VDAC1 at the crossroads of cell metabolism, apoptosis and cell stress [0.03%]
位于细胞代谢、凋亡和压力交叉点的VDAC1蛋白质
Varda Shoshan-Barmatz,Eduardo N Maldonado,Yakov Krelin
Varda Shoshan-Barmatz
This review presents current knowledge related to VDAC1 as a multi-functional mitochondrial protein acting on both sides of the coin, regulating cell life and death, and highlighting these functions in relation to disease. It is now recogni...
Simonetta Camandola
Simonetta Camandola
Astrocytes have historically been considered structural supporting cells for neurons. Thanks to new molecular tools, allowing specific cell ablation or over-expression of genes, new unexpected astrocytic functions have recently been unveile...
A game of substrates: replication fork remodeling and its roles in genome stability and chemo-resistance [0.03%]
重塑复制叉及其在基因组稳定性和化疗抗性中的作用
Julia Sidorova
Julia Sidorova
During the hours that human cells spend in the DNA synthesis (S) phase of the cell cycle, they may encounter adversities such as DNA damage or shortage of nucleotides. Under these stresses, replication forks in DNA may experience slowing, s...