Tomas Knedlik,Federica Dal Bello,Marta Giacomello
Tomas Knedlik
Membrane contact sites (MCSs) are points where organelle surfaces are juxtaposed, without fusion of their membranes. Research in the MCS field has widely focused on the molecules and mechanisms that hold organelles together, known as "tethe...
Structural Organization of the Nvj3-Mdm1 Complex Reveals a Conserved Lipid-Compatible Contact Site Module [0.03%]
Nvj3-Mdm1复合物的结构组织揭示了保守的脂质兼容接触位点模块
Marwa Aboumourad,Hanaa Hariri
Marwa Aboumourad
Membrane contact sites are organized by protein assemblies that physically couple organelles and coordinate lipid metabolism, yet the structural principles that enable lipid exchange across these junctions remain poorly defined. At the nucl...
Annexin A6 Is a Novel Cytosolic Regulator of Multiple Inter-organelle Contact Sites [0.03%]
annexin a6 是多种细胞器相互作用位点的新型调节因子
Carlos Enrich,Carles Rentero,Thomas Grewal
Carlos Enrich
Annexins are a widely expressed family of multifunctional cytosolic proteins with diverse cellular roles. Recent advances have uncovered new avenues for the involvement of several annexins in membrane dynamics, suggesting a potential link t...
Genetically Encoded Tools to Monitor and Interrogate Membrane Contact Sites [0.03%]
用于监测和研究膜接触位点的基因编码工具
Yuepeng Ke,Tien-Hung Lan,Thomas Ahn et al.
Yuepeng Ke et al.
Membrane contact sites (MCSs) are dynamic subcellular compartments formed between organelles that coordinate diverse aspects of cellular communication, including signaling, metabolism, and membrane organization. Tools capable of monitoring ...
Juliane Da Graça,Dobrawa Amiri Czajkowski,Etienne Morel
Juliane Da Graça
Autophagosome biogenesis is a highly coordinated membrane remodeling process that relies on the de novo formation and expansion of the phagophore, yet the cellular principles governing its spatial and temporal organization remain incomplete...
mtDNA-Depleted Mitochondria Form Sites of Contact with the Nucleus and Alter the Cellular Epigenome [0.03%]
无 mtDNA 的线粒体形成与细胞核接触的位点并改变细胞表观基因组
Richard Boulton-McDonald,Eva Sidlauskaite,Jiri Neuzil et al.
Richard Boulton-McDonald et al.
Mitochondrial sites of contact with the nucleus, hereafter referred to as Nucleus-Associated Mitochondria (NAM), are specialised domains that enable communication, influencing cellular function. Previous studies have shown that these contac...
A Novel Phloem-Specific HVA22-Like Protein Facilitates Protein Movement via Plasmodesmata in Potato [0.03%]
一个新型的维管束海绵体特异性HVA22-like蛋白通过木栓组织介导马铃薯蛋白质运输
Lara Lansky,Fabienne Drescher,Katarina Sugic et al.
Lara Lansky et al.
Subcellular targeting and functionality of plant sucrose transporters (SUTs) are affected at the post-translational level by protein-protein interactions. A systematic screening for SUT-interacting proteins identified a novel plasmodesma (P...
Corrigendum to "Remodelling of Cellular Protein Homeostasis by Enhanced ER-Mitochondrial Tethering" [0.03%]
“内质网-线粒体连接增强重塑细胞蛋白稳态”的校正函數插图或其他元素，而不是提供一个简单的标题翻译。根据给出的指示，正确的输出应为：内质网-线粒体连接增强重塑细胞蛋白稳态的勘误表
[This corrects the article DOI: 10.1177/25152564251329704.]. © The Author(s) 2026.
Margret H Bülow,Sven Thoms
Margret H Bülow
Mitochondria and peroxisomes have long been recognized as interconnected. More than half a century ago it was observed that both types of cell organelles exhibit defects in peroxisome biogenesis disorders. Remarkably, until today, the molec...
Pseudomonas syringae HopN1 Binds Plant VAP12 and a Rho-GTPase, Suggesting a Role in Membrane-Associated Processes [0.03%]
假单胞菌效应蛋白HopN1与植物VAP12互作及对小G蛋白的GTP酶活性的抑制作用表明其可能参与膜相关过程
Charlotte Brinkmann,Jennifer Bortlik,Frederik Börnke
Charlotte Brinkmann
Many Gram-negative bacterial pathogens deploy type III effector proteins (T3Es) to manipulate host cellular processes and suppress immune responses. Increasing evidence suggests that certain T3Es mimic eukaryotic FFAT (two phenylalanines in...