Olfactory enrichment mitigates delayed neurocognitive recovery after major orthopaedic surgery in older patients: A randomised controlled trial [0.03%]
Xinchun Mei,Zihan Ni,Shiyu Zhong et al.
Xinchun Mei et al.
Background: Delayed neurocognitive recovery (dNCR) is a prevalent complication in older patients undergoing surgery. It may progress to long-term cognitive impairment and increase the risk of Alzheimer's disease. ...
Global burden, risk factors and projections of self-harm mortality in adults aged 65+ years: A 60-year trend analysis from the Global Burden of Disease Study 2021 [0.03%]
全球自杀负担、风险因素及老年人群自杀死亡率预测:来自全球疾病负担研究(2021)的60年趋势分析(65岁以上人群)
Jinjie Xu,Yiman Guo,Zizhao Feng et al.
Jinjie Xu et al.
Background: Epidemiological research on self-harm in older adults (aged 65+ years) remains scarce despite its growing public health significance amid global ageing. ...
Dynamic trajectories of neuropsychiatric symptoms predict Alzheimer's disease risk and clinical phenotypes [0.03%]
神经精神症状的动态轨迹预测阿尔茨海默病风险和临床表型
Wenzheng Liu,Yan Wang,Yuhang Shi et al.
Wenzheng Liu et al.
Background: Neuropsychiatric symptoms (NPS) may serve as early predictors of Alzheimer's disease (AD). However, NPS evolve over time, and most existing studies have relied on single or sparse assessments that do not captu...
Causal machine learning analysis identifies subpopulations most likely to benefit from healthy lifestyles for cognitive outcomes [0.03%]
因果机器学习分析确定了最有可能从健康生活方式中受益的认知结果亚群体
Youjin Jiang,Yi Ding,Qiuyu Cao et al.
Youjin Jiang et al.
Background: With dementia posing an escalating public health threat, adopting healthy lifestyles is increasingly recognised as a key preventive measure for preserving cognitive function. However, the effect of multidomain...
Shared genetic variants across substance use disorders implicate common neurobiological pathways, a genome-wide mixed methods study [0.03%]
横断面基因组学混合研究发现多种物质使用障碍共有的遗传变异,涉及常见的神经生物学通路
Børge Holen,Zillur Rahman,Alexey A Shadrin et al.
Børge Holen et al.
Background: Substance use disorders (SUDs) are highly heritable, but the extent of shared and distinct genetic architecture across different SUDs is unclear. ...
Sevoflurane versus propofol and the long-term risk of attention-deficit/hyperactivity disorder in children [0.03%]
异丙酚与七氟醚与儿童注意缺陷多动障碍长期发病风险的关系研究
Mingyang Sun,Yangyang Wang,Yuqin Tang et al.
Mingyang Sun et al.
Background: Preclinical studies have shown that volatile anaesthetics, particularly sevoflurane, can disrupt neurodevelopment by inducing neuronal apoptosis, neuroinflammation and altered synaptic plasticity during critic...
Correspondence between morphological similarity of the left lateral orbitofrontal cortex and neurotransmitter systems in adolescent males with autism [0.03%]
自闭症青少年左额下回脑区形态相似性及其神经递质系统的关系研究
Huashuang Zhang,Junle Li,Chensheng Hou et al.
Huashuang Zhang et al.
Background: Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by pronounced heterogeneity in brain structure, which limits the development of targeted interventions. Morphological brain networks (MBN...
A genome-wide association study of post-traumatic stress disorder in traumatised Chinese populations [0.03%]
中国创伤人群创伤后应激障碍的全基因组关联研究
Kunlin Zhang,Mingyue Gao,Chengqi Cao et al.
Kunlin Zhang et al.
The effect of 6 Hz transcranial alternating current stimulation over the prefrontal cortex on reward learning in men with methamphetamine use disorder: A pilot randomised double-blind trial [0.03%]
针对甲基苯丙胺使用障碍男性的前额叶6Hz经颅交流电刺激对奖赏学习影响的随机双盲试验——一项试点研究
Qianlan Yin,Tianzhen Chen,Yan Long et al.
Qianlan Yin et al.
Resting-state connectivity and tobacco smoking in clinical high-risk for psychosis (NAPLS-3) [0.03%]
临床高危期患者静息态脑网络连接与吸烟行为的关系(NAPLS-3)
Merel Koster,Marieke van der Pluijm,Romy Veelers et al.
Merel Koster et al.
Background: Smoking is highly prevalent among people at clinical high-risk for psychosis (CHR-P) and is associated with poorer clinical outcomes. Large-scale brain networks have been linked to both psychosis and tobacco s...