PMEPA1-Mediated Treg Cell Impairment Promotes Endometrial Stromal Invasion via Excessive PI3K/AKT Signaling in Endometriosis [0.03%]
PMEPA1通过过度活化PI3K/AKT信号促进子宫内膜异位病灶巨噬细胞功能异常及内膜间质侵袭能力增强
Ya-Qin Peng,Lu Wang,Ai-Li Tan et al.
Ya-Qin Peng et al.
Objective: Although immune dysregulation is implicated in the pathogenesis of endometriosis (EMs), the specific role of prostate transmembrane protein androgen induced 1 (PMEPA1) in modulating the function of regulatory T...
A Real-World Pharmacological Assessment of Tenofovir Amibufenamide and Tenofovir Alafenamide in 48-Week Chronic Hepatitis B Treatment: Efficacy, Safety, and Cost-Effectiveness [0.03%]
恩曲他滨/替诺福韦胺贝法南与恩曲他滨/替诺福韦阿德福韦酯治疗慢性乙型肝炎48周的药代动力学研究：疗效，安全性及成本效益分析
Li-Li Liu,Yi Feng,Chao-Yi Ren et al.
Li-Li Liu et al.
Objective: Chronic hepatitis B (CHB), characterized by a significant global disease burden and substantial healthcare costs, remains a critical public health challenge. Although tenofovir amibufenamide (TMF) and tenofovir...
Collagen-Coated 3D-TechTra Scaffold Integrated with Human Umbilical Cord Mesenchymal Stem Cells Enhances Tracheal Tissue Regeneration and Reduces Stenosis in Rabbit Models [0.03%]
人脐带间充质干细胞联合胶原蛋白包被的三维气管支架修复气管缺损的研究
Badrul Hisham Yahaya,Nur Fitriyani Afiqah Abu Bakar,Asmak Abdul Samat et al.
Badrul Hisham Yahaya et al.
Objective: This study aimed to evaluate the potential of a collagen-coated, 3D-printed tracheal scaffold (3D-TechTra) integrated with human umbilical cord mesenchymal stem cells (hUC-MSCs) for tracheal tissue regeneration...
miR-320a Regulates Placenta Endothelial Function After Fetal Cardiopulmonary Bypass via the ATG7-SIRT1/FOXO1 Pathway [0.03%]
miR-320a通过ATG7-SIRT1/FOXO1通路调节胎儿心肺旁路后胎盘内皮功能
Yun Teng,Miao Tian,Xiao-Kang Luo et al.
Yun Teng et al.
Objective: Placental dysfunction induced by fetal cardiopulmonary bypass (CPB) imposes limitations on the clinical application of this procedure. The potential impact of microRNA-mediated autophagy in placental endothelia...
Association of MiR-29b/BRD4 with Airway Dysbiosis in Chronic Obstructive Pulmonary Disease after Smoking Cessation [0.03%]
MiR-29b/BRD4与吸烟者慢性阻塞性肺疾病戒烟后气道菌群失调的关系研究
Si-Yi Zhou,Yu-Xin Zeng,Yu Tao et al.
Si-Yi Zhou et al.
Objective: Our earlier research revealed a connection between microRNA-29b (miR-29b) and bromodomain-containing protein 4 (BRD4) and airway inflammation in chronic obstructive pulmonary disease (COPD). We examined their c...
Therapeutic Effects of Qifangfeixian Granules on Pulmonary Fibrosis in Patients with Interstitial Lung Disease [0.03%]
气防飞仙颗粒治疗间质性肺疾病肺纤维化患者的临床疗效观察
Lu-Qin Yang,Hui-Lan Zhang,Yong-Hao Li
Lu-Qin Yang
Objective: To investigate the curative effect of the Qifangfeixian granule on interstitial lung disease (ILD). Methods: This study comb...
Integrating CT Radiomics and Clinical Information to Predict Prognosis of Advanced NSCLC Patients Receiving Chemoimmunotherapy [0.03%]
结合CT影像组学和临床信息预测晚期NSCLC患者化疗免疫治疗预后
Hao Zhong,Hao-Han Zhang,Jie Wu et al.
Hao Zhong et al.
Objective: This study aimed to develop an effective predictive tool that combines radiomics and clinical information to predict the survival outcomes of patients with advanced non-small cell lung cancer (NSCLC) undergoing...
The Protective Effects of Quercetin on Ferritinophagy in Alcoholic-Induced Liver Iron Overload [0.03%]
槲皮素对酒精诱导的肝铁过载细胞 ferritinophagy 的保护作用
You Jin,Hong-Mei Zeng,Chan Peng et al.
You Jin et al.
Objective: Iron overload resulting from chronic alcohol consumption may aggravate liver damage, and the potential mechanisms involving ferritinophagic flux and the role of naturally occurring quercetin in alcohol-induced ...
Effect of Screw Distribution on Stability and Interfragmentary Strain of Lower Tibial Fractures: A Finite Element Analysis [0.03%]
螺钉分布对下胫骨骨折内固定稳定性及断端应力的影响：有限元分析
Huan Su,Huan Xiao,Jian-Jun Zhou et al.
Huan Su et al.
Objective: The aim of this study was to explore the influence of working length (determined by the screw position) on the stiffness and interfragmentary strain (IFS) of femoral locking compression plate (LCP) external fix...
Global, Regional, and National Burden of Pulmonary Arterial Hypertension from 1990 to 2021 and Projections to 2040: A Systematic Analysis of Incidence, Mortality, and Disability-Adjusted Life Years [0.03%]
1990年～2021年全球、区域和国家肺动脉高压的疾病负担及2040年前预测：系统性分析发病率、死亡率与伤残调整寿命年
Lin-Ling Yu,Ding-Sheng Jiang,Xiong Wang et al.
Lin-Ling Yu et al.
Objective: Pulmonary arterial hypertension (PAH) poses a growing global health challenge, yet comprehensive epidemiological data remain limited. This study aims to assess the burden of PAH from 1990 to 2021 and project tr...