Rational bioinformatic approach to the analysis of functional properties of metabolites of probiotic microorganisms based on gene network reconstruction [0.03%]
V A Ivanisenko,T M Khlebodarova,M A Kleshchev et al.
V A Ivanisenko et al.
An important direction in industrial microbiology is the development of probiotic strains with valuable consumer properties. The probiotic industry is currently one of the most rapidly developing segments of the food and pharmaceutical sect...
S R Mursalimov,O Yu Shoeva
S R Mursalimov
In different cell layers, cereal grains may accumulate various economically important polyphenols such as colored anthocyanins and melanins and colorless proanthocyanidins. To effectively create new cultivars with different combinations of ...
Different patterns of P transposon and blood retrotransposon distribution in Harwich and Canton-S sub-strains do not affect the manifestation of Drosophila melanogaster intraspecific PM hybrid dysgenesis [0.03%]
L P Zakharenko,Y Y Ilinsky
L P Zakharenko
Intraspecific infertility, the nature of which is not always understood, occurs in many eukaryotes. Intraspecific PM hybrid dysgenesis (PM HD) in Drosophila melanogaster manifests in one cross direction as offspring infertility and other ge...
Modification of the BphP1-QPAS1 optogenetic system for gene expression regulation in Nicotiana benthamiana tobacco leaves using near-infrared light [0.03%]
E S Surkova,Y A Galimova,N V Battulina et al.
E S Surkova et al.
In plants, the regulation of transgene transcription is typically achieved using chemical agents. A safe alternative to chemically induced systems may be optogenetic systems. The BphP1-QPAS1 system has distinct advantages over other optogen...
Soybean locus qDTF-7 as an example of genetic heterogeneity associated with flowering and maturity time [0.03%]
R N Perfil&#x;ev,M I Shmatova,A B Shcherban et al.
R N Perfil&#x;ev et al.
Genome-wide association studies (GWAS) have become a standard approach for identifying quantitative trait loci associated with diverse phenotypic traits. Further investigation of the locus - specifically, the search for the causal gene and ...
A A Gusarova,E A Trifonova,A A Babovskaya et al.
A A Gusarova et al.
Transcriptomics of severe COVID-19. Транскриптомика тяжелой формы COVID-19. ...
Base editing in the AUTS2 gene and high-throughput NGS genotyping of clones: a strategy for generating a cellular model [0.03%]
A P Yan,P A Salnikov,А А Buzdin et al.
A P Yan et al.
Studying the molecular mechanisms underlying autism spectrum disorders (ASD) requires cellular models capable of capturing cis-regulatory effects and allele-specific gene expression. In this study, we present an approach for generating indu...
Single nucleotide polymorphisms are typical for tick-borne encephalitis and West Nile viruses during triple natural mixed infections in Blyth's reed warbler (Acrocephalus dumetorum) [0.03%]
E P Ponomareva,V A Ternovoi,E V Protopopova et al.
E P Ponomareva et al.
Wild bird species contribute significantly to the rapid geographic dissemination of tick-borne encephalitis viruses (TBEV) and West Nile virus (WNV), facilitating the establishment of new natural foci of these orthoflaviviruses. However, th...
Improvement of a phylogenetic footprinting method for transcription factor binding sites recognition based on the use of bootstrap trials for the analysis of large bacterial genomic data [0.03%]
A M Mukhin,T M Khlebodarova,D Yu Oshchepkov
A M Mukhin
The rapid development of high-throughput sequencing technologies has led to an explosive accumulation of high-quality bacterial genome sequence data - their number is approaching three million, and this growth continues. This, in turn, prov...
Genes representing the stress-dependent component in arterial hypertension development [0.03%]
代表应激依赖性成分的基因在动脉高血压发病中的作用
D Yu Oshchepkov,Yu V Makovka,I V Chadaeva et al.
D Yu Oshchepkov et al.
Hypertension is among the major risk factors of many cardiovascular diseases. Chronic psychoemotional stress is one of its key causes. Studies of molecular mechanisms of human hypertension development are conducted in animals, including art...