A novel nomogram individually predicting disease-specific survival after D2 gastrectomy for advanced gastric cancer [0.03%]
一种新颖的列线图可单独预测进展期胃癌行D2胃切除术后特异性生存率
Wei Wang,Zhe Sun,Jing-Yu Deng et al.
Wei Wang et al.
Background: Few studies have shown nomograms that may predict disease-specific survival (DSS) probability after curative D2 gastrectomy for advanced gastric cancer (AGC), particularly among Chinese patients. This study so...
Multicenter Study
Cancer communications (London, England). 2018 May 15;38(1):23. DOI:10.1186/s40880-018-0293-0 2018
New insights from the widening homogeneity perspective to target intratumor heterogeneity [0.03%]
从日益增多的一致性角度出发的新见解，以应对肿瘤内的异质性
Mengying Tong,Ziqian Deng,Xiaolong Zhang et al.
Mengying Tong et al.
Precision medicine has shed new light on the treatment of heterogeneous cancer patients. However, intratumor heterogeneity strongly constrains the clinical benefit of precision medicine. Thus, rethinking therapeutic strategies from a differ...
Yaran Du,Ting Lu,Song Huang et al.
Yaran Du et al.
Background: Extracranial metastasis (ENM) of meningiomas is extremely rare, and typically occurs several years after a primary tumor is diagnosed. However, the genetic changes underlying ENM events have not yet been inves...
Long-term outcome of a moderately hypofractionated, intensity-modulated radiotherapy approach using an endorectal balloon for patients with localized prostate cancer [0.03%]
适度低分割强度调控放疗结合肛内模针对局部前列腺癌患者长期疗效研究
Bin S Teh,Gary D Lewis,Weiyuan Mai et al.
Bin S Teh et al.
Background: Technical advances in radiotherapy delivery have simultaneously enabled dose escalation and enhanced bladder and rectal sparing. However, the optimal radiation fractionation regimen for localized prostate canc...
Integrative analysis of gene expression profiles reveals specific signaling pathways associated with pancreatic duct adenocarcinoma [0.03%]
基因表达谱整合分析发现与胰腺导管腺癌相关的特异性信号通路
Jun Li,Wenle Tan,Linna Peng et al.
Jun Li et al.
Background: Pancreatic duct adenocarcinoma (PDAC) remains a major health problem because conventional cancer treatments are relatively ineffective against it. Microarray studies have linked many genes to pancreatic cancer...
Ultrasound-guided fine needle aspiration of retropharyngeal lymph nodes after radiotherapy for nasopharyngeal carcinoma: a novel technique for accurate diagnosis [0.03%]
放射治疗后经超声引导的鼻咽癌后咽淋巴结细针穿刺活检新技术可提高诊断准确性
Long-Jun He,Chuanbo Xie,Yin Li et al.
Long-Jun He et al.
Background: Enlarged retropharyngeal lymph nodes (RLNs) are very common in patients with nasopharyngeal carcinoma (NPC) undergoing radiotherapy. The most suitable treatment option for enlarged RLNs depends on the patholog...
Aldolase A promotes proliferation and G1/S transition via the EGFR/MAPK pathway in non-small cell lung cancer [0.03%]
丙酮酸醛缩酶A通过EGFR/MAPK途径促进非小细胞肺癌的增殖和G1/S期转换
Hailu Fu,Huijun Gao,Xiaoyu Qi et al.
Hailu Fu et al.
Background: Our previous study demonstrated that aldolase A (ALDOA) is overexpressed in clinical human lung squamous cell carcinoma and that ALDOA promotes epithelial-mesenchymal transition and tumorigenesis. The present ...
Cardiotoxicity of 5-fluorouracil and capecitabine in Chinese patients: a prospective study [0.03%]
中国人群替加氟和卡培他滨的心脏毒性观察性研究
Jianjun Peng,Chao Dong,Chang Wang et al.
Jianjun Peng et al.
Background: 5-Fluorouracil (5-FU) and capecitabine-associated cardiotoxicity ranging from asymptomatic electrocardiography (ECG) abnormalities to severe myocardial infarction has been reported in a number of studies, but ...
Multicenter Study
Cancer communications (London, England). 2018 May 11;38(1):22. DOI:10.1186/s40880-018-0292-1 2018
Xenograft tumors derived from malignant pleural effusion of the patients with non-small-cell lung cancer as models to explore drug resistance [0.03%]
恶性胸腔积液异种移植瘤模型用于探索非小细胞肺癌药物耐药机制
Yunhua Xu,Feifei Zhang,Xiaoqing Pan et al.
Yunhua Xu et al.
Background: Non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations or anaplastic lymphoma kinase (ALK) fusions show dramatic responses to specific tyrosine kinase inhibitors (TK...