Triple energy transfer-enabled dearomative cycloaddition/rearrangement cascade of bicyclic azaarenes to structurally complex products [0.03%]
三重能量转移促进的 bicyclic azaarenes 的去芳构化环加成/重排串联反应形成结构复杂的产物
Preeti Chahar,Utpal Kundu,Subhabrata Dutta et al.
Preeti Chahar et al.
Pyridine-fused, C(sp 3)-rich bridged frameworks are privileged scaffolds in natural products and pharmaceutical compounds, yet their synthesis remains a formidable challenge due to prevailing step-intensive routes. Energy transfer (EnT)-cat...
Conformation-driven C3-C(sp 3)-H arylation of saturated azacycles using Pd catalyst [0.03%]
钯催化饱和氮杂环的构象决定的C3-芳基化反应
Chia-Yu Chen,Zhoulong Fan,Daniel A Strassfeld et al.
Chia-Yu Chen et al.
Directed Pd-catalysed site-selective C(sp 3)-H activation offers an effective route to functionalized amines that are highly valued yet synthetically challenging in drug discovery. Despite the central importance of diverse saturated azacycl...
Site-selective Ru-catalysed saturation of unactivated arenes via directed 6π activation [0.03%]
导向的6π活化介导的位点选择性钌催化非活化芳烃饱和反应
Congjun Yu,Linda Yiu,Zining Zhang et al.
Congjun Yu et al.
The directing group-based strategy has been highly effective for site-selective functionalization of alkenes, carbonyls, C-H bonds, C-C bonds, etc., but not yet known for unactivated aromatic π-systems. On the other hand, catalytic hydroge...
Xiangdong Xu,William C Howland,Daniel Martín-Yerga et al.
Xiangdong Xu et al.
Thermochemical redox catalysis is critical to a wide array of key chemical transformations and can proceed via the coupling of two electrochemical half-reactions. This electrochemical mechanism is exemplified by the platinum-catalysed aerob...
Structural insights into metallocluster trafficking in the nitrogenase assembly scaffold NifEN [0.03%]
氮固定酶生物合成支架NifEN中金属辅基簇动态传递的结构洞察
Bryan Neumann,Kristal A Brandon,Robert Quechol et al.
Bryan Neumann et al.
Nitrogenase catalyses small-molecule activation, and has great relevance to agronomy, environment and energy. Understanding the assembly of the complex nitrogenase cofactor is a decades-long goal in the field, and structural insights into t...
Enantioselective Difluoromethylation of Unactivated Alkyl Halides via a Formal Nickel(II/IV) Cycle [0.03%]
手性未活化烷基卤代物的差向异构体选择性二氟甲基化镍(ii/iv)催化循环反应
Xian Zhao,Lingfeng Yin,Chia-Jung Yang et al.
Xian Zhao et al.
Nickel-catalysed enantioconvergent cross-coupling has emerged as a key strategy for constructing stereochemically defined C(sp3) centres. However, the reliance on nickel(I)/nickel(III) catalytic cycles has limited the range of compatible al...
Merging photoredox with metalloenzymatic catalysis for enantioselective decarboxylative C(sp3)‒N3 and C(sp3)‒SCN bond formation [0.03%]
将光氧化还原与金属酶催化结合用于映异构体选择性脱羧形成C(sp3)‒N3和C(sp3)‒SCN键反应中
Jinyan Rui,Xinpeng Mu,Jordi Soler et al.
Jinyan Rui et al.
The scope of nature's catalytic abilities has been expanded by recent advancements in biocatalysis to include synthetic transformations with no biological equivalent. However, these newly introduced catalytic functions only represent a smal...
Unveiling active sites and the cooperative role of non-thermal plasma and copper-zinc catalysts in the hydrogenation of CO2 to methanol [0.03%]
非热等离子体和铜锌催化剂在二氧化碳加氢制甲醇中的活性位点及其协同作用机制研究
Shanshan Xu,Matthew E Potter,Raquel Simancas et al.
Shanshan Xu et al.
Methanol synthesis via non-thermal plasma (NTP) catalytic CO2 hydrogenation provides a sustainable approach to chemical and fuel production with potential in carbon emissions reduction. However, the underlying mechanisms remain unclear. Her...
Wenzhen Fu,Yang Yang
Wenzhen Fu
Engineering protein catalysts represents an attractive approach for enantioselective energy transfer photochemistry. Now, combining a genetically encoded photosensitizer in the protein catalyst and a judiciously selected triplet quenchers t...
Excited-state configuration controls the ability of nitroarenes to act as energy transfer catalysts [0.03%]
激发态构型控制硝基芳烃的作用能量转移催化剂的能力
Martin Rihtaršič,Byeongseok Kweon,Piotr T Błyszczyk et al.
Martin Rihtaršič et al.
Energy transfer (EnT) catalysis enables the selective population of triplet excited states without previous singlet excitation, thus eliminating the need for high-energy irradiation. Traditionally, EnT catalysis has been approached by devel...