Apoptosis in the liver of male db/db mice during the development of obesity and type 2 diabetes [0.03%]
肥胖和2型糖尿病小鼠肝脏中的肝细胞凋亡现象研究
S V Michurina,I Yu Ishchenko,S A Arkhipov et al.
S V Michurina et al.
Obesity and diabetes mellitus are known to lead to the development of metabolic syndrome and non-alcoholic fatty liver disease (NAFLD). The mechanisms of programmed cell death are actively involved in maintaining cellular homeostasis along ...
Effect of gonadectomy and estradiol on the expression of insulin signaling cascade genes in female and male mice [0.03%]
输卵管切除和雌二醇对雌雄小鼠胰岛素信号通路基因表达的影响
T V Iakovleva,N E Kostina,E N Makarova et al.
T V Iakovleva et al.
A positive effect of estradiol on insulin sensitivity has been shown for females and males. Insulin sensitivity is higher in females than in males, and males show a greater tendency to develop metabolic disorders. It is believed that these ...
Diagnosis of the mechanisms of different types of discordances between phylogenies inferred from nuclear and mitochondrial markers [0.03%]
核基因和线粒体标记推断的系统发育树不一致机制的诊断
A A Poroshina,D Y Sherbakov,T E Peretolchina
A A Poroshina
In ancient freshwater lakes, an abnormally large species diversity is observed. The mechanisms that generated extremely high biodiversity in the ancient lakes have not been sufficiently studied and remain only partially known. Sequences of ...
Causes of global extinctions in the history of life: facts and hypotheses [0.03%]
历史上生命全球性灭绝的原因:事实与假说
T M Khlebodarova,V A Likhoshvai
T M Khlebodarova
Paleontologists define global extinctions on Earth as a loss of about three-quarters of plant and animal species over a relatively short period of time. At least five global extinctions are documented in the Phanerozoic fossil record (~500-...
Single nucleotide polymorphism and expression of genes for immune competent cell proliferation and differentiation in radiation-exposed individuals [0.03%]
辐射暴露人群免疫细胞增殖和分化相关基因的SNP及表达研究
E A Blinova,V S Nikiforov,M A Yanishevskaya et al.
E A Blinova et al.
It is known that ionizing radiation influences the expression of the genes that play a key role in the mechanisms of maintaining the stability of cellular homeostasis. As a rule, changes in the transcriptome of an exposed cell occur within ...
The role of polymorphic variants of arginase genes (ARG1, ARG2) involved in beta-2-agonist metabolism in the development and course of asthma [0.03%]
ARGIN1和ARG2基因多态性变异在β-2受体激动剂代谢中的作用及对哮喘发生发展的影响研究
O N Savelieva,A S Karunas,Yu Yu Fedorova et al.
O N Savelieva et al.
Asthma is a common severe disease of the respiratory tract, it leads to a significant impairment in the quality of a patient's life unless effectively treated. Uncontrolled asthma symptoms are a cause of disease progression and development,...
Genomics and proteomics of the liver fluke Opisthorchis felineus [0.03%]
猫肝吸虫(Opisthorchis felineus)的基因组学和蛋白质组学研究
V A Mordvinov,N I Ershov,O G Zaparina et al.
V A Mordvinov et al.
The causative agent of opisthorchiasis, the liver fluke Opisthorchis felineus (Rivolta, 1884) is one of the helminths of humans and animals in Russia. Together with closely related species of trematodes O. viverrini (Poirier, 1886) and Clon...
Yu E Uvarova,A V Bryanskaya,A S Rozanov et al.
Yu E Uvarova et al.
For accurate species-level identification of microorganisms, researchers today increasingly use a combination of standard microbiological cultivation and visual observation methods with molecular biological and genetic techniques that help ...
[Resistance to causal agents of late blight and golden potato nematode of the modern cultivars of seed potatoes and their phytosanitary status in various agroclimatic zones of the European part of Russia] [0.03%]
俄罗斯欧洲部分不同农牧气候区马铃薯种用品种的晚疫病和金色马铃薯茎线虫抗性及其植保状态
A V Khiutti,D A Rybakov,T A Gavrilenko et al.
A V Khiutti et al.
The active expansion of foreign potato cultivars on the territory of the Russian Federation has led to a change in the dominant pathogen species and to the emergence of new pathotypes of causal agents of harmful potato diseases. The aim of ...
[Lodging in wheat: genetic and environmental factors and ways of overcoming] [0.03%]
小麦赤霉病的发生规律、致病机理及防控措施研究
E V Ageeva,I N Leonova,I E Likhenko
E V Ageeva
Lodging is one of the main factors in reducing the yield and grain quality of winter and spring wheat varieties. The resistance of wheat cultivars to lodging largely depends on environmental factors, biological and morphological features of...