Constructing the constitutively active ribosomal protein S6 kinase 2 from Arabidopsis thaliana (AtRPS6K2) and testing its activity in vitro [0.03%]
来自拟南芥的组成型活性核糖体蛋白S6激酶2（AtRPS6K2）的构建及其体外活性检测
A V Zhigailov,G E Stanbekova,D K Beisenov et al.
A V Zhigailov et al.
Ribosomal protein S6 (RPS6) is the only phosphorylatable protein of the eukaryotic 40S ribosomal subunit. Ribosomes with phosphorylated RPS6 can selectively translate 5'TOP-(5'-terminal oligopyrimidine)-containing mRNAs that encode most pro...
Modern classification and molecular-genetic aspects of osteogenesis imperfecta [0.03%]
现代骨生成不全的分类及分子遗传学方面的问题
A R Zaripova,R I Khusainova
A R Zaripova
Osteogenesis imperfecta (imperfect osteogenesis in the Russian literature) is the most common hereditary form of bone fragility, it is a genetically and clinically heterogeneous disease with a wide range of clinical severity, often leading ...
R N Mustafin,E K Khusnutdinova
R N Mustafin
The article is about the role of transposons in the regulation of functioning of neuronal stem cells and mature neurons of the human brain. Starting from the first division of the zygote, embryonic development is governed by regular activat...
Pharmacological effects of fibroblast growth factor 21 are sex-specific in mice with the lethal yellow (Ay) mutation [0.03%]
纤维芽细胞生长因子21的药理作用在具有致死黄色(Ay)突变小鼠中的性别差异性研究
E N Makarova,T V Yakovleva,N Yu Balyibina et al.
E N Makarova et al.
Hypothalamic melanocortin 4 receptors (MC4R) regulate energy balance. Mutations in the MC4R gene are the most common cause of monogenic obesity in humans. Fibroblast growth factor 21 (FGF21) is a promising antiobesity agent, but its effects...
[Co-expression of glutamatergic and autism-related genes in the hippocampus of male mice with disturbances of social behavior] [0.03%]
雄性小鼠海马区谷氨酸能基因和自闭症相关基因的共表达及其对社会行为的影响
И Л Коваленко,А Г Галямина,Д А Смагин et al.
И Л Коваленко et al.
There is a hypothesis of the involvement of the glutamatergic system in the development of autism. It has been shown that the chronic experience in daily intermale confrontations leads to disturbances in social behavior: a decrease in commu...
[Whole-genome association studies of distribution of developmental abnormalities and other breeding-valuable qualitative traits in offspring of the Russian large-white boars] [0.03%]
俄罗斯大白种公猪后代重要育种性状全基因组关联分析研究
А А Траспов,О В Костюнина,А А Белоус et al.
А А Траспов et al.
Identifying genome regions that are directly or indirectly associated with developmental defects and malformations in domesticated pigs can help identify genomic traits used as biomarkers of the structural and functional composition of the ...
The current state of the problem of in vitro gene pool preservation in poultry [0.03%]
家禽体外基因库保存现状及问题思考
Y L Silyukova,O I Stanishevskaya,N V Dementieva
Y L Silyukova
This review presents the current progress in and approaches to in vitro conservation of reproductive cells of animals, including birds, such as cryopreservation and freeze-drying, as well as epigenetic conditions for restoring viable sperma...
[Fecal microbiome change in patients with ulcerative colitis after fecal microbiota transplantation] [0.03%]
溃疡性结肠炎患者粪菌移植后的肠道微生态变化特征分析
А Ю Тикунов,В В Морозов,А Н Швалов et al.
А Ю Тикунов et al.
Intestinal human microbiota is a dynamic system that is under the pressures of its host organism and external factors. Microbiota disruption caused by these factors can lead to severe diseases including inflammatory and oncological diseases...
Perspectives of using Illumina MiSeq for identification of arbuscular mycorrhizal fungi [0.03%]
illumina miseq在丛枝菌根真菌鉴定中的应用展望
A A Kryukov,A O Gorbunova,E M Machs et al.
A A Kryukov et al.
Arbuscular mycorrhiza fungi (AMF) form one of the most common symbiosis with the majority of land plants. AMF supply the plant with various mineral elements, primarily phosphorus, and improve the water supply. The search for the most effect...
Diversity and occurrence of methylotrophic yeasts used in genetic engineering [0.03%]
甲基营养型酵母的多样性和发生及其在基因工程上的应用
A S Rozanov,E G Pershina,N V Bogacheva et al.
A S Rozanov et al.
Methylotrophic yeasts have been used as the platform for expression of heterologous proteins since the 1980's. They are highly productive and allow producing eukaryotic proteins with an acceptable glycosylation level. The first Pichia pasto...