤患者中的预后价值及 nomogram 的建立
Hao Xu,Li-Hao Jiang,Sheng-Nan Yu et al.
Hao Xu et al.
Objective: The systemic immune-inflammation index (SII) has recently attracted significant interest as a new biomarker for predicting the prognosis of patients with glioblastoma (GBM). However, the predictive significance...
A Simple Modification Results in a Significant Improvement in Measuring the Size of Extracellular Vesicles [0.03%]
对测量外泌体大小的方法进行改进显著成效
Xiao-Jun Liu,Zhen-Sheng Ma,Yan Li et al.
Xiao-Jun Liu et al.
Objective: Size distribution is an important biophysical property of extracellular vesicles (EVs). EVs include small EVs (s-EVs) and large EVs (l-EVs) by size. Differential ultracentrifugation (dUC) is widely used to sepa...
Durational Exposure to Particulate Matter and Changes in Fertility Intentions: A Study of Adults in China [0.03%]
暴露于颗粒物与生育意愿变化的关系——对中国成年人的研究
Jia-Yu Wang,Xin Yun,Rui Qu et al.
Jia-Yu Wang et al.
Objective: The effects of prolonged exposure to persistently elevated atmospheric pollutants, commonly termed air pollution waves, on fertility intentions remain inadequately understood. This study aims to investigate the...
Comparative Efficacy of Retrograde Pubic Ramus Intramedullary Nails and Percutaneous Cannulated Screws in Treating Anterior Pelvic Ring Fractures: A Retrospective Cohort Study [0.03%]
股骨逆行经粗隆髓内钉与皮质骨轨迹螺钉治疗前环骨盆骨折的疗效比较：回顾性队列研究
En-Zhi Yin,Xue-Feng Yuan,Yang-Xing Luo et al.
En-Zhi Yin et al.
Objective: To compare the clinical outcomes of retrograde pubic ramus intramedullary nail (RPRIN) and percutaneous cannulated screw (PCS) in the treatment of anterior pelvic ring fractures (APRFs). ...
Causal Links Between Gut Microbiota and Vitamin Deficiencies: Evidence from Mendelian Randomization Analysis [0.03%]
基于孟德尔随机化分析的技术肠道菌群与维生素缺乏的因果关系证据研究
Zi-Xuan Hou,Wen-Jing Li,Rong Pi et al.
Zi-Xuan Hou et al.
Objective: Vitamin deficiencies, particularly in vitamins A, B12, and D, are prevalent across populations and contribute significantly to a range of health issues. While these deficiencies are well documented, the underly...
Jin Zhang,Xiang Peng,Man Li et al.
Jin Zhang et al.
Depression is a multifaceted disorder with a largely unresolved etiology influenced by a complex interplay of pathogenic factors. Despite decades of research, it remains a major condition that significantly diminishes patients' quality of l...
Pathogen Detection in Spinal Infections: Next-Generation Sequencing Versus Conventional Microbiological Methods [0.03%]
脊柱感染病原体检测：下一代测序与传统微生物方法
Khan Akhtar Ali,Ling-Xiao He,Fang Gao et al.
Khan Akhtar Ali et al.
Objective and background: Early and accurate diagnosis of spinal infections, including spinal tuberculosis, is pivotal for effective treatment but remains challenging. This study aims to assess the diagnostic yield of met...