Amide N-C Bond Activation: A Graphical Overview of Acyl and Decarbonylative Coupling [0.03%]
酰胺N-C键活化反应：酰基及脱羰偶联反应概述
Chengwei Liu,Michal Szostak
Chengwei Liu
This Graphical Review provides an overview of amide bond activation achieved by selective oxidative addition of the N-C(O) acyl bond to transition metals and nucleophilic acyl addition, resulting in acyl and decarbonylative coupling togethe...
Chemical Reactions of Indole Alkaloids That Enable Rapid Access to New Scaffolds for Discovery [0.03%]
用于发现的新的骨架快速合成的吲哚生物碱反应化学研究
Derek A Leas,Daniel C Schultz,Robert W Huigens rd
Derek A Leas
This graphical review provides a concise overview of indole alkaloids and chemical reactions that have been reported to transform both these natural products and derivatives to rapidly access new molecular scaffolds. Select biologically act...
Aryl Methyl Ketones: Versatile Synthons in the Synthesis of Heterocyclic Compounds [0.03%]
芳甲酮：异杂环化合物合成中的多功能合成子
Shabber Mohammed,Jason S West,Mark J Mitton-Fry
Shabber Mohammed
The synthesis of aromatic heterocycles has attracted substantial attention due to the abundance of these heterocycles in drug molecules, natural products, and other compounds of biological interest. Accordingly, there is a demand for straig...
C-H Bond Functionalization of Amines: A Graphical Overview of Diverse Methods [0.03%]
胺类化合物的C-H键功能化：多样方法的图形概述
Subhradeep Dutta,Bowen Li,Dillon R L Rickertsen et al.
Subhradeep Dutta et al.
This Graphical Review provides a concise overview of the manifold and mechanistically diverse methods that enable the functionalization of sp3 C-H bonds in amines and their derivatives. ...
Dillon R L Rickertsen,Longle Ma,Anirudra Paul et al.
Dillon R L Rickertsen et al.
Amines such as 1,2,3,4-tetrahydroisoquinoline undergo redox-neutral annulations with ortho-(nitromethyl)benzaldehyde. Benzoic acid acts as a promoter in these reactions, which involve concurrent amine α-C-H bond and N-H bond functionalizat...