Machine learning-assisted stiffness prediction in high-cell-density bioprinting [0.03%]
机器学习辅助高细胞密度生物打印中的刚度预测
Jiaao Guan,Yazhi Sun,Emmie J Yao et al.
Jiaao Guan et al.
Bioprinting of cell-laden hydrogels is a rapidly growing field in tissue engineering. The advent of digital light processing (DLP) three-dimensional (3D) bioprinting technique has revolutionized the fabrication of complex 3D structures. By ...
An oxygenating colloidal bioink for the engineering of biomimetic tissue constructs [0.03%]
一种用于仿生组织构建工程的增氧胶体型生物墨水
Seol-Ha Jeong,Jarno Hiemstra,Patrick V Blokzijl et al.
Seol-Ha Jeong et al.
Ensuring a sufficient oxygen supply is pivotal for the success of bioprinting applications since it fosters tissue integration and natural regeneration. Variation in oxygen concentration among diverse tissues necessitates the precise recrea...
Jack F Murphy,Martha Lavelle,Lisa Asciak et al.
Jack F Murphy et al.
As we navigate the transition from the Fourth to the Fifth Industrial Revolution, the emerging fields of biomanufacturing and biofabrication are transforming life sciences and healthcare. These sectors are benefiting from a synergy of synth...
Design and Realization of Lung Organoid Cultures for COVID-19 Applications [0.03%]
设计和实现用于COVID-19应用的肺类器官培养
Bing Ren,Tryanni R Chiaravalloti,Nadine L Belony et al.
Bing Ren et al.
Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been spreading globally and threatening public health. Advanced in vitro models that recapitulate the architecture and func...
A facile strategy for tuning the density of surface-grafted biomolecules for melt extrusion-based additive manufacturing applications [0.03%]
一种调节表面接枝生物分子密度以适应熔融挤出基增材制造应用的简便策略
I A O Beeren,G Dos Santos,P J Dijkstra et al.
I A O Beeren et al.
Melt extrusion-based additive manufacturing (ME-AM) is a promising technique to fabricate porous scaffolds for tissue engineering applications. However, most synthetic semicrystalline polymers do not possess the intrinsic biological activit...
Biofabrication of nanocomposite-based scaffolds containing human bone extracellular matrix for the differentiation of skeletal stem and progenitor cells [0.03%]
一种用于骨骼干细胞和祖细胞分化的含人骨基质的纳米复合支架的生物制造法
Yang-Hee Kim,Janos M Kanczler,Stuart Lanham et al.
Yang-Hee Kim et al.
Autograft or metal implants are routinely used in skeletal repair. However, they fail to provide long-term clinical resolution, necessitating a functional biomimetic tissue engineering alternative. The use of native human bone tissue for sy...
Organoids revealed: morphological analysis of the profound next generation in-vitro model with artificial intelligence [0.03%]
类器官揭秘：人工智能驱动的下一代三维细胞培养模型形态学分析
Xuan Du,Zaozao Chen,Qiwei Li et al.
Xuan Du et al.
In modern terminology, "organoids" refer to cells that grow in a specific three-dimensional (3D) environment in vitro, sharing similar structures with their source organs or tissues. Observing the morphology or growth characteristics of org...
Microcapillary cell extrusion deposition with picolitre dispensing resolution [0.03%]
微毛细管细胞挤出沉积及皮升分配分辨率
Saeed Fathi,Iek Man Lei,Yang Cao et al.
Saeed Fathi et al.
Extrusion-based cell deposition has become a prominent technique for expanding bioprinting applications. However, the associated print resolution in the order of nanolitre or above has been a limiting factor. The demand for improving print ...
In vivo evaluation of additively manufactured multi-layered scaffold for the repair of large osteochondral defects [0.03%]
用于修复大型软骨下缺陷的多层支架的体内评价
Maryam Tamaddon,Gordon Blunn,Rongwei Tan et al.
Maryam Tamaddon et al.
The repair of osteochondral defects is one of the major clinical challenges in orthopaedics. Well-established osteochondral tissue engineering methods have shown promising results for the early treatment of small defects. However, less succ...
Bioreactor design and validation for manufacturing strategies in tissue engineering [0.03%]
组织工程制造策略的生物反应器设计与验证方法
Diana Lim,Eric S Renteria,Drake S Sime et al.
Diana Lim et al.
The fields of regenerative medicine and tissue engineering offer new therapeutic options to restore, maintain or improve tissue function following disease or injury. To maximize the biological function of a tissue-engineered clinical produc...