Experimental environment is a determinant of gene methylation and one-carbon metabolism in obese adult mice [0.03%]
实验环境决定肥胖成年小鼠的基因甲基化和一碳代谢状况
Zeyu Yang,Ruslan Kubant,Eva Kranenburg et al.
Zeyu Yang et al.
Background: Diet-induced obesity (DIO) leads to insulin resistance (IR) and alters gene expression through epigenetic mechanisms, including DNA methylation. Here, we aimed to investigate whether experimental environment i...
New Insight into Mechanisms Underlying Genotype-Dependent Responses to the Mediterranean Diet: Implications for the Future of Precision Nutrition [0.03%]
地中海饮食的基因型依赖性响应机制的新见解：对精准营养未来的启示
Patrick V McTavish,Mathieu J Clavet
Patrick V McTavish
N/A. The Author(s). Published by S. Karger AG, Basel.
Omar Ramos-Lopez,Begoña de Cuevillas,Maria P Portillo et al.
Omar Ramos-Lopez et al.
Editorial
Lifestyle genomics. 2025 Jun 5:1-10. DOI:10.1159/000546650 2025
Type 2 diabetes polygenic risk score interactions with lifestyle risk factors in Black Americans [0.03%]
美国黑人中与生活方式风险因素相互作用的2型糖尿病多基因风险评分
Ashley W Scadden,Aastha Kakar,Elizabeth M Litkowski et al.
Ashley W Scadden et al.
Introduction Prior work in predominantly European ancestry populations has explained how the risk associated with demographic, lifestyle, and health factors differs with underlying genetic susceptibility to type 2 diabetes (T2D), but less i...
A Pilot Study to Evaluate the Role of Obesity and Genetic Variants in Serum C-Reactive Protein Response to an Acute Fructose Load [0.03%]
肥胖和基因变异在急性果糖负荷下血清C反应蛋白反应中的作用的初步研究
Sai Sravani Vennam,Valentina Talevi,Geethika Venkataraman et al.
Sai Sravani Vennam et al.
33 Introduction: Excess fructose intake has been linked to increased risk for dyslipidemia, insulin, 34 resistance, hyperuricemia, inflammation, and obesity. In this human study, we investigated if serum 35 CRP concentrations change after f...
Mariëtte Abrahams
Mariëtte Abrahams
Editorial
Lifestyle genomics. 2025 Feb 13:1-7. DOI:10.1159/000543483 2025
CC genotype at TCF7L2 diabetes risk locus rs7903146 directs a coordinated fatty acid response to a Mediterranean diet intervention: a randomized controlled trial [0.03%]
TCF7L2糖尿病风险基因座rs7903146的CC基因型指导了地中海饮食干预的协同脂肪酸反应：一项随机对照试验
Laurence D Parnell,Chao-Qiang Lai,Christina Holzapfel et al.
Laurence D Parnell et al.
Introduction: Previous studies identified genetic links between the TCF7L2 C/T variant rs7903146, type 2 diabetes (T2D), and obesity. We wished to deepen our understanding of how specific diets interact with this variant ...
Proteomics and recurrence of atrial fibrillation: a pilot study nested in the PREDIMAR trial [0.03%]
蛋白质组学与房颤复发：PREDIMAR试验中的一项前瞻性队列研究
Cristina Razquin,Joaquín Fernandez-Irigoyen,María Teresa Barrio-López et al.
Cristina Razquin et al.
Introduction: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia worldwide. Although catheter ablation is the most efficacious therapy, relapses occur frequently (30%) in the first year after ablatio...
UCP variants are linked to hypercholesterolemia and abdominal obesity in metabolically unhealthy women [0.03%]
UCP基因变异与代谢不健康女性的高胆固醇和中心性肥胖有关
Erika Sierra-Ruelas,Nathaly Torres-Castillo,Barbara Vizmanos et al.
Erika Sierra-Ruelas et al.
Introduction: It has been reported that even with the same body mass index (BMI), there are subjects with metabolically healthy or unhealthy phenotype. The main determinants of the unhealthy phenotype are the type and dis...
Nicotine Metabolism-Related Genetic Polymorphisms Associated with Smoking Cessation in Korean Men: A Candidate Gene Association Study in a Korean Cohort [0.03%]
韩国男性吸烟者尼古丁代谢相关基因多态性与戒烟关系的候选基因关联研究
Jae-Min Park,Ja-Eun Choi,Ji-Won Lee et al.
Jae-Min Park et al.
Introduction: Smoking cessation is influenced by genetic and environmental factors, particularly genetic polymorphisms influencing nicotine metabolism. This study investigated the association between specific nicotine met...