Klotho, Kidneys and Micronutrient Signaling, a Promising Paradigm for Healthy Aging [0.03%]
克洛斯蛋白、肾脏与微量元素信号转导：健康老龄化的前景范式
Sara Mahdavi
Sara Mahdavi
Klotho, a transmembrane protein with pleiotropic anti-aging properties, is increasingly recognized as a central regulator of longevity and metabolic resilience. Primarily expressed in the kidneys and brain, Klotho governs phosphate and calc...
Redefining Malignant Hyperthermia: Multi-omics Insights into a Complex Anesthetic Disorder [0.03%]
重新定义恶性高热：复杂麻醉障碍的多组学见解
Cassandra Thachuk,Darragh Barry,Jackie Trink
Cassandra Thachuk
Malignant hyperthermia (MH) is a rare but serious pharmacogenetic disorder triggered by specific anesthetic agents, leading to a rapid and often fatal hypermetabolic response. While its genetic roots-primarily involving RYR1 and CACNA1S mut...
Machine learning-based prediction of gout using polygenic risk scores and clinical variables: A Korean cohort study [0.03%]
基于机器学习的痛风预测研究：利用多基因风险评分和临床变量的韩国队列研究
Do-Hyeon Kwak,Hyunjung Kim,Hee-Won Park et al.
Do-Hyeon Kwak et al.
The prevalence of gout, a chronic metabolic disease, has recently increased. Polygenic risk scores (PRS) represent a useful tool for predicting patient outcomes of this condition. However, the clinical utility of PRS in disease prediction r...
UPV Austral Summer Course and RINN22 Meeting: Precision nutrition and nutriomics [0.03%]
阿根廷巴里洛切国际精准营养和营养组学暑期培训班通知（现场+线上）
Begoña de Cuevillas,J Alfredo Martinez
Begoña de Cuevillas
Awareness of genetic testing and its impact on changing behavior among general population of U.S - Health Information National Trends Survey (HINTS 2022) [0.03%]
美国普通人群对基因检测的认识及其对行为变化的影响——来自健康信息国家趋势调查（HINTS 2022）的数据分析
Athar Memon,Hiba Hamid,Ayesha Mehboob et al.
Athar Memon et al.
Introduction: This study aims to determine the frequency of genetic testing awareness, the number of individuals who have undergone genetic testing, and the subsequent behavior changes following testing. ...
Linking dietary creatine to DNA methylation-based predictors of mortality in individuals aged 50 and above [0.03%]
将饮食中的肌酸与DNA甲基化相关的预测死亡率的指标联系起来（50岁以上人群）
Sergej M Ostojic,Ivana Kavecan
Sergej M Ostojic
Background: Creatine is a conditionally essential nutrient integral to cellular energy homeostasis, with emerging evidence suggesting its potential role in modulating biological aging. However, associations between dietar...
Experimental environment is a determinant of gene methylation and one-carbon metabolism in obese adult mice [0.03%]
实验环境决定肥胖成年小鼠的基因甲基化和一碳代谢状况
Zeyu Yang,Ruslan Kubant,Eva Kranenburg et al.
Zeyu Yang et al.
Background: Diet-induced obesity (DIO) leads to insulin resistance (IR) and alters gene expression through epigenetic mechanisms, including DNA methylation. Here, we aimed to investigate whether experimental environment i...
New Insight into Mechanisms Underlying Genotype-Dependent Responses to the Mediterranean Diet: Implications for the Future of Precision Nutrition [0.03%]
地中海饮食的基因型依赖性响应机制的新见解：对精准营养未来的启示
Patrick V McTavish,Mathieu J Clavet
Patrick V McTavish
N/A. The Author(s). Published by S. Karger AG, Basel.
Omar Ramos-Lopez,Begoña de Cuevillas,Maria P Portillo et al.
Omar Ramos-Lopez et al.
Editorial
Lifestyle genomics. 2025 Jun 5:1-10. DOI:10.1159/000546650 2025