mRNA technology as one of the promising platforms for the SARS-CoV-2 vaccine development [0.03%]
基于mRNA技术的新型冠状病毒疫苗研发平台
A A Ilyichev,L A Orlova,S V Sharabrin et al.
A A Ilyichev et al.
After the genome sequence of SARS-CoV-2 (Severe acute respiratory syndrome-related coronavirus 2) was published and the number of infected people began to increase rapidly, many global companies began to develop a vaccine. Almost all known ...
[Ecological and genetic assessment of the consequences of radiation influence on contaminated areas] [0.03%]
[辐射污染区生态和遗传影响的评估]
A B Bigaliev,K Z Shalabaeva,B E Shimshikov et al.
A B Bigaliev et al.
The objects of study are the territory of the districts of the West Kazakhstan region of the Republic of Kazakhstan adjacent to the Kapustin Yar test site: Bokeyordinsky, Zhangalinsky, Zhanibeksky, Kaztalovsky, Akzhayiksky and Syrymsky. The...
[Candidate SNP-markers altering TBP binding affinity for promoters of the Y-linked genes CDY2A, SHOX, and ZFY are lowering many indexes of reproductive potential in men] [0.03%]
候选SNP标记物改变了Y染色体基因CDY2A、SHOX和ZFY启动子的TBP结合亲和力，从而降低了男性的多种生殖潜能指标
M P Ponomarenko,E B Sharypova,I A Drachkova et al.
M P Ponomarenko et al.
Reproductive potential is the most important conditional indicator reflecting the ability of individuals in a population to reproduce, survive and develop under optimal environmental conditions. As for humans, the concept of reproductive po...
The cell cycle regulatory gene polymorphisms TP53 (rs1042522) and MDM2 (rs2279744) in lung cancer: a meta-analysis [0.03%]
肺癌中调控细胞周期的基因多态性TP53（rs1042522）和MDM2（rs2279744）：一项系统评价和meta-分析
O Bulgakova,A Kussainova,R Bersimbaev
O Bulgakova
Lung cancer is one of the most common types of cancer in the world. Although the mechanism of lung cancer is still unknown, a large number of studies have found a link between gene polymorphisms and the risk of lung cancer. The tumor suppre...
The composition of peripheral immunocompetent cell subpopulations and cytokine content in the brain structures of mutant Disc1-Q31L mice [0.03%]
Disc1-Q31L突变小鼠外周免疫细胞亚群组成及脑内细胞因子含量变化
M M Gevorgyan,S Ya Zhanaeva,E L Alperina et al.
M M Gevorgyan et al.
The DISC1 (disrupted in sсhizophrenia 1) gene is associated with brain dysfunctions, which are involved in a variety of mental disorders, such as schizophrenia, depression and bipolar disorder. This is the first study to examine the immune...
Pyrenophora tritici-repentis population structure in the Republic of Kazakhstan and identification of wheat germplasm resistant to tan spot [0.03%]
小麦叶枯病菌在哈萨克斯坦的群体结构及抗叶枯病资源鉴定
A M Kokhmetova,N M Kovalenko,M T Kumarbaeva
A M Kokhmetova
Pyrenophora tritici-repentis is a causative agent of tan spot in wheat. In recent years, there has been an increasing spread and harmfulness of wheat tan spot. The aim of the research was to study the racial composition of the P. tritici-re...
[Metabolic phenotype of adult mice offspring obtained from different variants of embryo transfer] [0.03%]
不同供体受体囊胚移植小鼠后代的代谢表型差异研究
M V Anisimova,Ya Gong,N S Yudin et al.
M V Anisimova et al.
Assisted reproductive technologies (ART) increasingly occupy the study of human reproduction. In addition, in developed countries they contribute to breeding of more than 50 % of cattle. In the management of collections of genetic lines of ...
А М Borodin,Ya I Alekseev,K E Gerasimov et al.
А М Borodin et al.
The quantitative trait loci associated with the immune properties of chickens are of interest from the point of view of obtaining animals resistant to infectious agents using marker-assisted selection. In the process of selecting markers fo...
The pattern of genetic diversity of different breeds of pigs based on microsatellite analysis [0.03%]
基于微卫星多态性分析的不同猪品种的遗传多样性格局
V R Kharzinova,N A Zinovieva
V R Kharzinova
One of the main tasks of genetics and animal breeding is the assessment of genetic diversity and the study of genetic relationships between different breeds and populations using molecular genetic analysis methods. We analysed the polymorph...
Phenotypic diversity of bread wheat lines with introgressions from the diploid cereal Aegilops speltoides for technological properties of grain and f lour [0.03%]
来自二倍体野生小黑麦Aegilops speltoides不同片段的面包小麦品系在籽粒和面粉品质上的表型差异性研究
L V Shchukina,I F Lapochkina,T A Pshenichnikova
L V Shchukina
The creation of varieties adapted to changing environmental conditions, resistant to various pathogens, and satisfying various grain purposes is impossible without using the genetic diversity of wheat. One of the ways to expand the genetic ...