Long-term outcomes of endoscopic submucosal dissection for high-grade dysplasia and early-stage carcinoma in the colorectum [0.03%]
内镜下黏膜下剥离术治疗重度不典型增生和早期结直肠癌的长期疗效分析
Tao Chen,Wen-Zheng Qin,Li-Qing Yao et al.
Tao Chen et al.
Background: Colorectal carcinomas (CRCs) arise from premalignant precursors in an adenoma-carcinoma sequence, in which adenoma with high-grade dysplasia (HGD) and early-stage carcinoma are defined as advanced neoplasia. A...
Decreased macrophage inflammatory protein (MIP)-1α and MIP-1β increase the risk of developing nasopharyngeal carcinoma [0.03%]
巨噬细胞炎性蛋白(MIP)-1α和MIP-1β降低增加患鼻咽癌的风险
Meng-Jie Yang,Jie Guo,Yan-Fang Ye et al.
Meng-Jie Yang et al.
Background: The association of circulating inflammation markers with nasopharyngeal carcinoma (NPC) is still largely unclear. This study aimed to comprehensively explore the relationship between circulating cytokine level...
EYA4 inhibits hepatocellular carcinoma growth and invasion by suppressing NF-κB-dependent RAP1 transactivation [0.03%]
EYA4通过抑制NF-κB依赖的RAP1转激活来抑制肝癌细胞生长和侵袭能力
Shi-Jing Mo,Xun Hou,Xiao-Yi Hao et al.
Shi-Jing Mo et al.
Background: Our previous studies demonstrated that eyes absent homolog 4 (EYA4), a member of the eye development-related EYA family in Drosophila, is frequently methylated and silenced in hepatocellular carcinoma (HCC) sp...
Cancer mortality in Serbia, 1991-2015: an age-period-cohort and joinpoint regression analysis [0.03%]
塞尔维亚1991-2015年癌症死亡率：年龄-时期-队列及joinpoint回归分析
Milena Ilic,Irena Ilic
Milena Ilic
Background: As the result of dramatic political changes, civil wars, and a long-term refugee crisis from the end of the last to beginning of this century, the population of Serbia has experienced significant health proble...
Li Yan,Wei Zhang
Li Yan
Precision medicine just witnessed two breakthroughs in oncology in 2017. Pembrolizumab (Keytruda), Merck's anti-programmed cell death-1 (PD-1) monoclonal antibody (mAb), received accelerated approval in May 2017 by the US Food and Drug Admi...
Nasopharyngeal brushing: a convenient and feasible sampling method for nucleic acid-based nasopharyngeal carcinoma research [0.03%]
鼻咽刷检技术用于核酸型鼻咽癌研究的一种便捷可行的方法
Pei-Fen Zhang,Xiao-Hui Zheng,Xi-Zhao Li et al.
Pei-Fen Zhang et al.
Background: Tissue specimens for nasopharyngeal carcinoma (NPC) research are scarce because of sampling difficulties. Previous studies have suggested non-invasive nasopharyngeal brushing as an effective sampling method fo...
Efficacy of the hypoxia-activated prodrug evofosfamide (TH-302) in nasopharyngeal carcinoma in vitro and in vivo [0.03%]
低氧活化前药evofosfamide（TH-302）对鼻咽癌的体内和体外疗效研究
Yan Huang,Ying Tian,Yuanyuan Zhao et al.
Yan Huang et al.
Background: Tumor hypoxia is considered an important factor in metastasis and disease relapse. Evofosfamide is a hypoxia-activated prodrug that selectively targets the hypoxic regions of solid tumors. As hypoxia-inducible...
Effect of induction chemotherapy with cisplatin, fluorouracil, with or without taxane on locoregionally advanced nasopharyngeal carcinoma: a retrospective, propensity score-matched analysis [0.03%]
含顺铂、氟尿嘧啶和/或紫杉醇诱导化疗对局部区域晚期鼻咽癌疗效的倾向性匹配病例分析研究
Guo-Ying Liu,Xing Lv,Yi-Shan Wu et al.
Guo-Ying Liu et al.
Background: Available data in the literature comparing different induction chemotherapy (IC) regimens on locoregionally advanced nasopharyngeal carcinoma (NPC) are scarce. The purpose of the present study was to evaluate ...
Observational Study
Cancer communications (London, England). 2018 May 10;38(1):21. DOI:10.1186/s40880-018-0283-2 2018
Selection of candidates for surgery as local therapy among early-stage small cell lung cancer patients: a population-based analysis [0.03%]
早期小细胞肺癌患者选择手术作为局部治疗的病人的群体研究分析
Kaiqi Jin,Kaixuan Zhang,Feng Zhou et al.
Kaiqi Jin et al.
Background: Surgery and radiotherapy are considered local therapies for small cell lung cancer (SCLC). The present study aimed to select candidates for surgery as local therapy among patients with stage I or II SCLC, base...