Jenifer Monks,Mark S Ladinsky,James L McManaman
Jenifer Monks
Milk-secreting epithelial cells of the mammary gland are functionally specialized for the synthesis and secretion of large quantities of neutral lipids, a major macronutrient in milk from most mammals. Milk lipid synthesis and secretion are...
Marcus D Kilwein,M A Welte
Marcus D Kilwein
Lipid droplets (LDs) are fat storage organelles integral to energy homeostasis and a wide range of cellular processes. LDs physically and functionally interact with many partner organelles, including the ER, mitochondria, lysosomes, and per...
Carlos Enrich,Carles Rentero,Thomas Grewal et al.
Carlos Enrich et al.
Delivery of low-density lipoprotein-derived cholesterol to the endoplasmic reticulum (ER) is essential for cholesterol homeostasis, yet the mechanism of this transport has largely remained elusive. Two recent reports shed some light on this...
Systematic prediction of FFAT motifs across eukaryote proteomes identifies nucleolar and eisosome proteins with the predicted capacity to form bridges to the endoplasmic reticulum [0.03%]
系统预测真核生物蛋白质组中的FFAT基序,确定具有向内质网形成桥梁的预测能力的核糖体和eisosome蛋白
John A Slee,Timothy P Levine
John A Slee
The endoplasmic reticulum (ER), the most pervasive organelle, exchanges information and material with many other organelles, but the extent of its inter-organelle connections and the proteins that form bridges are not well known. The integr...
Meeting Report from the 2019 "Organelle Zone" Symposium in Osaka, Japan [0.03%]
2019年日本大阪“ Organelle Zone”研讨会会议纪要
Tim P Levine,Franck Perez,Yasunori Saheki et al.
Tim P Levine et al.
On May 29 at the Osaka University Hospital, Japan, the "Organelle Zones" research grant group (see http://organellezone.org/english/) organized a one day symposium for its own members and four guest speakers, with about 60 attendees. The re...
Mitochondrial-Endoplasmic Reticulum Interplay: A Lifelong On-Off Relationship? [0.03%]
线粒体-内质网相互作用:终生的爱恨纠缠?
Corina T Madreiter-Sokolowski,Roland M Malli,Wolfgang F Graier
Corina T Madreiter-Sokolowski
This article comments recent publications that highlight an intriguing importance of specific settings in the interaction between the mitochondria and the endoplasmic reticulum to ensure cell-specific functions like the responsiveness to el...
Mitochondrial-Endoplasmic Reticulum Interplay: A Lifelong On-Off Relationship? [0.03%]
线粒体-内质网相互作用:一生的携手关系吗?
Corina T Madreiter-Sokolowski,Roland M Malli,Wolfgang F Graier
Corina T Madreiter-Sokolowski
This article comments recent publications that highlight an intriguing importance of specific settings in the interaction between the mitochondria and the endoplasmic reticulum to ensure cell-specific functions like the responsiveness to el...
Natalie Krahmer,Matthias Mann
Natalie Krahmer
Lipid droplets (LDs), important organelles for energy storage and involved in the development of metabolic disorders, are extremely dynamic and interact with many other cellular compartments to orchestrate lipid metabolism. Little is known ...
Fluorescent tools to analyse peroxisome-ER interactions in mammalian cells [0.03%]
分析哺乳动物细胞内过氧化物酶体-内质网相互作用的荧光工具
Alexa Bishop,Maki Kamoshita,Josiah B Passmore et al.
Alexa Bishop et al.
Peroxisomes and the endoplasmic reticulum (ER) cooperate extensively in lipid-related metabolic pathways, and the ER also provides phospholipids to enable the peroxisomal membrane to expand prior to division. Recently, we identified peroxis...
Emmanuelle M Bayer,Tito Calì,Francesca Giordano et al.
Emmanuelle M Bayer et al.