GnRH pulse frequency is decoded by distinct Gαs- and Gαq/11-mediated signaling pathways in gonadotropes in vitro [0.03%]
Gs-和Gq/11介导的信号通路解码促性腺激素细胞中的GNRH脉冲频率
George A Stamatiades,Iain R Thompson,Han Kyeol Kim et al.
George A Stamatiades et al.
Purpose: Pulsatile gonadotropin-releasing hormone (GnRH) secretion differentially regulates follicle-stimulating hormone β-subunit (Fshb) expression according to pulse frequency; however, the mechanisms by which pituitar...
Intrafollicular activin-A, inhibin-B, and follistatin are associated with in vitro fertilization outcomes in subfertile women [0.03%]
卵泡内活化素A、抑制素B和抑素与不孕女性体外受精结局相关性研究
Dimitrios Karayiannis,Roxane Tenta,Meropi D Kontogianni et al.
Dimitrios Karayiannis et al.
Purpose: The follicular microenvironment strongly influences oocyte and embryo quality and therefore plays a critical role in assisted reproduction therapy outcomes. This study prospectively evaluated the association betw...
A rare case of pheochromocytoma-induced reverse Takotsubo cardiomyopathy presenting as a catecholaminergic crisis [0.03%]
儿茶酚胺型危象罕见病例—倒置应激性心肌病（Tako-Tsubo心肌病）疑似肾上腺嗜络细胞瘤所致
Foteini Petrea,Ioannis Petropoulos,Foteini Thanasoula et al.
Foteini Petrea et al.
Purpose: Pheochromocytoma is a rare neuroendocrine tumor that may present with atypical and potentially life-threatening cardiovascular manifestations due to catecholamine excess. Reverse Takotsubo cardiomyopathy, a disti...
Hungry, hungry bones: electrolyte abnormalities in the presence of severe malnutrition [0.03%]
饥肠辘辘的骨头：重度营养不良下的电解质紊乱
Eva M Goren,Stephanie N Ferrin,Sowmya Krishnan et al.
Eva M Goren et al.
Severe malnutrition in the presence of child maltreatment and other specified feeding or eating disorder (OSFED) can lead to significant effects on bones. We present a case of severe malnutrition from child maltreatment that developed into ...
Baseline TSH within reference range and incident thyroid dysfunction in cancer patients: a retrospective cohort study [0.03%]
基于癌症患者的回顾性队列研究正常TSH范围内的甲状腺功能障碍发生率
Yin Xia,Bingli Liu,Qian Li et al.
Yin Xia et al.
Purpose: Whether baseline thyrotropin (TSH) within the reference range predicts thyroid dysfunction in cancer patients remains unclear. We evaluated this association in hospitalized cancer patients with normal baseline th...
Genetic risk factors for diabetic retinopathy in the Greek population: a review of key gene polymorphisms [0.03%]
希腊人群中糖尿病视网膜病变的遗传危险因素：关键基因多态性的综述
Nikolaos Gouliopoulos,Maria Arfara,Spyros Sapounas et al.
Nikolaos Gouliopoulos et al.
Diabetic retinopathy (DR) is one of the most common microvascular complications of diabetes mellitus and a leading cause of visual impairment among adults worldwide. While hyperglycemia and metabolic dysregulation are recognized contributor...
Bulent Okan Yildiz,Mirco Armenti,Maria Luisa Brandi et al.
Bulent Okan Yildiz et al.
The 13th Annual EndoBridge Meeting took place in Antalya, Türkiye, from October 23 to 26, 2025. Accredited by the European Council, the congress delivered a comprehensive scientific program combining state-of-the-art lectures with interact...
Efficacy and safety of osilodrostat in patients with ectopic Cushing's syndrome [0.03%]
异位库欣综合征患者使用钾柳斯朵治疗的疗效和安全性研究
Marta Araujo-Castro,Oriana Arroyo-Ripoll,Jorge Contreras-Saldarriaga et al.
Marta Araujo-Castro et al.
Objective: To analyze the efficacy and safety of osilodrostat in patients with ectopic Cushing's syndrome (ECS) in real-world studies. Methods: ...
A novel homozygous thyroglobulin gene variant presenting with massive congenital goiter and neonatal airway obstruction [0.03%]
一个新的同基因甲状腺球蛋白基因变异表现为巨大的先天性甲状腺肿和新生儿气道阻塞
Ayşe Anık,Kübra Şen Küçük,Selvin Öztürk et al.
Ayşe Anık et al.
Congenital hypothyroidism due to thyroid dyshormonogenesis is a rare inherited disorder that may present with goiter of variable severity. Massive congenital goiter causing life-threatening respiratory distress at birth is exceptionally unc...
Lipidomics and proteomics in MASLD: reading the molecular script toward precision therapeutics [0.03%]
MASLD脂质组学和蛋白质组学：迈向精确诊疗的分子谱书写读解
Anna Sofia Germanidou,Theocharis Koufakis
Anna Sofia Germanidou
Metabolic dysfunction-associated steatotic liver disease (MASLD) is increasingly recognized as a multisystem disorder characterized by complex metabolic, inflammatory, and fibrogenic interactions. Advances in lipidomics and proteomics have ...