Exploring the Associations and Molecular Impacts of miR-146a/rs2910164 and miR-196a2/rs185070757 with Rheumatoid Arthritis in a Pakistani Population [0.03%]
探讨miR-146a/rs2910164和miR-196a2/rs185070757与巴基斯坦人群类风湿关节炎的关联及分子影响
Yasir Ali,Aamir Khan,Mehran Akhtar et al.
Yasir Ali et al.
Introduction: MicroRNAs (miRNAs) are a new class of molecules that participate in post-transcriptional regulation of gene expression and hence have been reported to have a crucial role in the pathogenesis of rheumatoid ar...
Heuristic Approach Uncovering Biological Significance of Gene-Lifestyle Interactions in Cardiometabolic Traits [0.03%]
用于发现基因生活方式相互作用的生物学意义的启发式方法心血管代谢性状中的基因-生活方式交互作用的启发式分析方法
Rodrigo San-Cristobal,Juan de Toro-Martín,Marie-Claude Vohl
Rodrigo San-Cristobal
Background: Gene-lifestyle interaction studies using genome-wide association studies (GWAS) data contribute to a better understanding of individual responses to environmental exposures. ...
Effects of Acute Caffeine Intake on Insulin-Like Growth Factor-1 Responses to Total Sleep Deprivation: Interactions with COMT Polymorphism - A Randomized, Crossover Study [0.03%]
急性咖啡因摄入对总睡眠剥夺后胰岛素样生长因子-1反应的影响：与COMT多态性的相互作用——一项随机交叉研究
Catherine Drogou,Fabien Sauvet,Mégane Erblang et al.
Catherine Drogou et al.
Introduction: Genes encoding catechol-O-methyl-transferase (COMT) and adenosine A2A receptor (ADORA2A) have been shown to influence cognitive performances and responses to caffeine intake during prolonged wakefulness. The...
Randomized Controlled Trial
Lifestyle genomics. 2023;16(1):113-123. DOI:10.1159/000529897 2023
Vitamin D Metabolism Genes Are Differentially Methylated in Individuals with Chronic Knee Pain [0.03%]
维生素D代谢基因在慢性膝关节疼痛患者中的甲基化状态不同
Larissa J Strath,Lingsong Meng,Asha Rani et al.
Larissa J Strath et al.
Introduction: Recent evidence suggests that vitamin D may interact with the epigenome and play a role in the pain experience. In order for proper functioning to occur, there must be an adequate level of vitamin D present,...
Discrimination Exposure and Polygenic Risk for Obesity in Adulthood: Testing Gene-Environment Correlations and Interactions [0.03%]
成人肥胖的歧视暴露和多基因风险：测试基因-环境相关性和交互作用
Adolfo G Cuevas,Frank D Mann,Robert F Krueger
Adolfo G Cuevas
Introduction: Exposure to discrimination has emerged as a risk factor for obesity. It remains unclear, however, whether the genotype of the individual can modulate the sensitivity or response to discrimination exposure (g...
Observational Study
Lifestyle genomics. 2023;16(1):90-97. DOI:10.1159/000529527 2023
Abdominal Obesity, Excessive Adiposity, and the Taq1B CETP Variant Are Positively Associated with Serum Lipid Levels in Mexican Women [0.03%]
腹部肥胖，过度脂肪过多和Taq1B CETP变异基因与墨西哥女性血清脂质水平呈正相关关系
Mariana Perez-Robles,Wendy Campos-Perez,Joel Torres-Vanegas et al.
Mariana Perez-Robles et al.
Introduction: Obesity is a prevalent multifactorial disease whose main complication is dyslipidemia. Serum lipid levels also depend on genetic factors including the Taq1B variant of the CETP gene, which is suggested to be...
Genome Tectonics: Linking Dynamic Genome Organization with Cellular Nutrients [0.03%]
基因组地台学：动态基因组组织与细胞营养的关联
Morgan Fleming,Fina Nelson,Iain Wallace et al.
Morgan Fleming et al.
Background: Our daily intake of food provides nutrients for the maintenance of health, growth, and development. The field of nutrigenomics aims to link dietary intake/nutrients to changes in epigenetic status and gene exp...
Nutrigenomics: Perceptions of South African Dietitians and General Practitioners [0.03%]
营养基因组学：南非营养师和全科医生的看法
Desiré Greyvensteyn,Corinna May Walsh,Mariette Nel et al.
Desiré Greyvensteyn et al.
Introduction: Although investigations into the emerging field of nutrigenomics are relatively limited and more research in this field is required, experts agree that there is potential for it to be incorporated into healt...
Mechanism of Glycitein in the Treatment of Colon Cancer Based on Network Pharmacology and Molecular Docking [0.03%]
基于网络药理学和分子对接的大豆异黄酮甘察汀治疗结肠癌的机制研究
Tao Xiang,Weibiao Jin
Tao Xiang
Introduction: The prevalence of colon cancer remains high across the world. The early diagnosis of colon cancer is challenging. Moreover, patients with colon cancer frequently suffer from poor prognoses. ...