Luca Boccacci,Martina Scalia,Riccardo Borzuola et al.
Luca Boccacci et al.
Frailty of the elderly is a condition that incorporates multisystem physiological age-related impairments with poor clinical and functional outcomes. Literature shows that this condition could be associated with cognitive deterioration due ...
Aerobic training conducted at different times of day in elderly patients with hypertension: a controlled trial [0.03%]
高血压老年人不同时间有氧运动干预的随机对照试验研究
Luan M Azevêdo,Natan D da Silva Junior,Gustavo F de Oliveira et al.
Luan M Azevêdo et al.
Previous data showed greater blood pressure (BP) reduction after aerobic training performed in the evening than in the morning in middle-aged hypertensive men. This study investigated whether the time of day in which aerobic training is per...
Longitudinal effects of cerebrovascular reactivity and cerebral pulsatility in cognitively intact older adults with APOE4: links with cognition [0.03%]
APOE4阳性认知正常老年人的脑血管反应性和脑脉动性的纵向效应：与认知的关系
Zacharie Potvin-Jutras,Pierre-Luc Tremblay,Hanieh Mohammadi et al.
Zacharie Potvin-Jutras et al.
The apolipoprotein E4 (APOE4) allele is the strongest genetic risk factor for Alzheimer's disease (AD) and is linked to poorer cerebrovascular health. Cerebrovascular reactivity (CVR), an indicator of vascular reserve, and cerebral pulsatil...
The effect of anthocyanins and anthocyanin-rich foods on cognitive function: a meta-analysis of randomized controlled trials [0.03%]
花青素及富含花青素食物对认知功能的影响：随机对照试验的荟萃分析研究
Agnieszka Micek,Justyna Godos,Francesca Giampieri et al.
Agnieszka Micek et al.
The rising prevalence of cognitive disorders highlights the urgent need for effective prevention strategies and therapeutic interventions. While adherence to a balanced diet has been associated with a reduced risk of cognitive decline, emer...
A novel clinical biomarker-based Physiology Healthy Aging Index and risk of all-cause and cause-specific mortality: A 20-year prospective cohort study [0.03%]
基于临床生物标志物的生理健康衰老指数和全因及特定原因死亡率的关系：一项为期20年的前瞻性队列研究
Jieun Lyu,Ji-Yun Hwang,Joong-Yeon Lim et al.
Jieun Lyu et al.
Population aging is accelerating worldwide, with 16% projected to be aged ≥ 65 years by 2050. A practical index reflecting overall aging status is needed for population-based research, as existing indices often require specialised or cogni...
The frailty mortality link in people with chronic diseases pertaining to 13 body organ systems: findings from the UK Biobank study [0.03%]
英国生物银行研究中13种器官系统慢性疾病人群的衰弱与死亡关联性分析
Justine Dastouet,Aurore Fayosse,Louis Jacob et al.
Justine Dastouet et al.
Frailty in older adults, particularly those with chronic diseases, has a robust association with risk of mortality, but whether this is the case in middle-aged adults is unclear. We examined the frailty-mortality association in middle-aged ...
Comparing rehabilitation with and without neuromuscular electrical stimulation in hospitalized older adults: Cognitive, functional, and acceptability outcomes from a pragmatic pilot study [0.03%]
神经肌肉电刺激与不进行神经肌肉电刺激的康复对照研究——一项实用主义试点研究中的认知、功能和可接受性结果分析住院老年患者
Evrim Gökçe,Gilles Loggia,Alyzée Henry et al.
Evrim Gökçe et al.
Neuromuscular electrical stimulation (NMES) is a non-invasive therapeutic approach offering targeted muscle contraction without requiring voluntary effort. This pragmatic pilot study investigated the effects of integrating NMES into usual r...
The immuno-neurological axis: association between autoimmune diseases and dementia risk [0.03%]
免疫-神经系统轴：自身免疫疾病与痴呆风险之间的联系
Wanhyung Lee,Xiaoxue Ma,Seunghyun Lee
Wanhyung Lee
Dementia is a growing global public health concern, with an increasing number of individuals affected due to the aging population. Although chronic inflammation is implicated in cognitive impairment, studies on its association with autoimmu...
Multimorbidity, frailty and polypharmacy in European and Asian patients with atrial fibrillation: a comparison of two regional prospective observational registries [0.03%]
欧洲和亚洲心房颤动患者多病共存、衰弱和多种用药的比较研究：两种区域性前瞻性观察性注册表的数据分析
Davide Antonio Mei,Marco Proietti,Giulio Francesco Romiti et al.
Davide Antonio Mei et al.
Multimorbidity, frailty, and polypharmacy are associated with worse outcomes in patients with atrial fibrillation (AF), leading to 'clinically complex' patient phenotypes. Possible differences between European and Asian patients regarding t...
Diurnal dynamics of multilayer brain networks predict cognitive trajectories in aging [0.03%]
昼夜脑多层网络的动态预测衰老中的认知变化轨迹
Kenza Bennis,Anna Canal-Garcia,Joana B Pereira et al.
Kenza Bennis et al.
Resting-state functional connectivity (rsFC) is a highly dynamic process that varies across different times of the day within each individual. Although this variability was long considered to be noise, recent evidence suggests it may allow ...