A S Rozanov,S V Shekhovtsov,N V Bogacheva et al.
A S Rozanov et al.
In this review, we discuss the progress in the study and modification of subtilisin proteases. Despite longstanding applications of microbial proteases and a large number of research papers, the search for new protease genes, the constructi...
A transgenic cell line with inducible transcription for studying (CGG)n repeat expansion mechanisms [0.03%]
一种用于研究(CGG)n重复扩增机制的可诱导转录的转基因细胞系
I V Grishchenko,A A Tulupov,Y M Rymareva et al.
I V Grishchenko et al.
There are more than 30 inherited human disorders connected with repeat expansion (myotonic dystrophy type I, Huntington's disease, Fragile X syndrome). Fragile X syndrome is the most common reason for inherited intellectual disability in th...
Macrostomum lignano as a model to study the genetics and genomics of parasitic flatworms [0.03%]
Macrostomum lignano作为研究寄生扁虫的遗传和基因组学模型
K V Ustyantsev,V Yu Vavilova,A G Blinov et al.
K V Ustyantsev et al.
Hundreds of millions of people worldwide are infected by various species of parasitic flatworms. Without treatment, acute and chronical infections frequently lead to the development of severe pathologies and even death. Emerging data on a d...
Computational analysis of spliced leader trans-splicing in the regenerative flatworm Macrostomum lignano reveals its prevalence in conserved and stem cell related genes [0.03%]
计算分析再生扁虫Macrostomum lignano的拼接领导序列反式剪接现象发现其在保守和干细胞相关的基因中普遍存在
K V Ustyantsev,E V Berezikov
K V Ustyantsev
In eukaryotes, trans-splicing is a process of nuclear pre-mRNA maturation where two different RNA molecules are joined together by the spliceosomal machinery utilizing mechanisms similar to cis-splicing. In diverse taxa of lower eukaryotes,...
The molecular view of mechanical stress of brain cells, local translation, and neurodegenerative diseases [0.03%]
脑细胞机械应力的分子视图、局部翻译和神经退行性疾病
T M Khlebodarova
T M Khlebodarova
The assumption that chronic mechanical stress in brain cells stemming from intracranial hypertension, arterial hypertension, or mechanical injury is a risk factor for neurodegenerative diseases was put forward in the 1990s and has since bee...
Automatic morphology phenotyping of tetra- and hexaploid wheat spike using computer vision methods [0.03%]
基于计算机视觉技术的四倍体和六倍体小麦穗表型自动鉴定方法
A Yu Pronozin,A A Paulish,E A Zavarzin et al.
A Yu Pronozin et al.
Intraspecific classification of cultivated plants is necessary for the conservation of biological diversity, study of their origin and their phylogeny. The modern cultivated wheat species originated from three wild diploid ancestors as a re...
Determination of the quantitative content of chlorophylls in leaves by reflection spectra using the random forest algorithm [0.03%]
基于随机森林算法的叶片反射光谱定量检测叶绿素含量研究
E A Urbanovich,D A Afonnikov,S V Nikolaev
E A Urbanovich
Determining the quantitative content of chlorophylls in plant leaves by their reflection spectra is an important task both in monitoring the state of natural and industrial phytocenoses, and in laboratory studies of normal and pathological ...
Crop pangenomes [0.03%]
作物泛基因组
A Yu Pronozin,M K Bragina,E A Salina
A Yu Pronozin
Progress in genome sequencing, assembly and analysis allows for a deeper study of agricultural plants' chromosome structures, gene identification and annotation. The published genomes of agricultural plants proved to be a valuable tool for ...
The auxin signaling pathway to its PIN transporters: insights based on a meta-analysis of auxin-induced transcriptomes [0.03%]
基于生长素诱导的转录组学的元分析对生长素信号传导通路至其PIN转运蛋白的见解
V V Kovrizhnykh,Z S Mustafin,Z Z Bagautdinova
V V Kovrizhnykh
Active polar transport of the plant hormone auxin carried out by its PIN transporters is a key link in the formation and maintenance of auxin distribution, which, in turn, determines plant morphogenesis. The plasticity of auxin distribution...
Improving the quality of barley transcriptome de novo assembling by using a hybrid approach for lines with varying spike and stem coloration [0.03%]
利用杂交法改善不同花穗和茎秆颜色大麦基因组从头测序质量
N А Shmakov
N А Shmakov
De novo transcriptome assembly is an important stage of RNA-seq data computational analysis. It allows the researchers to obtain the sequences of transcripts presented in the biological sample of interest. The availability of accurate and c...