Coenzyme Q10 supplementation raises plasma levels without improving mitochondrial function in older adults [0.03%]
辅酶Q10补充对老年人大肠杆菌水平的影响及其改善线粒体功能的效果有限
Malte Schmücker,Cathrine Tranberg,Jacob Borch et al.
Malte Schmücker et al.
Mitochondrial function is important to healthy aging, as it influences energy metabolism, oxidative stress, and physical performance. With age, mitochondrial function and biosynthesis of coenzyme Q10 (CoQ10) may change. CoQ10 serves as a ke...
Liver-specific phenotypic aging, behavior and genetic risks, and long-term liver-related outcomes [0.03%]
肝脏特异性表型衰老、行为和遗传风险以及长期肝相关结局
Tianhao Wu,Chengnan Guo,Huangbo Yuan et al.
Tianhao Wu et al.
Phenotypic age, an aging indicator derived from clinical biomarkers, is associated with morbidities and mortality. However, a liver-specific phenotypic aging indicator is still lacking, and its longitudinal associations with liver-related o...
Lifetime non-relational traumatic experiences are associated with biological ageing [0.03%]
一生中的非关系创伤经历与生物衰老有关
Thole H Hoppen,Nexhmedin Morina,Monica Aas et al.
Thole H Hoppen et al.
Exposure to non-relational trauma, such as serious accidents, war or life-threatening illness, is linked to poor mental and physical health. Its relationship with biological ageing markers, however, remains underexplored. This study's aim w...
Optimizing cognitive functions in healthy older adults: a network meta-analysis of dual- and single-task interventions [0.03%]
健康老年人认知功能的优化：双重任务和单重任务干预的网络meta分析
Barbara Cazzolli,Andrea Chirico,Federica Stefanelli et al.
Barbara Cazzolli et al.
Physical and cognitive interventions, alone or combined, are recognized strategies to enhance cognitive function in healthy older adults, though their relative effectiveness remains debated. This study aimed to compare and classify the impa...
Metabolic signatures, vitamin D, and red cell distribution width in dementia risk: UK Biobank insights [0.03%]
代谢标志物、维生素D和红细胞分布宽度与痴呆症风险的关系：英国生物银行的见解
May A Beydoun,Tianyi Huang,Nicole Noren Hooten et al.
May A Beydoun et al.
Red cell distribution width (RDW), reflecting erythrocyte size variability, and serum vitamin D are emerging biomarkers for dementia. We examined the independent and joint associations of RDW and 25-hydroxyvitamin D [25(OH)D] with incident ...
Hierarchical disruption of lateral prefrontal cortex gradients in cognitive aging [0.03%]
侧前额叶皮层认知老化梯度的分层破坏
Hai-Yan Hou,Ping Wang,Sheng-Ju Guo et al.
Hai-Yan Hou et al.
The lateral prefrontal cortex (LPFC) plays a pivotal role in executive functions and exhibits a hierarchical rostro-caudal organization critical for higher-order cognition. Using connectome gradient mapping of resting-state fMRI data across...
Associations of air pollution and genetic risk and their interaction with risk of Alzheimer's disease: identification of risk loci and potential biological pathways [0.03%]
空气污染与遗传风险的关联及其与阿尔茨海默病风险相互作用的队列研究：风险位点和潜在生物学途径的识别
Shanshan Ran,Jingyi Zhang,Miao Cai et al.
Shanshan Ran et al.
Background: Air pollution is associated with Alzheimer's disease (AD), and the susceptibility of AD from air pollution may be affected by genetic characteristics, but the underlying mechanisms remain unknown. ...
DNA methylation-based surrogate markers of C-reactive protein and their associations with health-related traits [0.03%]
基于DNA甲基化的C反应蛋白替代标志物及其与健康相关表型的关系研究
Danmeng Lily Li,Allison M Hodge,Joanne Ryan et al.
Danmeng Lily Li et al.
Several methylation-based surrogate markers of C-reactive protein (mCRP) have been proposed and used to assess the risk of age-related phenotypes and construct novel ageing markers. We aimed to (i) assess the variance in plasma CRP explaine...
Tai Chi modulating multimodal connectivity patterns and cognitive function in cerebral small vessel disease [0.03%]
太极拳调制多模态连接模式和脑小血管病认知功能
Xiaoyong Zhong,Zhongpeng Dai,Liuxi Chu et al.
Xiaoyong Zhong et al.
Cerebral small vessel disease (CSVD) significantly contributes to cognitive decline and poses potential risk factors for both dementia and acute cerebrovascular events. Tai Chi has been recognized as an effective mind-body intervention for ...
Is the emerging influenza A(H3N2) K subclade a specific threat for older adults? [0.03%]
新兴的甲型流感(A-H3N2)K亚谱系会对老年人构成特定威胁吗？
Jorge Quarleri,M Victoria Delpino
Jorge Quarleri
Editorial
GeroScience. 2026 Jan 21. DOI:10.1007/s11357-026-02108-y 2026