Aurélie Hautefort,Anna Pfenniger,Brenda R Kwak
Aurélie Hautefort
Gap junctions are essential for intercellular crosstalk in blood and lymphatic vasculature. These clusters of intercellular channels ensure direct communication among endothelial cells and between endothelial and smooth muscle cells, and th...
Environmental stress influences mitochondrial metabolism in vascular cells: consequences for angiogenesis [0.03%]
环境压力影响血管细胞的线粒体代谢：对血管生成的影响
T Scott Bowen,Stuart Egginton
T Scott Bowen
While the important and varied roles that vascular cells play in both health and disease is well recognised, the focus on potential therapeutic targets continually shifts as new players emerge. Here, we outline how mitochondria may be viewe...
Tomasz Jadczyk,Guido Caluori,Wojciech Wojakowski et al.
Tomasz Jadczyk et al.
Nanotechnology and stem cells are one of the most promising strategies for clinical medicine applications. The article provides an up-to-date view on advances in the field of regenerative and targeted vascular therapies describing a molecul...
James T Pearson,Mikiyasu Shirai,Vijayakumar Sukumaran et al.
James T Pearson et al.
Ghrelin is a small peptide with important roles in the regulation of appetite, gut motility, glucose homeostasis as well as cardiovascular protection. This review highlights the role that acyl ghrelin plays in maintaining normal endothelial...
HMGB1-mediated apoptosis and autophagy in ischemic heart diseases [0.03%]
高迁移率族蛋白box1在缺血性心脏病所介导的细胞凋亡和自噬中的作用
Eleonora Foglio,Laura Pellegrini,Antonia Germani et al.
Eleonora Foglio et al.
Acute myocardial infarction (MI) and its consequences are the most common and lethal heart syndromes worldwide and represent a significant health problem. Following MI, apoptosis has been generally seen as the major contributor of the cardi...
Carlo Dal Lin,Francesco Tona,Elena Osto
Carlo Dal Lin
The heart and the immune system are highly integrated systems cross-talking through cytokines, hormones and neurotransmitters. Their balance can be altered by numerous physical or psychological stressors leading to the onset of inflammation...
MicroRNAs orchestrating senescence of endothelial and vascular smooth muscle cells [0.03%]
microRNA调控血管内皮细胞和血管平滑肌细胞的衰老过程
Ornella Colpani,Gaia Spinetti
Ornella Colpani
During organism aging, the process of cellular senescence is triggered by critical stressors such as DNA damage, oncogenes, oxidative stress, and telomere erosion, and vascular cells are not exempted. Senescent cells stop proliferating but ...
Plasticity of vascular resident mesenchymal stromal cells during vascular remodeling [0.03%]
血管重建过程中血管驻留间质干细胞的可塑性
Xuechong Hong,Wenduo Gu
Xuechong Hong
Vascular remodeling is a complex and dynamic pathological process engaging many different cell types that reside within the vasculature. Mesenchymal stromal/stem cells (MSCs) refer to a heterogeneous cell population with the plasticity to d...
Stephen P Gray,Ajay M Shah,Ioannis Smyrnias
Stephen P Gray
The heart relies on complex mechanisms that provide adequate myocardial oxygen supply in order to maintain its contractile function. At the cellular level, oxygen undergoes one electron reduction to superoxide through the action of differen...
Sandra Neumann,Elena G Milano,Chiara Bucciarelli-Ducci et al.
Sandra Neumann et al.
This mini review provides a concise overview of imaging techniques that are currently used to image the atheroscletoric plaque in the carotid artery in vivo. The main techniques include ultrasound imaging, X-ray imaging, magnetic resonance ...