Kaizhong Lu,Chandra Sugiarto Wijaya,Qinghua Yao et al.
Kaizhong Lu et al.
Copper is an essential micronutrient in the human body, mainly acting as a crucial cofactor required for a wide range of physiological processes across nearly all cell types. Recent advances revealed that tumor cells seize copper to fulfill...
Circulating tumor cells share RNA modules with early embryo trophectoderm and with metastatic cancer [0.03%]
循环肿瘤细胞与早期胚胎滋养层和转移性癌共有的RNA模块
Stefano Volinia,Anna Terrazzan,Tomasz S Kaminski et al.
Stefano Volinia et al.
Loss of SMARCB1 evokes targetable epigenetic vulnerabilities in epithelioid sarcoma [0.03%]
SMARCB1丢失引发上皮样肉瘤中的表观遗传学弱点
Jia Xiang Jin,Fabia Fuchslocher,Martha Carreno-Gonzalez et al.
Jia Xiang Jin et al.
Inhibition of mTOR attenuates the initiation and progression of BRCA1-associated mammary tumors [0.03%]
抑制mTOR可减轻BRCA1相关乳腺肿瘤的发生和发展
Hye Jung Baek,Geun Hee Han,Eun Joo Cho et al.
Hye Jung Baek et al.
Efficacy and safety of KN026 and docetaxel for HER2-positive breast cancer: a phase II clinical trial [0.03%]
抗HER2阳性乳腺癌新药KN026联合白蛋白紫杉醇Ⅱ期临床研究疗效和安全性分析
Jianli Ma,Jingxuan Wang,Ting Xu et al.
Jianli Ma et al.
Background: The standard first-line treatment for human epidermal growth factor receptor 2 (HER2)-positive recurrent/metastatic breast cancer currently includes pertuzumab plus trastuzumab and docetaxel. This study aimed ...
Bioequivalence of alternative pembrolizumab dosing regimens: current practice and future perspectives [0.03%]
帕博利珠单抗给药方案的生物等效性：当前实践与未来展望
Ruben Malmberg,Bram C Agema,Maaike M Hofman et al.
Ruben Malmberg et al.
Single-cell transcriptomics and epigenomics point to CD58-CD2 interaction in controlling primary melanoma growth and immunity [0.03%]
单细胞转录组和表观基因组揭示CD58-CD2相互作用控制原发性黑色素瘤生长及免疫反应
Antonia Stubenvoll,Maria Schmidt,Johanna Moeller et al.
Antonia Stubenvoll et al.
Training the synergy between Bacillus Calmette-Guérin and immune checkpoint-blocking antibodies in bladder cancer [0.03%]
训练卡介苗和免疫检查点阻断抗体在膀胱癌中的协同作用
Renate Pichler,Martin Thurnher
Renate Pichler
Efficacy and safety of first-line sintilimab plus anlotinib versus chemotherapy for metastatic non-small cell lung cancer: a phase II, open-label, randomized controlled trial [0.03%]
特瑞普利单抗联合阿帕替尼对比化疗治疗驱动基因阴性晚期非小细胞肺癌患者的一项开放、随机Ⅱ期临床研究
Tianqing Chu,Hua Zhong,Zhuang Yu et al.
Tianqing Chu et al.
Background: The prognosis for non-small cell lung cancer (NSCLC) patients treated with standard platinum-based chemotherapy was suboptimal, with safety concerns. Following encouraging results from a preliminary phase I st...
To what extent is the association between obesity and colorectal cancer risk mediated by systemic inflammation? [0.03%]
肥胖通过全身性炎症与结直肠癌风险之间的关联程度有多大？
Fatemeh Safizadeh,Marko Mandic,Michael Hoffmeister et al.
Fatemeh Safizadeh et al.