Recent advancements and limitations of intestinal organoids for clinical applications [0.03%]
类器官在临床应用中的最新进展和局限性：以肠类器官为例
Md Zahirul Islam Khan,Somrita Roy,Soumya Nair et al.
Md Zahirul Islam Khan et al.
Colorectal cancer (CRC) is one of the leading causes of cancer-related deaths worldwide, and there has been a concerning rise in its incidence among younger populations. Although there have been significant advances in molecular characteriz...
Tissue Engineering Strategies for Annulus Fibrosus Repair: A Scoping Review of Repair Methods, Animal Models, and Evaluation Techniques [0.03%]
纤维环修复的组织工程策略：修复方法、动物模型和评价技术的综述研究
Lipeng Song,Zhaozhen Liu,Akin Atas et al.
Lipeng Song et al.
Background
Intervertebral disc (IVD) degeneration is a common chronic disease and may lead to disc herniation. Microdiscectomy removes the herniated tissue, but cannot address altered IVD biomechanics or restore annulus fibrosus (AF) st...
Tomy Varghese
Tomy Varghese
Lagrangian strain imaging requires knowledge of the prior state of the deformation at its very core and can be accomplished if all three components of the displacement vector field can be accurately estimated. However, most ultrasound imagi...
Novel aptamers targeting heparan sulfate for delivery of RNA therapeutics in Alzheimer's disease [0.03%]
针对阿尔茨海默病RNA治疗的新型肝素硫酸盐靶向适配体
Arshad Mehmood,Amir Zaman Shah,Jesus Alejandro Martinez Juarez et al.
Arshad Mehmood et al.
Heparan sulfate (HS) proteoglycans are abundant, sulfation-patterned glycosaminoglycans on brain cells and the neurovascular unit that interact with amyloid-β (Aβ) and tau, aggregate and propagate proteopathic species, and modulate cellul...
A Perspective on Neuromechanical Biomarkers for Neurorehabilitation: Towards Reliable Assessment in Research and Clinical Practice [0.03%]
神经康复中神经机械生物标志物的视角：研究与临床实践中的可靠评估展望
Florencia Garro,Indya Ceroni,Andrea D&#x;Avella et al.
Florencia Garro et al.
Effective neurorehabilitation necessitates a reliable assessment of the patient's sensorimotor status. Such assessment guides clinical decision-making and supports the evaluation of novel interventions. Yet, despite technological progress, ...
Assessing the Relevance of Biosignal-Controlled Robotic Rehabilitation Technologies: A Systematic Review [0.03%]
基于生物信号控制的机器人康复技术的相关性评估：系统评价研究论文
Vittorio Santoriello,Giuseppe Cesarelli,Fanny Ficuciello Ficuciello et al.
Vittorio Santoriello et al.
Technology is transforming rehabilitative medicine by enhancing accessibility and personalisation. Robot-assisted rehabilitation uses robotic systems for recovery from physical and neurological impairments, enabling intensive, repetitive tr...
Beyond the Lab: a Review on Neurophysiological Mental States Assessment in Real-World settings [0.03%]
走出实验室：实地情景下神经生理学心理状态评估的综述
Rossella Capotorto,Vincenzo Ronca,Gianluca Di Flumeri et al.
Rossella Capotorto et al.
Recent advancements in wearable, non-invasive neurophysiological sensors have increased interest in applying Human Factors (HF) research beyond controlled laboratory settings. HF research aims to objectively quantify individuals' (alone or ...
Advancement of deep learning models with whole slide image in diagnosis, subtyping and prognosis for glioma [0.03%]
基于全切片图像的深度学习模型在胶质瘤诊断、分型和预后中的进展
Ke Gui,Qiong Li,Zongyu Xie et al.
Ke Gui et al.
Gliomas are heterogeneous primary central nervous system (CNS) tumors with diverse molecular subtypes and variable prognosis. A paradigm shift in histopathology is underway as samples are digitized into whole-slide images (WSIs). Deep learn...
Viktor Dremin
Viktor Dremin
Tissue metabolism represents a complex, integrated system governing the energetic and plastic homeostasis of organs through the coordinated interaction of cellular biochemistry and systemic vascular supply. This review synthesises the funda...
Andrew Guo,Alexandra G Bell,Cameron Myhrvold
Andrew Guo
Deployable diagnostics are necessary for the control and treatment of infectious diseases, with significant unmet needs revealed during the COVID-19 pandemic. Nucleic acid diagnostics remain among the most sensitive and specific forms of de...