A Randomized, Single-Dose, Single-Sequence, Two-Arm (Fasting and Fed), Open-Label Study on the Oral Pharmacokinetics of a Nanodispersible Cannabidiol Solution (150 mg/mL) [0.03%]
一项单次给药、单序列、两组(空腹和餐后)、开放标签研究,评估一种纳微乳大麻二酚溶液(150毫克/毫升)口服药代动力学的随机试验
Prasad Rao Gundugurti,Monila Nadikudi,Ramyasree Thatikonda et al.
Prasad Rao Gundugurti et al.
Introduction: Cannabidiol (CBD), a non-psychoactive phytocannabinoid, attributed to its therapeutic benefits and positive safety profile is being studied for its potential to treat various medical conditions. The low oral...
Amie J Goodin,Jeevan Jyot,Robert L Cook et al.
Amie J Goodin et al.
Effect of Cannabigerol on Sleep and Quality of Life in Veterans: A Decentralized, Randomized, Placebo-Controlled Trial [0.03%]
大麻萜酚对退伍军人睡眠和生活质量的影响:一项去中心化、随机、安慰剂对照试验
Chris R Emerson,Courtney E Webster,Eric J Daza et al.
Chris R Emerson et al.
Introduction: This decentralized, randomized, triple-blind, placebo-controlled study evaluated efficacy and safety of oral cannabigerol (CBG) in Veterans with sleep issues. ...
Juan G Perez,Liva G LaMontagne,Gabriela A Garcia et al.
Juan G Perez et al.
Background: At least 60% of individuals with anxiety disorders report sleep disturbances, which might be explained by shared physiological mechanisms, including cortisol dysregulation and executive function skills disrupt...
UK Medical Cannabis Registry: An Updated Analysis of Cannabis-Based Medicinal Products for Multiple Sclerosis [0.03%]
英国医学大麻登记处:多发性硬化症的基于大麻的药物治疗的最新分析研究报告
Yashvi Shah,Simon Erridge,Evonne Clarke et al.
Yashvi Shah et al.
Introduction: Multiple sclerosis (MS) is a neurodegenerative disease presenting with a wide range of motor, sensory, and psychiatric symptoms. Although nabiximols is licensed for MS-induced spasticity, cannabis-based medi...
Cannabis Certifications for Severe Chronic and Intractable Pain: Geographic Patterns across Pennsylvania, USA [0.03%]
美国宾夕法尼亚州大麻严重慢性难治性疼痛资格认证的地域模式分布图
Sanya K Mehta,Lorraine D Tusing,Ahmad Higazy et al.
Sanya K Mehta et al.
Introduction: Chronic pain is the most common qualifying condition found in states with legal (certified) access to medical cannabis (MC). We assessed the geographic distribution of MC certifications for severe chronic or...
Marieke Vringer,Michel Cronie,Aniek Remmerswaal et al.
Marieke Vringer et al.
Introduction: The endocannabinoid system plays a role in sleep-wake regulation. In clinical practice, people with central disorders of hypersomnolence (CDH) frequently report use of cannabis. ...
Medical Patients' Awareness, Perspectives, and Experiences with Contaminated Cannabis [0.03%]
患者对受污染大麻的意识、观点和体验
Gabriel Spandau,Jamie Loizzo,Amie Goodin et al.
Gabriel Spandau et al.
Introduction: Concerns about contamination in medical cannabis products have garnered media attention, but there is limited evidence in the literature documenting patient and consumer experiences. With growing public inte...
Peter Pressman,A Wallace Hayes,Ahmed M Hamam et al.
Peter Pressman et al.
Background: Despite significant gaps in the research literature, the integration of cannabidiols into chewing gum as a drug delivery system is a novel and promising approach for various cannabinoid therapeutic application...
The Individual and Interactive Effects of Alpha-Pinene and Delta-9-Tetrahydrocannabinol in Healthy Adults [0.03%]
健康成年人中α-蒎烯和Δ-9-四氢大麻酚的单一和交互作用效应
Lakshmi Kumar,Tory R Spindle,C Austin Zamarripa et al.
Lakshmi Kumar et al.
Introduction: Cannabis contains hundreds of chemical constituents beyond delta-9-tetrahydrocannabinol (Δ9-THC), which is thought to be the primary driver of most of its acute pharmacodynamic effects. The entourage effect...